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Basic
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Structure
Seq./Align.
Variant
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Pathway
Disease

Detail Data SLC30A4


Basic description
Gene Name SLC30A4
Protein Name Zinc transporter 4 (ZnT-4) (Solute carrier family 30 member 4)
Family SLC30
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420 
MAGSGAWKRL KSMLRKDDAP LFLNDTSAFD FSDEAGDEGL SRFNKLRVVV ADDGSEAPER PVNGAHPTLQ ADDDSLLDQD LPLTNSQLSL KVDSCDNCSK QREILKQRKV KARLTIAAVL YLLFMIGELV GGYIANSLAI MTDALHMLTD LSAIILTLLA LWLSSKSPTK RFTFGFHRLE VLSAMISVLL VYILMGFLLY EAVQRTIHMN YEINGDIMLI TAAVGVAVNV IMGFLLNQSG HRHSHSHSLP SNSPTRGSGC ERNHGQDSLA VRAAFVHALG DLVQSVGVLI AAYIIRFKPE YKIADPICTY VFSLLVAFTT FRIIWDTVVI ILEGVPSHLN VDYIKEALMK IEDVYSVEDL NIWSLTSGKS TAIVHIQLIP GSSSKWEEVQ SKANHLLLNT FGMYRCTIQL QSYRQEVDRT CANCQSSSP 
CCCCCHHHHH HHHHHCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCEEE CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC CCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCHHHHHH HHHHHHHHHH HHHHHCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC HHHHHHHHHC CCCEEEEEEE EEEEECCCCE EEEEEEEECC CCCHHHHHHH HHHHHHHHHH HCCCEEEEEE EECCCCCCCC CCCCCCCCC
[Overview] SLC30A1 SLC30A10 SLC30A2 SLC30A3 SLC30A4 SLC30A5 SLC30A6 SLC30A7 SLC30A8 SLC30A9 
SLC30A1   -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGC-----------------------------------WGRNRGR--------------LLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDV----------------------------------------LALVVALVAERFAR-RTHATQKNTFGWIRAEVMGALVNAIFLTGL-CFAILLEAIERFIEPH---------EMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGF--------------SQDSGHGHSHG-GHGHGHGLPKGPR--VKSTRPGS-SDINVAPGEQGPDQE-ETNTLVANTSNSNGLKLDPADPENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLNMRGVFL-----HVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFP----DPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQID--IRNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKC---------EDPTSYMEVAKTIKDVFHNH-GIHATTIQPEFASVG-----------------------------SKSSVVPCELACRTQ-CALKQCC--GTLPQAPSGKDAEKTPAVSISCLELSNNLEKKPRRTKAENIPAVVIEIK---------------------------------------NMPNKQPESSL-------
SLC30A10  -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGR-----------------------------------YSGKTCR--------------LLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDL----------------------------------------ISLCVGLSAGYIAR-RPTRGFSATYGYARAEVVGALSNAVFLTAL-CFTIFVEAVLRLARPE---------RIDDPELVLIVGVLGLLVNVVGLLIFQDCAAWFACCLRGRSRRLQQRQQLAEGCVPG-AFGGPQG-AEDPRRAADPTAPGSDSAVTLRGTSVERKRE-KGATVFANV-----------------AGDSFNTQ------NEPEDMMKKEKKSEALNIRGVLL-----HVMGDALGSVVVVITAIIFY---------------VLPLKSEDPCN-------------------WQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVN--MEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKY---------PKDRGYQDASTKIREIFHHA-GIHNVTIQFENVDLKEPL-------------------------EQKDLLLLCNSPCISKGCAKQLCCPPGALPLAHVNGCAEHNGGPSLDTYG-SDGLSRRDAR-------EVAIEVSL--------------DSCLSD----------------HGQSLNKTQEDQCYVNRTHF
SLC30A2   ME---------------------------------------------------------AKEKQHLLDARPAIRS------------------------------------------------------YTGS----L----------------------------------------------------------WQE----------------------------------------------------------------------------------------------G----------------------------------------------------------------------------------------------------------AGWIPLPRPGLD---------LQAIELAAQSNHHCHAQKGPDSHCDP------------------KKGKAQRQ-------------LYVASAICLLFMIGEVVGGYLAHSLAVMTDAAHLLTDF----------------------------------------ASMLISLFSLWMSSRPATKTMN--FGWQRAEILGALVSVLSIWVV-TGVLVYLAVERLISGD--------YEIDGGTMLI-TSGCAVAVNIIMGLTLHQ---------------------SGHGHSHG-TTNQQEE---------------------------------------------------------------------------------------NPSVRAAFI-----HVIGDFMQSMGVLVAAYILY----------F-----------KP---------------------EYKYVDPICTFVFSILVLGTTLTILRDVILVLMEGTPKGVD--FTAVRDLLLSVEGVEALHSLHIWALTVAQPVLSVHIAI---------AQNTDAQAVLKTASSRLQGKFHFHTVTIQIEDYSED------------------------------MKDCQACQGPSD----------------------------------------------------------------------------------------------------------------------
SLC30A3   MEPS---------------------------------------------------PAAGGLETTRLVSPRDR-GG------------------------------------------------------AGGS----LRL--------------------------------------------------KSLFTEPSE--------------------------------------------------------------------------------------------PLP----------------------------------------------------------------------------------------------------------EESKPVEMPF----------------------HHCHRDPLPPPGLTP------------------ERLHARRQ-------------LYAACAVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADV----------------------------------------GSMMGSLFSLWLSTRPATRTMT--FGWHRSETLGALASVVSLWMV-TGILLYLAFVRLLHSD--------YHIEGGAMLL-TASIAVCANLLMAFVLHQ---------------------AGPPHSHG-SRGAEYAPLE--------------------------------------------------------EGPEEPLP------------------LGNTSVRAAFV-----HVLGDLLQSFGVLAASILIY----------F-----------KP---------------------QYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVG--FEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAI---------DSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPE------------------------------MAQCLRCQEPPQA---------------------------------------------------------------------------------------------------------------------
SLC30A4   MAGSGA-------------------------------------WKRLKSML-RKDDAPLFLNDTSAFDFSDEAGD------------------------------------------------------EGLSRFNKLRVV------------------------------------------------VADDGSEAPER-------------------------------------------------------------------------------------------PVNG-----------------------------AHP---------------TLQADDD------------------------------------------------SLLDQDLPLTNSQL--------------SLKVDSCDNCSKQRE-----IL------------------KQRKVKAR-------------LTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDL----------------------------------------SAIILTLLALWLSSKSPTKRFT--FGFHRLEVLSAMISVLLVYIL-MGFLLYEAVQRTIHMN--------YEINGDIMLI-TAAVGVAVNVIMGFLLNQ---------------------SGHRHSHS-HSLPSNSPTRG-------------------------------------------------------SGCERNHG------------------QDSLAVRAAFV-----HALGDLVQSVGVLIAAYIIR----------F-----------KP---------------------EYKIADPICTYVFSLLVAFTTFRIIWDTVVIILEGVPSHLN--VDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLI-------PGSSSKWEEVQSKANHLLLNTFGMYRCTIQLQSYRQE-----------------------------VDRTCANCQSSSP----------------------------------------------------------------------------------------------------------------------
SLC30A5   MEEKYGGDV-----------LAGPGGGGGLGPVD-------VPSARLTKYI-VLLCFTKFLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQALSHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSKCARYGSFPIFI---SALLFGNFWTHPITDQL----RAMNKAAHQESTEHVLSGGVVVSAIFFILSANILSSPSKRGQKGTLIGYSPEGTPLY--------------NFMGDAFQHSSQS-------IPR--------FIKESLKQILEESDSRQ-------------IFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDC----------------------------------------SALVMGLFAALMSRWKATRIFS--YGYGRIEILSGFINGLFLIVI-AFFVFMESVARLIDPP---------ELDTHMLTP-VSVGGLIVNLIGICAFSH----------------------AHSHAHGASQGSCHS------------SDHSHSH-------HMHGHSDHGHGHSHGS-----------------AGGGMNAN-----------------------MRGVFL-----HVLADTLGSIGVIVSTVLIE---------QF----------------------------------GWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQV---------TSDVLEQRIVQQVTGILKDA-GVNNLTIQVEKEAYF------------------------------------------------------------------QHMSGLSTGFHD------------------VLAMTKQM--------------ESM-------------------------KYCKDGTYIM----
SLC30A6   ------------------------------------------------------------MGTIHLFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPQR--------------SFFGK---------------------------LLREFRLVAADRRSWK-------------ILLFGVINLICTGFLLMWCSSTNSIALTAYTYLTIFDLFRDGVSPFWLGWSQTPDLKWSTHLGLPKCWDNRRELPCLSNSLMTCLISYWVTLRKPSPVYS--FGFERLEVLAVFASTVLAQLG-ALFILKESAERFLEQP---------EIHTGRLLV-GTFVALCFNLFTMLSIRNKPFAYV------------------------SEAASTSWLQE-----------------------------HVADLSRSL-----------------CG------------IIP-------------GLSSIFLPRMNPFVLIDLAGAFALCITYMLIE-------------------------------IN------------NYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRI---------RRDANEQMVLAHVTNRLYTL--VSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHVIPMPLLKGTDDLNPVTSTPAK---------------PSSPPPEFSFNTPGKNVN--------------------PVILLNTQTRPYGFGLNHGHTPYSSMLNQGLGVPGIGATQGLRTGFTNIPSRYGTNNRIGQPRP-
SLC30A7   -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPLS---------------------------------------------------IKDD----------------------------------------------------EYKP---PKF--------------NLFGK---------------------------ISGWFRSILSDKTSRN-------------LFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDS----------------------------------------TAILAGLAASVISKWRDNDAFS--YGYVRAEVLAGFVNGLFLIFT-AFFIFSEGVERALAPP---------DVHHERLLL-VSILGFVVNLIGIFVFKH---------------------GGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHA-HGHGHFHSH-----------------DGPSLKET------TGPSRQ----------ILQGVFL-----HILADTLGSIGVIASAIMMQ---------NF----------------------------------GLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIV---------APDADARWILSQTHNIFTQA-GVRQLYVQI-----------------------------------------------------------------------------------D------------------FAAM------------------------------------------------------------
SLC30A8   ME---------------------------------------------------------FLERTYLVNDKAA-KM------------------------------------------------------YAFT----LE------------------------------------------------------SVELQQK-------------------------------------------------------------------------------------------PVN----------------------------------------------------------------------------------------------------------KDQCPRERPE---------------ELESGGMYHCHSGSKPTEKGAN------------------EYAYAKWK-------------LCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDL----------------------------------------TSFLLSLFSLWLSSKPPSKRLT--FGWHRAEILGALLSILCIWVV-TGVLVYLACERLLYPD--------YQIQATVMII-VSSCAVAANIVLTVVLHQ---------------------RCLGHNH----KEVQA---------------------------------------------------------------------------------------NASVRAAFV-----HALGDLFQSISVLISALIIY----------F-----------KP---------------------EYKIADPICTFIFSILVLASTITILKDFSILLMEGVPKSLN--YSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVAT---------AASRDSQVVRREIAKALSKSFTMHSLTIQMESPVDQ------------------------------DPDCLFCEDPCD----------------------------------------------------------------------------------------------------------------------
SLC30A9   MLPGLAAAAAHRCSWSSLCRLRLRCRAAACNPSDRQEWQNLVTFGSFSNMVPCSHPYIGTLSQVKLYSTNVQKEG------------------------------------------------------QGSQ---TLRV-------------------------------------------------EKVPSFETAEG----------------------------------------------------------------------------IGTELKA--------PLK------------------------------QEPLQVRVKAVLKKREYGSKYTQNNFITGVRAINE---------------------FCLKSSDLE------QLRKIRRRSPHEDTESFTVYLRSDVEAKSLEVWGSPEALAREKKLRKEAEIEYRERLFRNQKILREYRDFLGNTKPRSRTASVFFKGPGKVVMVAICINGLNCFFKFLAWIYTGSASMFSEAIHSLSDT----------------------------C--NQ------------GLLALGISKSVQTPDPSHPYGFSNMRYISSLISGVGIFMMGAGLSWYHGVMGLLHPQPIESLLWAYCILAGSLVSEGATLLVAVNEL--------------------RRN--------------ARAKGMSFYKYVM---------------------------ESRDPSTNV-----------------------------------------------------------ILLEDTAAVLGVIIAATCMGLT-------SI---------TGNP--------------LYDSL--GSLGVGTLLGMVSAFLIYTNTEALLGRSIQ------PEQVQ----RLTELLENDPSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEKQDFDQMLQEIQEVKTPE--------ELETFMLK-------------------H------------------------------------------GENIIDTLGAEVDRLE--KELKKRNPE-----VRHVDLEIL---------------------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC30A4 64 G/R 0.000198818 rs148549828
-- SLC30A4 97 N/S 0.000652098 rs143806143
-- SLC30A4 344 I/V 0.00150178 rs201823030

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data