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Seq./Align.
Variant
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Pathway
Disease

Detail Data SLC38A7


Basic description
Gene Name SLC38A7
Protein Name Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)
Family SLC38
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460 
MAQVSINNDY SEWDLSTDAG ERARLLQSPC VDTAPKSEWE ASPGGLDRGT TSTLGAIFIV VNACLGAGLL NFPAAFSTAG GVAAGIALQM GMLVFIISGL VILAYCSQAS NERTYQEVVW AVCGKLTGVL CEVAIAVYTF GTCIAFLIII GDQQDKIIAV MAKEPEGASG PWYTDRKFTI SLTAFLFILP LSIPREIGFQ KYASFLSVVG TWYVTAIVII KYIWPDKEMT PGNILTRPAS WMAVFNAMPT ICFGFQCHVS SVPVFNSMQQ PEVKTWGGVV TAAMVIALAV YMGTGICGFL TFGAAVDPDV LLSYPSEDMA VAVARAFIIL SVLTSYPILH FCGRAVVEGL WLRYQGVPVE EDVGRERRRR VLQTLVWFLL TLLLALFIPD IGKVISVIGG LAACFIFVFP GLCLIQAKLS EMEEVKPASW WVLVSYGVLL VTLGAFIFGQ TTANAIFVDL LA 
CCCCCCCCCC CCCCCCCCCC CHHHHCCCCC CCCCCCCCCC CCCCCCCCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCHHHHHH HHHCHHHHHH HHHHHHHHHH CHHHHHHHHH HHCHHHHHHH HCCCCCCCCC CCCCCHHHHH HHHHHHHHHH HCCCCHHCHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC CCCCCCCCCC HHHHHHHHHH HHHHHHCHHC CCCHHHHCCC CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH HCHHCCCCCH HHCCCCCCHH HHHHHHHHHH HHHCCHHHHH HHHHHHHHHH HHHHCCCCCC CCCCCHHHHH HHHHHHHHHH HHHHHHHCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHCC CCCCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HC
[Overview] SLC38A1 SLC38A10 SLC38A11 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC38A6 SLC38A7 SLC38A8 SLC38A9 
SLC38A1   MMHFKS---GLELTELQ--------NMTV-PEDDNISNDSN-DFT-------EVENG-QINSKFIS-----------DRESRRSL----------------------TNSHLEKKK------CDEYIPG------TTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYS-INLLLICSKE-----TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETF-------------------------------------------SAWYVDGRVLVVIVTFGIILPLCLLKN-LGYLGYTSGFSLSCMVFFLIVVIYKKFQIPC-------------------------IVP------ELN------------------------STISANSTN--ADTCTPKYVTFNSKTVY-ALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMF--VMYFLTAIFGYLTF------YDNVQSDLLHKYQS--KDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKKTK-----------------------FNLCRHTVV-TCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKIT--DQDGDKGTQRIWAAL----FLGLGVLFSLVSIPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VIYDWACSSSSDEGH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A10  ------------------------------------------------------MTA-AAAS---------------------------------------------------------------------------NWGL-ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQS-CMFLVKSASL-----SKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG--------------------------------------------GTFRM---FLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGL-----------------------------------------------------------------------FSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVT--TFYVMVGFFGYVSF------TEATAGNVLMHFPS----NLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQK----------DGTFA---AGGYMPPLRFKAL-TLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI---HKNALSSQVVL--------WVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES
SLC38A11  -----------------------------------------------------------------------------------------------------------------------------------------------------------------MKQAGFPLGILLLFWVSYVTDFS-LVLLIKGGAL-----SGTDTYQSLVNKTFGFPGYLLLSVLQFLYPFIAMISYNIIAGDTLSKVFQRIPGVDPE---------------------------------------------NVFIGRHFIIGLSTVTFTLPLSLYRN-IAKLGKVSLISTGLTTLILGIVMARAISLGPHIP-----------------------------------------------------------------------KTEDAWVFAKPNAIQ-AVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISV--FICIFFATCGYLTF------TGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGN------------------------LSSVFHIVV-TVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKL---SEEPRTHSDKIMSCV----MLPIGAVVMVFGFVM---------------------------------------------------------------------------------------------------------------AITNTQD--------------------------------------------------------------------------------------------------CTH-----------------------------------------------------------------GQEMFYC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPDNFSLTNTSESHVQQTT-----------------------------------------------------------------------------------------------------------QLS----------------------TLNISIFQ------------------------
SLC38A2   ----------MKKAEMG--------RFSISPDEDSSSYSSNSDFNYSY----PTKQA-ALKSHYADV----------DPENQNFL----------------------LESNLGKKK-----YETEFHPG------TTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYS-VHLLLKTANE-----GGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKT-------------------------------------------GLWYLNGNYLVLLVSLVVILPLSLFRN-LGYLGYTSGLSLLCMVFFLIVVICKKFQVPC--PVEAALIINETINTTLT--QPTALVP----------------------------------ALSHNVTE--NDSCRPHYFIFNSQTVY-AVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMF--LMYLLAALFGYLTF------YEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKD-----------------------FSWWRHSLI-TVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLV--KKEPMKSVQKIGALF----FLLSGVLVMTGSMAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVLDWVHNAPGGGH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A3   ------------------------------------------------------MEA-PLQTEMVELV-------PNGKHSEGLLPVI-TPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTD--FEG------KTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYS-IHLLLKSSGV-----VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKT-------------------------------------------SDWYMNGNYLVILVSVTIILPLALMRQ-LGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP--------PNFNNTTGNFSHVEIVK-------------------------------EKVQLQVEPEA--SAFCTPSYFTLNSQTAY-TIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMY--IMYFLAALFGYLTF------YNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQE-----------------------FSWLRHVLI-AVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALC----FAMLGFLLMTMSLSF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIIDWASGTSRHGGNH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A4   ----------MDPMELR--------NVNIEPDDESSSGESAPD---SYIGIGNSEKA-AMSSQFANE----------DTESQKFL----------------------TNGFLGKKKLAD--YADEHHPG------TTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYS-VHLLLKTAKE-----GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENT-------------------------------------------GEWYLNGNYLIIFVSVGIILPLSLLKN-LGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLP--MHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHS--DDKCEPKYFVFNSRTAY-AIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGML--VMYLLAALFGYLTF------YGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP-----------------------FSWIRHFLI-AAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLV--KKETFRSPQKVGALI----FLVVGIFFMIGSMAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIIDWIYDPPNSKHH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A5   -------------MELQ-------------------------D---------PKMNG-ALPSDAVGY----------RQEREGFLPSR-GPAPGSKPVQ----------------------FMD--FEG------KTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYS-IHLLLTCAGI-----AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE--------------------------------------------GDWFLKGNLLIIIVSVLIILPLALMKH-LGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAI-------------------GHNETAM-------------------------------ESEALVGLPSQGLNSSCEAQMFTVDSQMSY-TVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMF--CMYGLTATFGYLTF------YSSVKAEMLHMYSQKDP---LILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKA-----------------------FSWPRHVAI-ALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALC----FGVLGVLFMAVSLGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFANWATGQSRMSGH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A6   ------------------------------------------------------MEA-SWGSFNAERGWYVSVQQPEEAEAEELSPL--------------------LSNELHRQR----------SPG-------VSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYS-VHLLLSMCIQ-----TAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYS--------------------------------------------RYWYLDGQTLLIIICVGIVFPLALLPK-IGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPL--------------------------------TLNY-----------------------VEKGFQISN-VTDDCKPKLFHFSKESAY-ALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSF--LIYFISALFGYLTF------YDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFP-----------------------FSWIRHFLI-TLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSS--------------------------------------------------------------------------------------------------NPPTSASRVAETTGRDT----------------------------------------------------ME------------------------------------------MCTQRKG-----------------------------------------------------------HARTQQEGNCLQAKGRG---------------------------------LRRTKRVH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLILHFPTSRTVSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A7   ------------------------------------------------------MAQVSINNDYSEWDL-----STDAGERARLL-------------QSP------CVDTAPKSEWEA-------SPGGLDRGTTSTLGA-IFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQA-----SNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGA------------------------------------------SGPWYTDRKFTISLTAFLFILPLSIPRE-IGFQKYASFLSVVGTWYVTAIVIIK-YIWPDKEMTP----------------GNILTRP------------------------------------------------------ASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIAL--AVYMGTGICGFLTF------GAAVDPDVLLSYPS---EDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRY-------------QGVPVEEDVG--RERRRRVLQ-TLVWFLLTLLLALFIPDIGKVISVIGGLAA-CFIFVFPGLCLIQAKLSEMEEVKPASWW-------VLVSYGVLLVTLGAFI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGQTTANA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFVDLLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A8   ------------------------------------------------------MEG-----------------------------------------QTP------GSRGLPEKPHPA-------TAA----ATLSSMGA-VFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAV-----SGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPA------------------------------------------PQPWYADQRFTLPLLSVLVILPLSAPRE-IAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRE----------------SHPSLSP------------------------------------------------------ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACC--LIYSLTGVYGFLTF------GTEVSADVLMSYPG---NDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWV------------RMPL-TILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIFIFPGLCLICA--MGVEPIGPRVKC-------CLEVWGVVSVLVGTFI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGQSTAAA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VWEMF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A9   MANMNSDSRHLGTSEVDHERDPGPMNIQFEPSDLRSKRPFCIEPT-NIVNVNHVIQRVSDHASAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSP------LGSAYKLQS---------YTEG---YGKNTSLVT-IFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYC-CYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW-DKSRTVPFYLVGLLLPLLNFKS-PSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHLEFHWFI-------------PTEFFVP----------------------------------EIRFQFPQ--------------------LTGVLTLAFFIHNCII----TLLKNNKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPS---SDTLSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDI------------------------YPSIFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISL--HQEERLTWPKLIFHVF---IIILGVANLIVQFFM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC38A7 10 Y/C 0.00567033 rs151075190
-- SLC38A7 46 L/P 0.0320338 rs7193572
-- SLC38A7 61 V/I 0.000184873 rs372554338
-- SLC38A7 78 T/I 0.15774 rs7191331
-- SLC38A7 90 M/T 0.000223739 rs201621133
-- SLC38A7 105 A/V 0.00253167 rs111738115
-- SLC38A7 123 R/H 0.0003003 rs147209769
-- SLC38A7 162 A/V 0.00159016 rs148206922
-- SLC38A7 175 D/E 0.000195 rs143031096
-- SLC38A7 284 M/I 0.000120031 rs140010248
-- SLC38A7 318 Q/R 0.000159125 rs540133010
-- SLC38A7 320 T/M 0.00393441 rs117111840
-- SLC38A7 422 M/I 0.00013521 rs754045767

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data