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Structure
Seq./Align.
Variant
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Pathway
Disease

Detail Data SLC45A3


Basic description
Gene Name SLC45A3
Protein Name Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein)
Family SLC45
Category Cellular hexose transport
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550 
MVQRLWVSRL LRHRKAQLLL VNLLTFGLEV CLAAGITYVP PLLLEVGVEE KFMTMVLGIG PVLGLVCVPL LGSASDHWRG RYGRRRPFIW ALSLGILLSL FLIPRAGWLA GLLCPDPRPL ELALLILGVG LLDFCGQVCF TPLEALLSDL FRDPDHCRQA YSVYAFMISL GGCLGYLLPA IDWDTSALAP YLGTQEECLF GLLTLIFLTC VAATLLVAEE AALGPTEPAE GLSAPSLSPH CCPCRARLAF RNLGALLPRL HQLCCRMPRT LRRLFVAELC SWMALMTFTL FYTDFVGEGL YQGVPRAEPG TEARRHYDEG VRMGSLGLFL QCAISLVFSL VMDRLVQRFG TRAVYLASVA AFPVAAGATC LSHSVAVVTA SAALTGFTFS ALQILPYTLA SLYHREKQVF LPKYRGDTGG ASSEDSLMTS FLPGPKPGAP FPNGHVGAGG SGLLPPPPAL CGASACDVSV RVVVGEPTEA RVVPGRGICL DLAILDSAFL LSQVAPSLFM GSIVQLSQSV TAYMVSAAGL GLVAIYFATQ VVFDKSDLAK YSA 
CCCCCCHHHC CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCH HHHHHHHHHC CCCEEECCCC CCCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH CCCHHHHCCH HHHHHHHHHH HHHHHHHHHH HCCCCCCCCC CCCHHHHHHH HHHHHHHHHH HHHHHHHEEC CCCCCCCCCC CCCCCCCCCC CCCCHHCCHH CCCHHHHHHH HHHCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCCCC CCHHHHHHHC CHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCHHHHHHHH HHHHHHHHHH CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC CCCCCCCCCC CHHHHHHHHC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCEE EEEECCCCCC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHCCCH HHHHHHHHHH HHHHHHHHHH CCCCHHHHHH HCC
[Overview] SLC45A1 SLC45A2 SLC45A3 SLC45A4 
SLC45A1   MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVL-----LQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIAL-ADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQ-DRGLNIHALLAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLP--LPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSV----P--------RPPISVSFPRAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDTSK---PRSSGILKRP----QTL--------AIPDAAGGGGPETS-------------------RRRNVTFSQQV---------------------ANILLNGVKYESEL-----------------------TGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEK-LEEF-LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYY-----QSKKFAGSSADGTR--------------------------------------------------------------RGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVIYEIPP--SDAADEEH------------------RPLLLNV-------------------------------------------------------------------------------------------------
SLC45A2   ---------------------------MGSNSGQAGRHI-------------YKSLADDGPFDSVEP------------PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVL-----LSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFIDGPIKAYLFDVCSHQDK-EKGLHYHALFTGFGGALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPL-----TEVAKGIP-------------PQQTPQD-------------------------------------------------------------------------------------PPLS------SDGMY-----------------------EYGSIEKVK---------------------------------NGYVNPE-------------------------------------------------------LAMQGAKNKNH---------------------------AEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGFCINSVFSSLYSYFQKV-LVSY-IGLKGLYFTGYLLFGLGTGFIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSV--------------------------------------------------------------RGKGMDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRY---------VD-----------------------------------------------------------------------------------------------------------------------------
SLC45A3   MV------------------QRLW----------VSRLLRHRK-----------------------------------------AQLLLVNLLTFGLEVCLAAGITYVPPLL-----LEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASDHWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPDPR---PLELALLILGVGLLDFCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLGTQEECLFGLLTLIFLTCVAATLLVAEEAAL-GPTE---------------------PAEGLSA-------------------------------------------------------------------------------------PSLS----------------------------------------------PH-----------------------CCP------------------------------CRARLAF---------------------------------RNLGAL-----------------------------------LPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDR-LVQR-FGTRAVYLASVAAFPVAAGATCLSHSVAVVTASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEPTEARVVPGRGICLDLAILDSAFLLSQVAPSLFMGSIVQLSQSVTAYMVSAAGLGLVAIYFATQVVFDK-----SDLAKYSA--------------------------------------------------------------------------------------------------------------------------
SLC45A4   ---------------------------MGKASPASGLSR----------------------------------------PK------------------------TLVSPLRSNQWSLQKGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGVALFLNGSAIGLAL-GDVPNRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQ-DMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIIFTVSVALHLFSIDEEQY-SPQQERSAEEPGALDGGEPHGVPAFPDEVQSE-------------------------------------HELA-------LDYPDVDIMRSKSDSALHVPDTALDLEPELLFLHDIEPSIF------HDASY------------PATP-------RSTSQELAKTKLPRLATFLKEAAKEDETLLDNHLNEAKVP--NGSGSPTKDALGGYTRVDTKPSATSSSMRRRRHAFRRQASSTFSYYGKLGSHCYRYRRANAVVLIKPSRSMSDLYDMQKRQRQHRHRNQSGATTSSGDTESEEGEGETTVRLLWLSMLKMPRELMRLCLCHLLTWFSVIAEAVFYTDFMGQVIFEGDPKAPSNSTAWQAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSVRVIYVLGTLGFSVGTAVMAMFPNVYVAMVTISTMGIVSMSISYCPYALLGQYH-----DIKQYIHHSPGNSK--------------------------------------------------------------RGFGIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFLVIY---PNVSEEAKEEQKGLSSPLAGEGRAGGNSEKPTVLKLTRKEGLQGPVETERLQVLTSVRSRHIGWCRSCWRVFFFMIILEKKFSFPQCGSLRRMTYLLFLSELDTLCPGQPCPWAATAHQSWEEAGPGGLGRRQ

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC45A3 34 A/T 0.000210751 rs149769508
-- SLC45A3 86 R/W 0.000371635 rs116503331
-- SLC45A3 113 L/V 0.00029003 rs141243660
-- SLC45A3 251 R/W 0.00324025 rs537311786
-- SLC45A3 255 A/V 0.000179789 rs142713511
-- SLC45A3 259 R/W 0.000106115 rs377389106
-- SLC45A3 266 R/H 0.000182148 rs750557568
-- SLC45A3 296 V/M 0.000279796 rs150262445
-- SLC45A3 318 D/E 0.000125706 rs200416305
-- SLC45A3 361 A/T 0.000135598 rs140300319
-- SLC45A3 377 V/M 0.00170373 rs150525587
-- SLC45A3 390 S/P 0.000103488 rs548833685
-- SLC45A3 415 R/Q 0.000597378 rs145712905
-- SLC45A3 470 V/I 0.00692262 rs137949511
-- SLC45A3 484 P/L 0.000159511 rs200659267
-- SLC45A3 486 R/W 0.00013951 rs142259819
-- SLC45A3 492 L/V 0.00114316 rs148291270
-- SLC45A3 528 A/T 0.00095107 rs151018622

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
main SLC45A3 SLC45A3 [plasma membrane] Cellular hexose transport

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data