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Basic
Network
Structure
Seq./Align.
Variant
Phylogenetic Tree
Pathway
Disease

Detail Data SLC7A2


Basic description
Gene Name SLC7A2
Protein Name Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)
Family SLC7
Category Transport of inorganic cations/anions and amino acids/oligopeptides
Reaction name SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids
SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids
Reaction 1 L-Arg, L-Lys, L-Orn [extracellular region] --> 1 L-Arg, L-Lys, L-Orn [cytosol]
1 L-Arg, L-Lys, L-Orn [extracellular region] --> 1 L-Arg, L-Lys, L-Orn [cytosol]

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 5 8 0 5 9 0 6 0 0 6 1 0 6 2 0 6 3 0 6 4 0 6 5 0 6 6 0 6 7 0 6 8 0 6 9 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550        560        570        580        590        600        610        620        630        640        650        660        670        680        690 
MKIETSGYNS DKLICRGFIG TPAPPVCDSK FLLSPSSDVR MIPCRAALTF ARCLIRRKIV TLDSLEDTKL CRCLSTMDLI ALGVGSTLGA GVYVLAGEVA KADSGPSIVV SFLIAALASV MAGLCYAEFG ARVPKTGSAY LYTYVTVGEL WAFITGWNLI LSYVIGTSSV ARAWSGTFDE LLSKQIGQFL RTYFRMNYTG LAEYPDFFAV CLILLLAGLL SFGVKESAWV NKVFTAVNIL VLLFVMVAGF VKGNVANWKI SEEFLKNISA SAREPPSENG TSIYGAGGFM PYGFTGTLAG AATCFYAFVG FDCIATTGEE VRNPQKAIPI GIVTSLLVCF MAYFGVSAAL TLMMPYYLLD EKSPLPVAFE YVGWGPAKYV VAAGSLCALS TSLLGSMFPL PRILFAMARD GLLFRFLARV SKRQSPVAAT LTAGVISALM AFLFDLKALV DMMSIGTLMA YSLVAACVLI LRYQPGLSYD QPKCSPEKDG LGSSPRVTSK SESQVTMLQR QGFSMRTLFC PSLLPTQQSA SLVSFLVGFL AFLVLGLSVL TTYGVHAITR LEAWSLALLA LFLVLFVAIV LTIWRQPQNQ QKVAFMVPFL PFLPAFSILV NIYLMVQLSA DTWVRFSIWM AIGFLIYFSY GIRHSLEGHL RDENNEEDAY PDNVHAAAEE KSAIQANDHH PRNLSSPFIF HEKTSEF 
CCCCCCCCCC CCCEECCCCC CCCCCCCCHH HCCCCCCCCC CCCHHHHHHH HHHHHHCCCC CCCCCCCCCC CCCCCHHHHH HHHHHHHHCC CHHHHHHHHH HHHCCHHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCHHHHH HHHHHCCCCC CCCCCCHHHH HHHHHHHHHH HHCHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCHHHCCC CHHHHCCCCC CCCCCCCCCC CCCCCCCCCC CCCHHHHHHH HHHHHHHHHH HHHHCCCHHH HHCCCCCHHH HHHHHHHHHH HHHHHHHHHH HCCCCHHHCC CCCHHHHHHH HCCCCHHHHH HHHHHHHHHH HHHHHHCCCH HHHHHHHHHC CCHHHHHHCC CCCCCHHHHH HHHHHHHHHH HHHCCHHHHH HHCCHHHHHH HHHHHHHHHH HCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCHHHH CCCCCHHCCC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC CCCCEEECCC CCCHHHHHHH HHHHHHCCCH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH CCCCCCCCCC CCCCCCCHHH CCCCCCCCCC CCCCCCCCCC CCCCCCC
[Overview] SLC7A1 SLC7A10 SLC7A11 SLC7A13 SLC7A14 SLC7A2 SLC7A3 SLC7A4 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 
SLC7A1    -----------------------------------------MGCKVL-LNIGQQMLRRKVVD-CSRE--------ETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAREN---AGPAIVISFLIAALASVLAGLCYGEFGARVPK-TGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTHM-TLNAPGVLAE-NPD---------IFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSG---FVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKP-GVGGFMPFGFSG--------VLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQ-PEQPNL---------------------------------------------VYQMASTSDELDPADQNELASTN------------------DSQLGFLPEAEMFSLKTILSP-------------KNMEPSKISGLIVNISTSLIAVLIITFCIVTVLGREALTKGALWAVFLLAGSALLCAVVT----------GVIWRQPESKTKLSFKVPFLPVLPILSIFVNVYLMMQLDQGTWVRFAVW-------------MLIGFIIYFGYGLWHSEE------------------------------------------------------------------------ASLDADQA-------RTPDG-------------------NLDQCK---------
SLC7A10   ----MAGH--------------------TQ------------------QPSGRGNPR-PAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHS-GSVGLALFV-WVLGGGVTALGSLCYAELGVAIPK-SGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVI---SMTFSNYVLQPV--------------------FPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRP------------------------------SNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALH-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------IKVNL--LIPVAYLVFWAFLLV---------FSFISEPM-VCGVGVIIILTGVPIFFLGVFW--RSKPKCVHRLTESMTHWGQELCFVVYP--------QDAP----------------------------------EEEENGPCP---PSLLPATDK-----------------PSKPQ------------
SLC7A11   M---VRKP-------------VVSTISKGG------------------YLQGNVNGRLPSLGNKEPPGQ-----EKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNT-GSVGMSLTI-WTVCGVLSLFGALSYAELGTTIKK-SGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVI---SLAFGRYILEPF--------------------FIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKGQTQNFK--------------------------------DAFSG-RDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLRYKCPDMH-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------FKVPL--FIPALFSFTCLFMVA---------LSLYSDPF-STGIGFVITLTGVPAYYLFIIW--DKKPRWFRIMSEKITRTLQIILEVV----------------------------------------------------------------PEEDKL---------------------------------
SLC7A13   MD------------------------------------------------RG----------------------EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCV-WAGCAILAMTSTLCSAEISISFPC-SGAQYYFLKRYFGSTVAFLNLWTSLFL----GSGVVAGQALLLAEYSIQPF--------------------FPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKENVER-----------------------------FQNAFDA-ELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFTGSLWSILLMIGILRRRYQEPNLS-----------------------------------------------------------------------------------------------------------IP-------------------------------------------------------------------------------------------------YKVFL--SFPLATIVIDVGLVV---------IPLVKSPNVHYVYVLLLVLSGLLFYIPLIHF--KIRLAWF----EKMTCYLQLLFNICLPDVS-----EE-------------------------------------------------------------------------------------------
SLC7A14   ----MSGFFT-------------------------SLDPRRVQWGAAWYAMHSRILRTKPVE-SMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEM---AGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPD---------LLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGL-FFING--KYW--------------------------AEGQFLPHGWSG--------VLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ-PESD-IDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYL-----IKLKKLIGPHYYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVV----------LMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVW-------------CFVGLLIYFGYGIWNSTLEISAREEALHQSTYQ----RYDVDDPFSV----EEGFSYATEGESQEDWGGPTEDKGFYYQQMSDAKANGRTSSKAKSKS-------KHKQN-------SEALIAND----ELDYSPE--------
SLC7A2    MKIETSGYNSDKLICRGFIGTPAPPVCDSKFLLSPSSDVRMIPCRAA-LTFARCLIRRKIVTLDSLE--------DTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKAD---SGPSIVVSFLIAALASVMAGLCYAEFGARVPK-TGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLRTYF-RMNYTG-LAE-YPD---------FFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAG---FVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTG--------TLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKR-QSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQ-PGLS------------------------------------------------YDQPKCSPEKDGLGSSPRVTSK-----------------SESQVTML-QRQGFSMRTLFCP--------------SLLPTQQSASLVSFLVGFLAFLVLGLSVLTTYGVHAITRLEAWSLALLA----------LFLVLFVAIVLTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIW-------------MAIGFLIYFSYGIRHSLEGH---------------------------------------------------------------------LRDENNEED-------AYPDNVHAAAEEKSAIQANDHHPRNLSSPFIFHEKTSEF
SLC7A3    -----------------------------------------MPWQAF-RRFGQKLVRRRTLE-SGMA--------ETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDK---AGPSIVICFLVAALSSVLAGLCYAEFGARVPR-SGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSI-ALHVPHVLAE-YPD---------FFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISG---FVKGDVHNWKLTEEDYELAMAEL---NDTYSLGPLGSGGFVPFGFEG--------ILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ-PDQE---------------------------------------------------TKTGEEVEL--QEEAITT---------------------------ESEKLTLWGLFFP-------------LNSIPTPLSGQIVYVCSSLLAVLLTALCLVL----------AQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVW-------------MLIGFAIYFGYGIQHSLEEI---------------------------------------------------------------------KSNQPSRKS-------RAKTV-------------------DLDPGTLYVHSV---
SLC7A4    -------------------------------------MARGLPTIASLARLCQKLNRLKPLEDSTME---------TSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEV---AGPAVLLSFGVAAVASLLAALCYAEFGARVPR-TGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPL-LGH-YPD---------FLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILG---FILAQPHNWSA------------------------DEGGFAPFGFSG--------VMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQ-KSSP------------------------------PSSPGPASPGPLT-----KQQSSFSDHLQLVGTVHASVPE---PG--------------------------ELKPALRPY------------LGFLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTL-HLPHWGYILLL---LLTSVMFLLSLLVLGA-----HQQQYREDL-FQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIW-------------LLMGLAVYFGYGIRHSKENQ--RELPGLNSTH------YVVFPRGSL----EETV----------------------------------QAMQPPSQA-------PAQDP------------------GHME------------
SLC7A5    MA--GAGPKRRAL--------AAPAAEEKE------------------EAREKMLAA-KSADGSAPAGEGEG----VTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEA-GSPGLALVV-WAACGVFSIVGALCYAELGTTISK-SGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIV---ALVFATYLLKPL--------------------FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDP------------------------------NFSFEG-TKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHRKPELE-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------IKVNL--ALPVFFILACLFLIA---------VSFWKTPV-ECGIGFTIILSGLPVYFFGVWW--KNKPKWLLQGIFSTTVLCQKLMQVV-P--------QET------------------------------------------------------------------------------------------
SLC7A6    ME--AREPGRPTPTY-----HLVPNT-----------------------SQSQVEE-----DVSSPPQRSSET---MQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHT-ASYGMSLIV-WAIGGLFSVVGALCYAELGTTITK-SGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAII---AITFANYIIQPS--------------------FPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQ--------------------------------DAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRP-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------LKLSV--FFPIVFCICSVFLVI---------VPLFTDTI-NSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELDV----AEEK----------------------------------KDERKTD------------------------------------------------
SLC7A7    ---------------------MVDSTEYEV------------------ASQPEVETS-PLGDGASP---GPEQ---VKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYS-ASFGLSLVI-WAVGGLFSVFGALCYAELGTTIKK-SGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAII---AITFANYMVQPL--------------------FPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFE--------------------------------NSFEG-SSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRP-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------LKLSV--FFPIVFCLCTIFLVA---------VPLYSDTI-NSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDL----EDGG----------------------------------EMPKQRD---------PKSN-----------------------------------
SLC7A8    ME-EGARHRNNT---------------EKK------------------HPGG------GESDASPEAGSGGGG---VALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENA-GSVGLALIV-WIVTGFITVVGALCYAELGVTIPK-SGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVI---ALTFSNYVLQPL--------------------FPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEP------------------------------KNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIP-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------IKINL--LFPIIYLLFWAFLLV---------FSLWSEPV-VCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEAN----------------------------------EDMEEQQQPMYQPT--PTKDKDV---------------AGQPQP-----------
SLC7A9    --------------------------------------------------MGDTGLRKRREDEKSIQSQEPKT---TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNT-EAVGPCLII-WAACGVLATLGALCFAELGTMITK-SGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAII---CLSFSEYVCAPF--------------------YVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFD--------------------------------NSFEG-AQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELE-----------------------------------------------------------------------------------------------------------RP-------------------------------------------------------------------------------------------------IKVPV--VIPVLMTLISVFLVL---------APIISKPTWEYLYCVLFILSGLLFYFLFVHY----KFGWAQKISKPITMHLQMLMEVVPPE-------ED----------------------------------------------------PE-------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC7A2 16 R/Q 0.140531 rs13259948
-- SLC7A2 28 D/H 0.191238 rs13259978
-- SLC7A2 28 D/N 0.0256823 rs13259978
-- SLC7A2 29 S/R 0.000581484 rs200077616
-- SLC7A2 38 D/H 0.000110771 rs765997833
-- SLC7A2 47 A/T 0.000451159 rs149187759
-- SLC7A2 56 R/W 0.00011158 rs139113545
-- SLC7A2 60 V/M 0.000884117 rs12680645
-- SLC7A2 84 V/I 0.000437612 rs143701037
-- SLC7A2 145 V/L 0.00374725 rs145975234
-- SLC7A2 269 S/P 0.000618848 rs142593316
-- SLC7A2 277 S/C 0.000642499 rs188973136
-- SLC7A2 292 Y/H 0.00346134 rs144865355
-- SLC7A2 295 T/M 0.000163146 rs138338525
-- SLC7A2 416 C/S 0.0252696 rs1134975
-- SLC7A2 480 D/E 0.000131273 rs142262222
-- SLC7A2 495 P/A 0.00010344 rs752981306
-- SLC7A2 533 V/M 0.000195362 rs369646330
-- SLC7A2 544 V/M 0.0181645 rs56335308
-- SLC7A2 554 G/R 0.000242734 rs371137426
-- SLC7A2 570 A/T 0.0879234 rs62622371
-- SLC7A2 574 V/I 0.000521501 rs140110447
-- SLC7A2 614 L/M 0.000179109 rs770530994
-- SLC7A2 622 T/S 0.00221276 rs140440674
-- SLC7A2 664 V/I 0.00015935 rs190140119
-- SLC7A2 681 P/S 0.000334832 rs151179886

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
main SLC7A2 SLC7A2-1 [plasma membrane] Amino acid transport across the plasma membrane
main SLC7A2 SLC7A2-2 [plasma membrane] Amino acid transport across the plasma membrane

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data