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Detail Data SLC31A1


Basic description
Gene Name SLC31A1
Protein Name High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1)
Family SLC31
Category Transport of bile salts and organic acids, metal ions and amine compounds
Reaction name SLC31A1 transports Cu2+ from extracellular region to cytosol
Reaction 1 Cu2+ [extracellular region] --> 1 Cu2+ [cytosol]

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190 
MDHSHHMGMS YMDSNSTMQP SHHHPTTSAS HSHGGGDSSM MMMPMTFYFG FKNVELLFSG LVINTAGEMA GAFVAVFLLA MFYEGLKIAR ESLLRKSQVS IRYNSMPVPG PNGTILMETH KTVGQQMLSF PHLLQTVLHI IQVVISYFLM LIFMTYNGYL CIAVAAGAGT GYFLFSWKKA VVVDITEHCH  
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCHHHHCC CEEEEEEECC CCCCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHCCCC CCCCCCCCCC CCCCCHHHHH HHHHHHHHCH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC CCCCCCCCCC
[Overview] SLC31A1 SLC31A2 
SLC31A1   MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFP-----------HLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
SLC31A2   ------MAMHFIFSDTAV-------------------------------------LLFDFWSVHSPAGMALSVLVLLLLAVLYEGIKVGKAKLLNQVLV-----NLPTSISQQTIAETDGDSAGSD--SFPVGRTHHRWYLCHFGQSLIHVIQVVIGYFIMLAVMSYNTWIFLGVVLGSAVGYYL-----AYPLLSTA---

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC31A1 25 P/A 0.00581067 rs2233915
-- SLC31A1 151 P/H 0.275927 rs10124895
-- SLC31A1 180 M/T 0.000168336 rs371732349

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
main SLC31A1 SLC31A1 [plasma membrane] Metal ion SLC transporters

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data