Menu |
Basic |
Network |
Structure |
Seq./Align. |
Variant |
Phylogenetic Tree |
Pathway |
Disease |
Detail Data SLC44A5
Basic description
Gene Name | SLC44A5 |
---|---|
Protein Name | Choline transporter-like protein 5 (Solute carrier family 44 member 5) |
Family | SLC44 |
Category | Transport of bile salts and organic acids, metal ions and amine compounds |
Reaction name | - |
Reaction | - |
[Overview]
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 MNDTEKPADT PSEEEDFGDP RTYDPDFKGP VANRSCTDVL CCMIFLLCII GYIVLGLVAW VHGDPRRAAY PTDSQGHFCG QKGTPNENKT ILFYFNLLRC TSPSVLLNLQ CPTTQICVSK CPEKFLTYVE MQLLYTKDKS YWEDYRQFCK TTAKPVKSLT QLLLDDDCPT AIFPSKPFLQ RCFPDFSTKN GTLTIGSKMM FQDGNGGTRS VVELGIAANG INKLLDAKSL GLKVFEDYAR TWYWILIGLT IAMVLSWIFL ILLRFIAGCL FWVFMIGVIG IIGYGIWHCY QQYTNLQERP SSVLTIYDIG IQTNISMYFE LQQTWFTFMI ILCIIEVIVI LMLIFLRNRI RVAIILLKEG SKAIGYVPST LVYPALTFIL LSICICYWVV TAVFLATSGV PVYKVIAPGG HCIHENQTCD PEIFNTTEIA KACPGALCNF AFYGGKSLYH QYIPTFHVYN LFVFLWLINF VIALGQCALA GAFATYYWAM KKPDDIPRYP LFTAFGRAIR YHTGSLAFGS LIIALIQMFK IVLEYLDHRL KRTQNTLSKF LQCCLRCCFW CLENAIKFLN RNAYIMIAIY GRNFCRSAKD AFNLLMRNVL KVAVTDEVTY FVLFLGKLLV AGSIGVLAFL FFTQRLPVIA QGPASLNYYW VPLLTVIFGS YLIAHGFFSV YAMCVETIFI CFCEDLERND GSTEKPYFVT PNLHGILIKK QLVPQKQKE CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HCCCHHHEEC EECCCCCCCC CCCCCCCCCE EEEEECCHHH CCHHHHHCCC CCCCEEECCC CCHHHHHHHH HHHHHHCCCC CHHCCCCCCC CCCCCCCHHH HHHHCCCCCC CCCCCCCCCC CCCCCCCCCC CCEEECEEEE EECCCCCCEE HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC CCCCEEEECC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCHHC CHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCEEEECCCC CCCCCCCCCC CHHCCCCHHH HHCCCCCEEE EEECCCCCCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHCCCCHHHC CCCHHHHHHH HHHHHHHCCC CHHCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC CCCCCCCCCH HHHHHHHHHH HHHHHHCHHH HHHHHHHHHH HHHHCHHHCC CCCCCCCCCC HHHHHHHHHH CCCCHHHCC
[Overview]
SLC44A1 MGC----CSS---ASSAAQSSKREWK---PLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVSGYDSYGNICGQKNTKLEAIPNSGMDHTQRKYVFFLD--PCNLDLI-------NRKIKSVALCVAACPRQELKTLSDVQKFAEINGSA-------LCSYNLKPSEYTTSPKSSVLCPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSV---------LHRLISG------VMTSKE---------------IILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKE------TVTPEQLQIAEDNLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFLGTTGSPVQNEQGFVEFKIS-----GP--------------------------------------------LQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK-RNLPFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKEN-ACARCVLKSCICCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFMLFLGKVLIVCSTGLAGIMLLN----------YQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRK---AMKEAGKGGVADSR--ELKPMASGASSA SLC44A2 MGD-----ERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQK----------GTKNENKPYLFYFNIVKCASPLVLLE-----FQCPTPQICVEKCPDRYLTY-------LNARSSRDFEYYKQFCVPGFKNNKGVAEVLQDGDCPAVLIPSK---PLARRCFPA----IHAYKGVL-MVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLVI-AMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAV--------YKIFD---DSP---CPFTAKTCNPETFPSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAEN-KFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQD--TAPPLNYYWVPILTVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTN------KKAAES-------------------- SLC44A3 MHC----LGAEYLVSAEGAPRQREWR---PQIYRKCTDTAWLFLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNMCGKKNSPVEGAPLSGQDMTLKKHVFFMN--SCNLEVK-------GTQLNRMALCVSNCPEEQLDSLEEVQFFANTSGSF-------LCVYSLNSFNYTHSPKADSLCPRLPVPPSKSFPLFNRCVPQTPECYSLFASVLI---NDVDT---------LHRILSG------IMSGRD---------------TILGLCILALALSLAMMFTFRFITTLLVHIFISLVILGLLFVCGVLWWLYYDYTND-----------LSIELDTERENMKCVLGFAIVSTGITAVLLVLIFVLRKRIKLTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSLGTAGAAQVMEGGQVEYKPL-----SG--------------------------------------------IRYMWSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNRSK-NDPPDHPILSSLSILFFYHQGTVVKGSFLISVVRIPRIIVMYMQNALKEQQHGALSRYLFRCCYCCFWCLDKYLLHLNQNAYTTTAINGTDFCTSAKDAFKILSKNSSHFTSINCFGDFIIFLGKVLVVCFTVFGGLMAFN----------YNRAFQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVDLETNDGSSEKPYFMDQEFLSFVKRSNKLNNARAQQDKHSLRNEEGTELQAIVR----- SLC44A4 MGG----KQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGM------------GENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGK--NEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSA---PALGRCFPW----TNVTPPALPGITNDTTIQQG------ISGLIDS-------LNARDISVKIFEDFAQSWYWILVALGV-ALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGAS---ISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQ--------YVLWASNISSPGCEKVPINTSCNPT---AHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQN-PVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK--------------------- SLC44A5 MNDTEKPADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAWVHGDPRRAAYPTDSQGHFCGQK----------GTPNENKTILFYFNLLRCTSPSVLLN-----LQCPTTQICVSKCPEKFLTYVE--MQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSK---PFLQRCFPD----FSTKNGTL-TIGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYARTWYWILIGLTI-AMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERPSSVLTIYDIGIQTNISMYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGYVPSTLVYPALTFILLSICICYWVVTAVFLATSGVPV--------YKVI-----APGGHCIHENQTCDPEIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALAGAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLKRTQN-TLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVLKVAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQ--GPASLNYYWVPLLTVIFGSYLIAHGFFSVYAMCVETIFICFCEDLERNDGSTEKPYFVTPNLHGILIKKQLVP---QKQKE---------------------
Variant
check | gene name | residue number | Reference Amino Acid / Variant Amino Acid | minor allele frequency | rs number |
---|---|---|---|---|---|
-- | SLC44A5 | 10 | T/S | 0.000374708 | rs200976396 |
-- | SLC44A5 | 23 | Y/H | 0.000338238 | rs202031898 |
-- | SLC44A5 | 105 | V/M | 0.000119508 | rs147564575 |
-- | SLC44A5 | 138 | D/E | 0.00332851 | rs41291498 |
-- | SLC44A5 | 226 | D/Y | 0.00038115 | rs143251034 |
-- | SLC44A5 | 299 | R/C | 0.000131219 | rs149696907 |
-- | SLC44A5 | 344 | I/L | 0.00751076 | rs138027438 |
-- | SLC44A5 | 410 | G/E | 0.000828672 | rs146910557 |
-- | SLC44A5 | 507 | R/Q | 0.00352545 | rs143004355 |
-- | SLC44A5 | 676 | E/Q | 0.000147662 | rs529370554 |
-- | SLC44A5 | 699 | V/I | 0.000199338 | rs78856933 |
Phylogenetic tree
Pathway
Priority | Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|---|
main | SLC44A5 | SLC44A5 [plasma membrane] | Transport of bile salts and organic acids, metal ions and amine compounds |
SLC44A5 | SLC44A5 [plasma membrane] | Synthesis of PC |
Disease
Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|
No data |