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Basic
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Structure
Seq./Align.
Variant
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Pathway
Disease

Detail Data SLC26A8


Basic description
Gene Name SLC26A8
Protein Name Testis anion transporter 1 (Anion exchange transporter) (Solute carrier family 26 member 8)
Family SLC26
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 5 8 0 5 9 0 6 0 0 6 1 0 6 2 0 6 3 0 6 4 0 6 5 0 6 6 0 6 7 0 6 8 0 6 9 0 7 0 0 7 1 0 7 2 0 7 3 0 7 4 0 7 5 0 7 6 0 7 7 0 7 8 0 7 9 0 8 0 0 8 1 0 8 2 0 8 3 0 8 4 0 8 5 0 8 6 0 8 7 0 8 8 0 8 9 0 9 0 0 9 1 0 9 2 0 9 3 0 9 4 0 9 5 0 9 6 0 9 7 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550        560        570        580        590        600        610        620        630        640        650        660        670        680        690        700        710        720        730        740        750        760        770        780        790        800        810        820        830        840        850        860        870        880        890        900        910        920        930        940        950        960        970 
MAQLERSAIS GFSSKSRRNS FAYDVKREVY NEETFQQEHK RKASSSGNMN INITTFRHHV QCRCSWHRFL RCVLTIFPFL EWMCMYRLKD WLLGDLLAGI SVGLVQVPQG LTLSLLARQL IPPLNIAYAA FCSSVIYVIF GSCHQMSIGS FFLVSALLIN VLKVSPFNNG QLVMGSFVKN EFSAPSYLMG YNKSLSVVAT TTFLTGIIQL IMGVLGLGFI ATYLPESAMS AYLAAVALHI MLSQLTFIFG IMISFHAGPI SFFYDIINYC VALPKANSTS ILVFLTVVVA LRINKCIRIS FNQYPIEFPM ELFLIIGFTV IANKISMATE TSQTLIDMIP YSFLLPVTPD FSLLPKIILQ AFSLSLVSSF LLIFLGKKIA SLHNYSVNSN QDLIAIGLCN VVSSFFRSCV FTGAIARTII QDKSGGRQQF ASLVGAGVML LLMVKMGHFF YTLPNAVLAG IILSNVIPYL ETISNLPSLW RQDQYDCALW MMTFSSSIFL GLDIGLIISV VSAFFITTVR SHRAKILLLG QIPNTNIYRS INDYREIITI PGVKIFQCCS SITFVNVYYL KHKLLKEVDM VKVPLKEEEI FSLFNSSDTN LQGGKICRCF CNCDDLEPLP RILYTERFEN KLDPEASSIN LIHCSHFESM NTSQTASEDQ VPYTVSSVSQ KNQGQQYEEV EEVWLPNNSS RNSSPGLPDV AESQGRRSLI PYSDASLLPS VHTIILDFSM VHYVDSRGLV VLRQICNAFQ NANILILIAG CHSSIVRAFE RNDFFDAGIT KTQLFLSVHD AVLFALSRKV IGSSELSIDE SETVIRETYS ETDKNDNSRY KMSSSFLGSQ KNVSPGFIKI QQPVEEESEL DLELESEQEA GLGLDLDLDR ELEPEMEPKA ETETKTQTEM EPQPETEPEM EPNPKSRPRA HTFPQQRYWP MYHPSMASTQ SQTQTRTWSV ERRRHPMDSY SPEGNSNEDV  
CCHHHHHHCC CCCCCCCCCC CEEEEECCCC CHHHHHHHCC CCCCCCCCCC CCHHHHHHHH CCCCCHHHHH HHHHHHCHHH HHHCCCCHHH HHHHHHHHHH HHHHHHCHHH HHHHHHHCCC CCHHHHHHHH HHHHHHHHHH HCCCHHHHHH HHHHHHHCHH HEEECCCCCC CCCCCCCCCC CCCCHHHHCC HHHHHHHHHH HHHHHHHHHH HHHHHHCCHH HHHCCHHHHH HHHHHHHHHH HHHHHHHHHC CCCCCCCCHH HHHHHHHHHH HHCCCCHHHH HHHHHHHHHH HHHHHHHHHH CCCCCCCHHH HHHHHHHHHH HHHHHHHCHH CCCCCCCCCC CCCCCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC HHHHHHHHHH HHHHHCCCCC CCCCHHHHHH HHHCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HCHHHHHHHH HCCHHHHHHH HHHHHHHHHH CHHHHHHHHH HHHHHHHHHH HHHCCEEEEE ECCCCCCEEE HHHHCCCEEC CCEEEEEECC CCCCCCHHHH HHHHHHHHHC CCCCCCEEEE EECCCCCCCC CCHHHHHHHH HHCCCCCCCC HHHCHHHHHC CCCCCCCCCC EEEECCCHHC CCCCCCCCCC CCCCCCCCCC CCCCCCCHHC CCCCCCCCCC CCCCCCCCCC HHCCCCCCCC CCCCCCCCCC CCEEEECCCE EEEECHHHHH HHHHHHHHHH HCCCEEEEEC CCHHHHHHHH HCCCCCCCCC CCEEECCHHH HHHHHHHCCC CCCCCCCCCC CHHHHHCCCC CCCCCCCCHH HHHHCCCCCC CCCCCCCCCC CCCCCCCCHH HHHCHHHHHC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCHHCCC CCCCCCCCCC CCCCCCCCCH HHCCCCCCCC CCCCCCCCCC
[Overview] SLC26A1 SLC26A10 SLC26A11 SLC26A2 SLC26A3 SLC26A4 SLC26A5 SLC26A6 SLC26A7 SLC26A8 SLC26A9 
SLC26A1   --------MDESPEPLQQGRGPVP--------------------------------VRRQRPAPRGLRE------------------MLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--LQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLC-LMVGQVV------------DRELQLAGFDPSQDGLQPG--ANSSTL--------NGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTS---TVCLAVLLAA---KELSDRYRHRLRVPLPT---------------ELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVA------------LALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD-----AGCMAARRKEGGSE----------------------------------------------------------------------------------TGVGEGGPAQGEDLG----------------PVSTRAALVPAAA-----------GFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGA----LGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHR---ELE------------------ATDAHL-----------------------------------------------------------------------------------------------------------------------------------------------
SLC26A10  -----------------------------------MRLDL-------------ASLMSAPKSLGSAFKS-WRLDKAPSPQHT-----------------------------FPSTS-IP-------------------------GMAFALLAS--VPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILS-LMTG----SAVERLVPE-----------------PLVG-----------------NLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTIS---ALSLALLVPV---KELNVRFRDRLPTPIPG---------------EVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLP------------IALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLL-----------------------------------------------------------QVPGLCILSYPTPLYFGTRGQFRCNLEWHLGLGE---------------GEK----------------------------------------------------------------------------------ETSKPDG------------------------PMVAVAE-----------------PVRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLL-----DRVTPDQLFVSVQDAAAYALGSLLRGSSTRS--GSQEALGCGK----------------------------------------------------------------------------------------------------------------------------------------------------------
SLC26A11  ----------------------MPSS---------------------------VTALGQARSSGPGMAP-------------------------SACCCSPA----ALQRRLPILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAG--LPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMS-LLVSFYT-----------------------FHE---------------PAY---------------------AVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQ----NIPRPFFLQVYHTFLRIAETRVGDAVLG---LVCMLLLLVL---KLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAVAPLF-DTKIFRTLWRVKRLDLLPLCVTFLLC-FWEVQYGILAGALVSLLMLLHSAARPETKV--------------------SEGPVLVLQPASGLSFPAMEALREEILSRA-------------------------------------------------------------------------------------------------------------------------------------------------------LEVSPP----RCLVLECTHVCSIDYTVVLGLGELLQDFQK----QGVALAFVGLQVPVLRVLLSA--------D-LKGFQYFSTLEEAEKHLRQEPG---------------------TQPYNIREDSILDQKVALLKA-----------------------------------------------------------------------------------------------------------------------------------
SLC26A2   MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESS-TDFKQFETNDQCRPYHRILIERQEKSDTNFKE------------------FVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAG--QEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLC-LMIGETV------------DRELQKAGYDNAHSAPSLGMVSNGSTL--------LNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITS---LLCLLVLLPT---KELNEHFKSKLKAPIPI---------------ELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIA------------ISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKI--KE----------------------------------------------------------------------------------KVVTLGG-IQDE--------------------MSVQLSHDPLE-------------LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEA----IGIQVLLAQCNPTVRDSLTNGEYCKK-----EEENLLFYSVYEAMAFAEVSKN---QKGVCVPN---------GLSLSSD--------------------------------------------------------------------------------------------------------------------------------------------------
SLC26A3   ---------------MIEPFGN-------------------------------QYIVARPVYSTNAFEE--NHKKTGRHH------KTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVD--IPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILS-MMVGLAVSGAVSKAVP---DR--------------------NATTLGLPN--NSNNSSLLD---DERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTA---LIVLLVVSIV---KEINQRFKDKLPVPIPI---------------EFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFG------------IAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKI--RK-----------------------------LQK-------QGLLQ---VTPKGFI---CTVDTI--KDSDEELDNN-------QIEVLDQPINTTDLPFHIDWNDDL-------PL---------------NIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIR----IKVDVYIVGTDDDFIEKLNRYEFF-DGE---VKSSIFFLTIHDAVLHILMKKDYSTSKFN--PSQEKDGKIDFTINTNGGLRNRVYEVPVE----------------------TKF--------------------------------------------------------------------------------------------------------------
SLC26A4   ---------------MAAPGGRSEP---PQLPEYSC-----------------SYMVSRPVYSELAFQQ--QHERRLQER------KTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAA--VPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVS-LMVG----SVVLSMAP---DEHFLVSS-------------SNGTVL---------NTTMIDTAARDTARVLIASALTLLVGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVEIFQNIGDTNLADFTAG---LLTIVVCMAV---KELNDRFRHKIPVPIPI---------------EVIVTIIATAISYGANLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFS------------IAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVKILRFSSPIFYGNVDGFKKCIKSTVGFDAIRVYNKRLKALRKI--QK-----------------------------LIK-------SGQLR---ATKNGIISDAVSTNNA--FEPDEDIED---------LEELDIP--TKEIEIQVDWNSEL-------PV---------------KVNVPKVPIHSLVLDCGAISFLDVVGVRSLRVIVKEFQR----IDVNVYFASLQDYVIEKLEQCGFF-DDN---IRKDTFFLTVHDAILYLQNQVK----------SQEGQGSILETITLIQDCKDTL-EL-IE----------------------TELTEE-----------ELDVQDEAM-----------RTLAS-----------------------------------------------------------------------
SLC26A5   -------------MDHAEEN---------EILAATQ-----------------RYYVERPIFSHPVLQE--------RLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA--VPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVIS-LMIG----GVAVRLVP---DDIVIPGG-------------VNATNG---------------TEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSL------GVGLMVFGLLLGGKEFNERFKEKLPAPIPL---------------EFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIA------------IAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKY--AK-----------------------------------------------------------------EVGNANMANA-------TVVKADAEVDGEDATKPEEEDGEVK----YPPIVIKST-FPEEM---QRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGD----VGIYVYLAGCSAQVVNDLTRNRFF-ENP---ALWELLFHSIHDAVLGSQLREALAEQEASAPPSQE------------DLEPNATPATPEA---------------------------------------------------------------------------------------------------------------------------------------
SLC26A6   -------------MGLADASGPRDT---QALLSATQAMDL----------RRRDYHMERPLLNQEHLEELGRWGSAPRTH-----------QWRTWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMS-VMVG----SVTESLAPQALNDSMI-----------------NET-------------------ARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLL------NDKLQQQLPMPIPG---------------ELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFT------------IAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ--EQL------------------------KLKQLQK-------EEKLRKQAASPKGASVS-INVNTSLEDMRSNNVEDC-------KMMQVSSGDKMEDATANGQEDS-------------KAP-DGSTL---KALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE----IEVEVYMAACHSPVVSQLEAGHFF-DAS---ITKKHLFASVHDAV-------TFALQ-----------------------HPRPVPDSPVSV---------------------TRL--------------------------------------------------------------------------------------------------------------
SLC26A7   -------------------------------------------------------MTGAKRKKKSMLWS--------KMH------TPQCEDIIQWCR-----------RRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSS--VHPVFGLYGSLFPAIIYAIFGMGHHVATGTFALTS-LISA----NAVERIVPQN---------------------MQNLTTQ--------SNTSVLGLSDFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLS---LLSIVVLVLV---KELNEQFKRKIKVVLPV---------------DLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFG------------VALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICFAANVGLLFGVVCTIAIVIGR--FPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKIISINNPLVFLNAKKFYTDLMNMI--------------------QK----------------------------------------------------------------ENACNQPLDDISKCEQNTLLNSLSNGNCNEEASQSCPNEKCY-----------------------------------LILDCSGFTFFDYSGVSMLVEVYMDCKG----RSVDVLLAHCTASLIKAMTYYGNL-----D-SEKPIFFESVSAAISHIHSNKN---------------------LSKLSDHSEV----------------------------------------------------------------------------------------------------------------------------------------------
SLC26A8   ---------------MAQLERSAISG----FSSKSRRNSF-------------AYDVKREVYNEETFQQ--EHKRKASSSGNMNI-NITTFRHHVQCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLIN------VLKVSPFN-NGQLVMGSF-----------VKNEFSA--PSYLMGYNKS-----------LSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSI------LVFLTVVVALRINKCIRISF-NQYPIEFPM---------------ELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFS------------LSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDM---------VKVPLKE--EEIFSLFNSSDTNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTV-----SSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLP--SVHTIILDFSMVHYVDSRGLVVLRQICNAFQN----ANILILIAGCHSSIVRAFERNDFF-DAG---ITKTQLFLSVHDAVLFALSRKVIGSSELSIDESET---VIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSYSPEGNSNEDV
SLC26A9   ---------------MSQP--------------------------------RPRYVVDRAAYSLTLFDD--EFEKKDRTY-------PVGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLAN--LPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVIS-ILVG----NICLQLAP---ESKFQVFN--------------NAT-----------NESYVDTAAMEAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLV------KELNARYMHKIRFPIPT---------------EMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFS------------LAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ--EKR------------------------RMRPTQQ-------RRSLF-------------MKTKTVSLQELQQDFENAPPTDP-NNNQTPANGTSVSYITFSPDSSSPAQS---EPPASAEAPGEPSDM---LASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK----IGVKVFLVNIHAQVYNDISHGGVFEDGS---LECKHVFPSIHDAVLFAQANAR------DVTPGHNFQGAP-------GDAELSLYDSEEDI---------------------RSY---------------WDLEQEMFGSM-----FHAETLTAL----------------------------------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC26A8 5 R/Q 0.000579512 rs186526918
-- SLC26A8 6 G/R 0.000126283 rs745343891
-- SLC26A8 7 S/N 0.000171476 rs201560074
-- SLC26A8 7 L/P 0.000638883 rs145896455
-- SLC26A8 15 K/E 0.000319441 rs373938103
-- SLC26A8 28 Y/H 0.000207987 rs769400873
-- SLC26A8 43 R/Q 0.000182534 rs567862507
-- SLC26A8 49 G/S 0.000193209 rs534357096
-- SLC26A8 69 R/G 0.349253 rs9368897
-- SLC26A8 71 R/Q 0.000187635 rs116146081
-- SLC26A8 73 V/M 0.234002 rs743923
-- SLC26A8 73 D/E 0.000124221 rs552212108
-- SLC26A8 74 P/A 0.000125547 rs530686552
-- SLC26A8 83 M/T 0.000141815 rs549200030
-- SLC26A8 84 C/R 0.000356607 rs199880055
-- SLC26A8 85 P/S 0.000168265 rs569878762
-- SLC26A8 87 R/Q 0.000309192 rs140210148
-- SLC26A8 89 K/R 0.000357129 rs749769087
-- SLC26A8 148 I/V 0.123502 rs17713154
-- SLC26A8 223 Y/C 0.000332908 rs148004355
-- SLC26A8 230 S/N 0.119583 rs17707331
-- SLC26A8 290 A/S 0.000294368 rs141811686
-- SLC26A8 379 I/V 0.00151989 rs550588031
-- SLC26A8 439 M/L 0.000139594 rs182055577
-- SLC26A8 464 S/R 0.000111371 rs201957816
-- SLC26A8 498 I/V 0.000489661 rs116528901
-- SLC26A8 542 N/S 0.00111842 rs115224596
-- SLC26A8 545 R/Q 0.000199108 rs142348124
-- SLC26A8 602 Q/P 0.000175258 rs186939060
-- SLC26A8 609 C/F 0.000650304 rs566209205
-- SLC26A8 618 P/L 0.00028792 rs149456040
-- SLC26A8 627 R/Q 0.000135404 rs566366898
-- SLC26A8 639 I/V 0.334652 rs2295852
-- SLC26A8 692 N/I 0.000174978 rs200648238
-- SLC26A8 731 V/I 0.000469308 rs559176786
-- SLC26A8 734 V/M 0.00117732 rs138344479
-- SLC26A8 748 A/G 0.000131218 rs375415581
-- SLC26A8 768 A/S 0.00020681 rs564834835
-- SLC26A8 809 D/N 0.00108166 rs114153657
-- SLC26A8 812 E/K 0.000230653 rs142724470
-- SLC26A8 816 R/Q 0.0067854 rs35886585
-- SLC26A8 912 P/S 0.00965859 rs61741366
-- SLC26A8 936 M/K 0.000190869 rs145617232
-- SLC26A8 965 N/S 0.000354816 rs191020229

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data