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Structure
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Variant
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Disease

Detail Data SLC49A4


Basic description
Gene Name SLC49A4
Protein Name Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2)
Family SLC49
Category -
Reaction name -
Reaction -

Network
No data
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470 
MGSRWSSEEE RQPLLGPGLG PGLGASWRSR EAAAAALPAA VPGPGRVYGR RWLVLLLFSL LAFVQGLVWN TWGPIQNSAR QAYGFSSWDI ALLVLWGPIG FLPCFAFMWL LDKRGLRITV LLTSFLMVLG TGLRCIPISD LILKRRLIHG GQMLNGLAGP TVMNAAPFLS TTWFSADERA TATAIASMLS YLGGACAFLV GPLVVPAPNG TSPLLAAESS RAHIKDRIEA VLYAEFGVVC LIFSATLAYF PPRPPLPPSV AAASQRLSYR RSVCRLLSNF RFLMIALAYA IPLGVFAGWS GVLDLILTPA HVSQVDAGWI GFWSIVGGCV VGIAMARFAD FIRGMLKLIL LLLFSGATLS STWFTLTCLN SITHLPLTTV TLYASCILLG VFLNSSVPIF FELFVETVYP VPEGITCGVV TFLSNMFMGV LLFFLTFYHT ELSWFNWCLP GSCLLSLLLI LCFRESYDRL YLDVVVSV 
CCCCCCCHHC CCCCCCCCCC CCCCCCHHHH HHHHHCCCCC CCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHCHHHHHHH HHHCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHHCHHHHH HHHHHHHHHH HCCCCCCCCC CCCCCHHHHH HCHHHHHHCC CCCCCHHHHH HHCCCHHHHH HHHHHHHHHH HHHCHHHHHH CCCCCCCCCC CCCCHHCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCCCCCCH HHHHHHHHHH HHHHHHHHCH HHHHHHHHHH HCHHHHHHHH CHHHHHCCHH CCCHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCCCHHHH HHHHHHHHHH HHHHCHHHHH HHHHHHHHCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHCC CCCHHHHHHH HHHHHHHHHH HHCCCCCCHH HHHHCCCC
[Overview] SLC49A1 SLC49A2 SLC49A3 SLC49A4 
SLC49A1   --MARPDDEEGAAVAPGHPLAKGYLPLPRGAPVGKESVELQNGPKAGTFPVNGAPRDSLAAASGVLGGPQTPLAPEEETQARLLPAGAGAETPGAESSP--LPLTALSPRRFVVLLIFSLYSLVNAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWIKCGS--VQQHLFWVTML--GQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPNTQNDTNLLACN---------ISTMFYGTSAVATLLFILTAIAFKEKPRYPPSQAQA---ALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFT--------FTL----DLRYIIIVFVTGGV----LGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIF-GIL-------FTLAQGK---LTSDYGPKAGNIFLCVWMFIGII------LTALIKSDLRRHNINIGITNVDVKAI----------------------------------------------------------PADSPTDQEPKTVMLSKQSESAI----------------
SLC49A2   MVNEGPNQEESDDT-----------PVPESA--------LQADPSVSVHP-------SVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHP-SSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYMLTYIPLLLPVAWLLEKFGLRTIALTGSALNCLGAWVKLGS--LKPHLFPVTVV--GQLICSVAQVFILGMPSRIASVWFGANEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIE-DRDELAYH---------ISIMFYIIGGVATLLLILVIIVFKEKPKYPPSRAQSLSYALT-SP--DASYLGSIARLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVIWHYPGEEVNAGRIGLTIVIAGMLGAVISGIWLDRSKTYKETTLVVYIMTLVGMVVYT--------FTL----NLGHLWVVFITAGT----MGFFMTGYLPLGFEFAVELTYPESEGISSGLLNISAQVF-GII-------FTISQGQ---IIDNYGTKPGNIFLCVFLTLGAA------LTAFIKADLRRQKANKETLENKLQEE----------------------------------------------------------EEESNTSKVPTAV-----SEDHL----------------
SLC49A3   --MAGPTEAE-----------------------------------------------------------------------------TGLAEPRALCAQRGH---RTYARRWVFLLAISLLNCSNATLWLSFAPVADVIAEDLVLSMEQINWLSLVYLVVSTPFGVAAIWILDSVGLRAATILGAWLNFAGSVLRMVPCMVVGTQNPFAFLMGGQSLCALAQSLVIFSPAKLAALWFPEHQRATANMLATMSNPLGVLVANVLSPVLVKKGE-DIPL-------------MLGVYTIPAGVVCLL--STICLWESVPPTPPSAGAA-------SS-TSEKFLDGLKLLMWNKAYVILAVCLGGMIGISASFSALLEQILCASGHSSGF-SGLCGALFITFGILGALALGPYVDRTKHFTEATK-------IGLCLFS---LACVPFAL-----VSQLQGQTLALAATCSLLGLFGFSVGPVAMELAVECSFPVGEGAATGMIFVLGQAE-GILIMLAMTALTVRRSEPSLSTCQQGEDPLDWTVSLLLMAGLCTFFSCILAVFFHTPYRRLQAESGEPPSTRNAVGGADSGPGVDRGGAGRAGVLGPSTATPECTARGASLEDPRGPGSPHPACHRATPRAQGPAATDAPSRPGRLAGRVQASRFIDPAGSHSSFSSPWVIT
SLC49A4   MGSRWSSEEERQ-------------PL------------L--GPGLG--PGLGASWRSREA--------------------------AAAALPAAVPGPG-----RVYGRRWLVLLLFSLLAFVQGLVWNTWGPIQNSARQAYGFSSWDIALLVLWGPIGFLP-CFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIP--ISDLILKRRLIHGGQMLNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLVGPLVVPAPNGTSPLLAAESSRAHIKDRIEAVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAA-------SQ--RLSYRRSVCRLLSNFRFLMIALAYAIPLGVFAGWSGVLD-LILTPAHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRG---------MLKLILLLLFSGATLSSTWFTLTCLNSITHLPLTTVTLYASCILLGVFLNSSVPIFFELFVETVYPVPEGITCGVVTFLSNMFMGVLLF----FLTFYHTE---LSWFNWCLPGSCLLSLLLILCF-----------------RESYDRLYLDVVVSV--------------------------------------------------------------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC49A4 222 A/V 0.000175045 rs371361425
-- SLC49A4 226 D/Y 0.00114983 rs139292426
-- SLC49A4 228 I/V 0.000230791 rs147611410
-- SLC49A4 281 R/Q 0.000363188 rs147781467
-- SLC49A4 355 S/L 0.00021945 rs763882530
-- SLC49A4 397 V/M 0.000135333 rs375393527

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data