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Detail Data SLC46A2


Basic description
Gene Name SLC46A2
Protein Name Thymic stromal cotransporter homolog (Solute carrier family 46 member 2)
Family SLC46
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470 
MSPEVTCPRR GHLPRFHPRT WVEPVVASSQ VAASLYDAGL LLVVKASYGT GGSSNHSASP SPRGALEDQQ QRAISNFYII YNLVVGLSPL LSAYGLGWLS DRYHRKISIC MSLLGFLLSR LGLLLKVLLD WPVEVLYGAA ALNGLFGGFS AFWSGVMALG SLGSSEGRRS VRLILIDLML GLAGFCGSMA SGHLFKQMAG HSGQGLILTA CSVSCASFAL LYSLLVLKVP ESVAKPSQEL PAVDTVSGTV GTYRTLDPDQ LDQQYAVGHP PSPGKAKPHK TTIALLFVGA IIYDLAVVGT VDVIPLFVLR EPLGWNQVQV GYGMAAGYTI FITSFLGVLV FSRCFRDTTM IMIGMVSFGS GALLLAFVKE TYMFYIARAV MLFALIPVTT IRSAMSKLIK GSSYGKVFVI LQLSLALTGV VTSTLYNKIY QLTMDMFVGS CFALSSFLSF LAIIPISIVA YKQVPLSPYG DIIEK 
CCCCCCCCCC CCCCCCCCCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHCC CCCCCCCCCC CCCCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCHHHHHH HHHHHHHHHH HHHHHHHHCC CCHHHHHHHH HHHHHCHHHH HHHHHHHHHH HHCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCHHHHHHH HHHHHHHHHH HHHHHHHHCC CCCCCCCCCC CCCCCCCCCC CCCCCCCHHH CCCHHHCCCC CCCCCCCCHH HHHHHHHHHH HHHHHHHCCC CCEEEEEHHC CCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHCCHHHHH HHHHHHHHHH HHHHHHHHCC HHHHHHHHHH HHHHHCHHHH HHHHHHHHCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHCCCCCCCC CCCCC
[Overview] SLC46A1 SLC46A2 SLC46A3 
SLC46A1   MEGSASPPEK---PRARPAAAVLCRGPVEPLVFLANFALVLQGPLTTQYLWHRFSADLG----YNGTRQRGGCSNRSADPTM-----QEVETLTSHWTLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQA----LVSVFVVQLQLHVGYFVLGRILCALLGDFGGLLAASFASVAD-VSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-GYANPFWLALALLI---AMTL-YAAFCFG--ETLKEPKSTRL-------FTFRHHRSI--------VQLYVAPAPEKSRKHLALYSLAIFVVITVHF---GAQDILTLYELSTPLCWDSKLIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYGLLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTASGIFNSLYPATLNFMKGFPFLLGAGLLLIPAVLIGMLE-----KADPHLEFQQFPQSP-------
SLC46A2   MSPEVTCPRRGHLPRFHP------RTWVEPVVASSQVAASLY--------------DAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALN----GLFGGFSAFWSGVMALGSL-GSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKP-SQELPAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVA------------YKQVPLSPYGDIIEK
SLC46A3   -------------------MKILF---VEPAIFLSAFAMTLTGPLTTQYVYRRIWEETGN-YTFSSDSNISECEKNKSSPIF--AFQEEVQKKVSRFNLQMDISGLIPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIG----AFCGNYTTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTGLSSGYFIREL-GFEWSF-LIIAVSL---AVNLIYILFFLG--DPVKECSSQNVTMSCSEGFKNLFYRTY--------MLFKNA-----SGKRRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALGSASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVPFSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAGLLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDR---

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC46A2 9 R/Q 0.000678718 rs145291738
-- SLC46A2 12 H/P 0.00102757 rs3802490
-- SLC46A2 95 G/R 0.000119393 rs553409959
-- SLC46A2 167 G/S 0.0117326 rs61742087
-- SLC46A2 197 Q/H 0.000155887 rs111991367
-- SLC46A2 236 P/R 0.00937142 rs76734829
-- SLC46A2 257 D/N 0.00559572 rs112054166
-- SLC46A2 327 G/A 0.00108343 rs146384415
-- SLC46A2 353 I/T 0.000692003 rs148086697
-- SLC46A2 366 A/V 0.00121971 rs16917454
-- SLC46A2 388 V/I 0.000116452 rs563108402
-- SLC46A2 459 V/M 0.00335325 rs74339125

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data