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Basic
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Structure
Seq./Align.
Variant
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Pathway
Disease

Detail Data SLC38A11


Basic description
Gene Name SLC38A11
Protein Name Putative sodium-coupled neutral amino acid transporter 11 (Solute carrier family 38 member 11)
Family SLC38
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400 
MKQAGFPLGI LLLFWVSYVT DFSLVLLIKG GALSGTDTYQ SLVNKTFGFP GYLLLSVLQF LYPFIAMISY NIIAGDTLSK VFQRIPGVDP ENVFIGRHFI IGLSTVTFTL PLSLYRNIAK LGKVSLISTG LTTLILGIVM ARAISLGPHI PKTEDAWVFA KPNAIQAVGV MSFAFICHHN SFLVYSSLEE PTVAKWSRLI HMSIVISVFI CIFFATCGYL TFTGFTQGDL FENYCRNDDL VTFGRFCYGV TVILTYPMEC FVTREVIANV FFGGNLSSVF HIVVTVMVIT VATLVSLLID CLGIVLELNG VLCATPLIFI IPSACYLKLS EEPRTHSDKI MSCVMLPIGA VVMVFGFVMA ITNTQDCTHG QEMFYCFPDN FSLTNTSESH VQQTTQLSTL NISIFQ 
CHHCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCHH HHHHHHCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHCHHH HHHHCCCCCH HHHHHHHHHH HHHHHHHHHH HHHCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC CCCCCCHHCC CCCHHHHHHH HHHHHHHHHC CCCCCCCCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCHHCC HHCCCCCCCH HHHHHHHHHH HHHHHCHHHH HHHHHHHHHH HHHCCCCCHH HHHHHHHHHH HHHHHHHHCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCC
[Overview] SLC38A1 SLC38A10 SLC38A11 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC38A6 SLC38A7 SLC38A8 SLC38A9 
SLC38A1   MMHFKS---GLELTELQ--------NMTV-PEDDNISNDSN-DFT-------EVENG-QINSKFIS-----------DRESRRSL----------------------TNSHLEKKK------CDEYIPG------TTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYS-INLLLICSKE-----TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETF-------------------------------------------SAWYVDGRVLVVIVTFGIILPLCLLKN-LGYLGYTSGFSLSCMVFFLIVVIYKKFQIPC-------------------------IVP------ELN------------------------STISANSTN--ADTCTPKYVTFNSKTVY-ALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMF--VMYFLTAIFGYLTF------YDNVQSDLLHKYQS--KDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKKTK-----------------------FNLCRHTVV-TCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKIT--DQDGDKGTQRIWAAL----FLGLGVLFSLVSIPL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VIYDWACSSSSDEGH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A10  ------------------------------------------------------MTA-AAAS---------------------------------------------------------------------------NWGL-ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQS-CMFLVKSASL-----SKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG--------------------------------------------GTFRM---FLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGL-----------------------------------------------------------------------FSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVT--TFYVMVGFFGYVSF------TEATAGNVLMHFPS----NLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQK----------DGTFA---AGGYMPPLRFKAL-TLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI---HKNALSSQVVL--------WVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES
SLC38A11  -----------------------------------------------------------------------------------------------------------------------------------------------------------------MKQAGFPLGILLLFWVSYVTDFS-LVLLIKGGAL-----SGTDTYQSLVNKTFGFPGYLLLSVLQFLYPFIAMISYNIIAGDTLSKVFQRIPGVDPE---------------------------------------------NVFIGRHFIIGLSTVTFTLPLSLYRN-IAKLGKVSLISTGLTTLILGIVMARAISLGPHIP-----------------------------------------------------------------------KTEDAWVFAKPNAIQ-AVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISV--FICIFFATCGYLTF------TGFTQGDLFENYCR---NDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGN------------------------LSSVFHIVV-TVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKL---SEEPRTHSDKIMSCV----MLPIGAVVMVFGFVM---------------------------------------------------------------------------------------------------------------AITNTQD--------------------------------------------------------------------------------------------------CTH-----------------------------------------------------------------GQEMFYC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPDNFSLTNTSESHVQQTT-----------------------------------------------------------------------------------------------------------QLS----------------------TLNISIFQ------------------------
SLC38A2   ----------MKKAEMG--------RFSISPDEDSSSYSSNSDFNYSY----PTKQA-ALKSHYADV----------DPENQNFL----------------------LESNLGKKK-----YETEFHPG------TTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYS-VHLLLKTANE-----GGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKT-------------------------------------------GLWYLNGNYLVLLVSLVVILPLSLFRN-LGYLGYTSGLSLLCMVFFLIVVICKKFQVPC--PVEAALIINETINTTLT--QPTALVP----------------------------------ALSHNVTE--NDSCRPHYFIFNSQTVY-AVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMF--LMYLLAALFGYLTF------YEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKD-----------------------FSWWRHSLI-TVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLV--KKEPMKSVQKIGALF----FLLSGVLVMTGSMAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVLDWVHNAPGGGH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A3   ------------------------------------------------------MEA-PLQTEMVELV-------PNGKHSEGLLPVI-TPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTD--FEG------KTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYS-IHLLLKSSGV-----VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKT-------------------------------------------SDWYMNGNYLVILVSVTIILPLALMRQ-LGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP--------PNFNNTTGNFSHVEIVK-------------------------------EKVQLQVEPEA--SAFCTPSYFTLNSQTAY-TIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMY--IMYFLAALFGYLTF------YNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQE-----------------------FSWLRHVLI-AVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALC----FAMLGFLLMTMSLSF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIIDWASGTSRHGGNH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A4   ----------MDPMELR--------NVNIEPDDESSSGESAPD---SYIGIGNSEKA-AMSSQFANE----------DTESQKFL----------------------TNGFLGKKKLAD--YADEHHPG------TTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYS-VHLLLKTAKE-----GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENT-------------------------------------------GEWYLNGNYLIIFVSVGIILPLSLLKN-LGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLP--MHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHS--DDKCEPKYFVFNSRTAY-AIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGML--VMYLLAALFGYLTF------YGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP-----------------------FSWIRHFLI-AAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLV--KKETFRSPQKVGALI----FLVVGIFFMIGSMAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIIDWIYDPPNSKHH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A5   -------------MELQ-------------------------D---------PKMNG-ALPSDAVGY----------RQEREGFLPSR-GPAPGSKPVQ----------------------FMD--FEG------KTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYS-IHLLLTCAGI-----AGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPE--------------------------------------------GDWFLKGNLLIIIVSVLIILPLALMKH-LGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAI-------------------GHNETAM-------------------------------ESEALVGLPSQGLNSSCEAQMFTVDSQMSY-TVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMF--CMYGLTATFGYLTF------YSSVKAEMLHMYSQKDP---LILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKA-----------------------FSWPRHVAI-ALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALC----FGVLGVLFMAVSLGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFANWATGQSRMSGH------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A6   ------------------------------------------------------MEA-SWGSFNAERGWYVSVQQPEEAEAEELSPL--------------------LSNELHRQR----------SPG-------VSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYS-VHLLLSMCIQ-----TAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYS--------------------------------------------RYWYLDGQTLLIIICVGIVFPLALLPK-IGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPL--------------------------------TLNY-----------------------VEKGFQISN-VTDDCKPKLFHFSKESAY-ALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSF--LIYFISALFGYLTF------YDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFP-----------------------FSWIRHFLI-TLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSS--------------------------------------------------------------------------------------------------NPPTSASRVAETTGRDT----------------------------------------------------ME------------------------------------------MCTQRKG-----------------------------------------------------------HARTQQEGNCLQAKGRG---------------------------------LRRTKRVH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLILHFPTSRTVSK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A7   ------------------------------------------------------MAQVSINNDYSEWDL-----STDAGERARLL-------------QSP------CVDTAPKSEWEA-------SPGGLDRGTTSTLGA-IFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQA-----SNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGA------------------------------------------SGPWYTDRKFTISLTAFLFILPLSIPRE-IGFQKYASFLSVVGTWYVTAIVIIK-YIWPDKEMTP----------------GNILTRP------------------------------------------------------ASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIAL--AVYMGTGICGFLTF------GAAVDPDVLLSYPS---EDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRY-------------QGVPVEEDVG--RERRRRVLQ-TLVWFLLTLLLALFIPDIGKVISVIGGLAA-CFIFVFPGLCLIQAKLSEMEEVKPASWW-------VLVSYGVLLVTLGAFI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGQTTANA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFVDLLA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A8   ------------------------------------------------------MEG-----------------------------------------QTP------GSRGLPEKPHPA-------TAA----ATLSSMGA-VFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAV-----SGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPA------------------------------------------PQPWYADQRFTLPLLSVLVILPLSAPRE-IAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRE----------------SHPSLSP------------------------------------------------------ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACC--LIYSLTGVYGFLTF------GTEVSADVLMSYPG---NDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWV------------RMPL-TILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIFIFPGLCLICA--MGVEPIGPRVKC-------CLEVWGVVSVLVGTFI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGQSTAAA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VWEMF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC38A9   MANMNSDSRHLGTSEVDHERDPGPMNIQFEPSDLRSKRPFCIEPT-NIVNVNHVIQRVSDHASAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSP------LGSAYKLQS---------YTEG---YGKNTSLVT-IFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYC-CYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW-DKSRTVPFYLVGLLLPLLNFKS-PSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHLEFHWFI-------------PTEFFVP----------------------------------EIRFQFPQ--------------------LTGVLTLAFFIHNCII----TLLKNNKKQENNVRDLCIAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPS---SDTLSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDI------------------------YPSIFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISL--HQEERLTWPKLIFHVF---IIILGVANLIVQFFM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC38A11 4 A/T 0.000151937 rs147209705
-- SLC38A11 19 R/S 0.000279182 rs188253825
-- SLC38A11 32 T/N 0.000202489 rs756739515
-- SLC38A11 43 N/S 0.000102509 rs773977412
-- SLC38A11 47 F/S 0.00161724 rs139693718
-- SLC38A11 63 P/S 0.000693229 rs140192021
-- SLC38A11 104 S/P 0.000347725 rs138491284
-- SLC38A11 116 R/Q 0.0003267 rs140708593
-- SLC38A11 133 T/A 0.00268292 rs77858556
-- SLC38A11 167 A/V 0.000107493 rs764538386
-- SLC38A11 254 L/W 0.000129277 rs142297772
-- SLC38A11 295 V/L 0.00242652 rs141629634

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data