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Detail Data SLC41A2


Basic description
Gene Name SLC41A2
Protein Name Solute carrier family 41 member 2
Family SLC41
Category Transport of bile salts and organic acids, metal ions and amine compounds
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550        560        570 
MTNSKGRSIT DKTSGGPSSG GGFVDWTLRL NTIQSDKFLN LLLSMVPVIY QKNQEDRHKK ANGIWQDGLS TAVQTFSNRS EQHMEYHSFS EQSFHANNGH ASSSCSQKYD DYANYNYCDG RETSETTAML QDEDISSDGD EDAIVEVTPK LPKESSGIMA LQILVPFLLA GFGTVSAGMV LDIVQHWEVF RKVTEVFILV PALLGLKGNL EMTLASRLST AVNIGKMDSP IEKWNLIIGN LALKQVQATV VGFLAAVAAI ILGWIPEGKY YLDHSILLCS SSVATAFIAS LLQGIIMVGV IVGSKKTGIN PDNVATPIAA SFGDLITLAI LAWISQGLYS CLETYYYISP LVGVFFLALT PIWIIIAAKH PATRTVLHSG WEPVITAMVI SSIGGLILDT TVSDPNLVGI VVYTPVINGI GGNLVAIQAS RISTYLHLHS IPGELPDEPK GCYYPFRTFF GPGVNNKSAQ VLLLLVIPGH LIFLYTIHLM KSGHTSLTII FIVVYLFGAV LQVFTLLWIA DWMVHHFWRK GKDPDSFSIP YLTALGDLLG TALLALSFHF LWLIGDRDGD VGD 
CCCCCCCCCC CCCCCCCCCC CCCCCCEEEC CCCCCCCHHH HHCCCCCEEC CCCHHHHHHH CCCCCCCCCC CCCCCCCCCC CCCHHCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCHHHHC CCCCCCCCCC CCCCCCCCCC CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCCHHHHHH HHHHCCCCCH HHHHHHHHHH HHHCCCCCCH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH CCHHCCCHHH HHHHHHHHHH HHHHHHHHHC CCCHHCCCCC CCCCHHHHHH HHHHHHHHHH CCCCCCCCCH HCCCCEECCH HHHHHHHHHH HCCHHHHCCC CCCCCCCCCC CCCCCCHHCC CCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC CCC
[Overview] SLC41A1 SLC41A2 SLC41A3 
SLC41A1   MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIES-----RANAKGV-------------------------REEDALLENGSQSN---------------------------ESDDVSTDRG-----PAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLA-------------------------------LSFHVLWLIGDRDTDVGD
SLC41A2   -MTNSKGRSITDKTSGGPSSGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKANGIWQDGLSTAVQTFSNRSEQHMEYHSFSEQSFHANNGHASSSCSQKYDDYANYNYCDGRETSETTAMLQDEDISSDGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDE-PKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFGAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLA-------------------------------LSFHFLWLIGDRDGDVGD
SLC41A3   -MDGTETRQRRLDSCGKPGE-------------------LGLP---------------HPLSTG----GLPVA-----------------SEDGALRAPESQSVTPK---------------------------------------PLETEPSRETAWSIGLQVTVPFMFAGLGLSWAGMLLDYFQHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQEQHRVISSNLALIQVQATVVGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKLGVNPDNIATPIAASLGDLITLSILALVSSFFYRHKDS-RYLTPLVCLSFAALTPVWVLIAKQSPPIVKILKFGWFPIILAMVISSFGGLILSKTVSKQQYKGMAIFTPVICGVGGNLVAIQTSRISTYLHMWSAPGVLPLQMKKFWPNPCSTFCTSEINSMSARVLLLLVVPGHLIFFYIIYLVEGQSVINSQTFVVLYLLAGLIQVTILLYLAEVMVRLTWHQALDPDNHCIPYLTGLGDLLGSSSVGHTAAVPRRCTASPGWGLIQPFICTQHLIVSLLSFYFPFCLLAKTSI---

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC41A2 15 G/V 0.00315179 rs61745056
-- SLC41A2 36 D/N 0.000370288 rs78726424
-- SLC41A2 60 K/R 0.00017049 rs768950324
-- SLC41A2 248 A/T 0.000114009 rs142913469
-- SLC41A2 275 S/C 0.000109042 rs201983610
-- SLC41A2 477 I/V 0.000283233 rs570315588

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
main SLC41A2 SLC41A2 [plasma membrane] Metal ion SLC transporters

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data