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Detail Data SLC25A45
Basic description
Gene Name | SLC25A45 |
---|---|
Protein Name | Solute carrier family 25 member 45 |
Family | SLC25 |
Category | - |
Reaction name | - |
Reaction | - |
[Overview]
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 MPVEEFVAGW ISGALGLVLG HPFDTVKVRL QTQTTYRGIV DCMVKIYRHE SLLGFFKGMS FPIASIAVVN SVLFGVYSNT LLVLTATSHQ ERRAQPPSYM HIFLAGCTGG FLQAYCLAPF DLIKVRLQNQ TEPRAQPGSP PPRYQGPVHC AASIFREEGP RGLFRGAWAL TLRDTPTVGI YFITYEGLCR QYTPEGQNPS SATVLVAGGF AGIASWVAAT PLDMIKSRMQ MDGLRRRVYQ GMLDCMVSSI RQEGLGVFFR GVTINSARAF PVNAVTFLSY EYLLRWWG CCHHHHHHHH HHHHHHHHHC CCHHHHHHHH HCCCCCCCHH HHHHHHHHHC CHHHHHCCCH HHHHHHHHHH HHHHHHHHHH HHHHHHCCCC CCCCCCCCHH HHHHHHHHHH HHHHHHHCCH HHHHHHHHHC CCCCCCCCCC CCCCCCHHHH HHHHHHHHCH HHHHCCHHHH HHHHCHHHHH HHHHHHHHHH HCCCCCCCCC HHHHHHHHHH HHHHHHHHHC CHHHHHHHHH HCCCCCCCCC CHHHHHHHHH HHHCHHHHCC CHHHHHHHHH HHHHHHHHHH HHHHHHHC
[Overview]
SLC25A1 ----------------------------------------------------------------------------------MPAP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAPRALAAAAPASG-----------------------------------------KAKLTHPGKAILA-------------------------------------------------------G----------GLAGGIEI-CITFPTEYVKTQLQLDERS-------------------------------------------------------HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG------------RLDSTRGLLCGLGAGVAEAVV---VVCPMETIKVKFI--------HD------------------------------QTSPNPKY-RGFF------HGVREI-VREQ--GL----------KGTYQGLTATVLKQGSNQ-AIRFFVMTSLRNWYRGD------NPNK--------PMNPLIT-----GVFGAIA-------------GAASVFGNTPLDVIKTRMQGLEAHK-----------YR---------NTWDCGLQ-ILKKE----GLK-AFYKGTVPRLGRVCLDVAIVFVI---YD-----------------------------------EVVKLLNKVWKTD------------------------------------------------------------------ SLC25A10 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAEA-----------------------------------------------------RVSRWYF-------------------------------------------------------G----------GLASCGAA-CCTHPLDLLKVHLQTQQE------------------------------------------------VKLR-----------MTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVA-KGSQG----------PLPFHEKVLLGSVSGLA-GGF---VGTPADLVNVRMQ-------------NDVKLP----------------------QGQRRNY-AHAL------DGLYRV-AREE--GL----------RRLFSGATMASSRGALVT-VGQLSCYDQAKQLV----LSTGYL-----------SDNIFTH-----FVASFIAAAGD----EPPPQGGCATFLCQPLDVLKTRLMNSK---------GE---YQ---------GVFHCAVE-TAKL-----GPL-AFYKGLVPAGIRLIPHTVLTFVF---LE-----------------------------------QLRKNFGIKVPS------------------------------------------------------------------- SLC25A11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATASAGAGGIDG--------------------------------------KPRTSPKSVKFLF-------------------------------------------------------G----------GLAGMGAT-VFVQPLDLVKNRMQLSGEGA------------------------------------------------------KTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLT-GADGT----------PPGFLLKAVIGMTAGAT-GAF---VGTPAEVALIRMT-------------ADGRLP----------------------ADQRRGY-KNVF------NALIRI-TREE--GV----------LTLWRGCIPTMARAVVVN-AAQLASYSQSKQFL----LDSGYF-----------SDNILCH-----FCASMIS-------------GLVTTAASMPVDIAKTRIQNMRMID------GKPE-YK---------NGLDVLFK-VVRYE----GFF-SLWKGFTPYYARLGPHTVLTFIF---LE-----------------------------------QMNKAYKRLFLSG------------------------------------------------------------------ SLC25A12 ------------------MAVKVQTTKRGDPHELRNIFLQ---Y--ASTEVDGERYMTP--EDFVQ-----RYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAI----------RYGQVTP-------------------LEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQ--SPGLGRPIWLQIAESAYRFTLG----------SVAGAVGA-TAVYPIDLVKTRMQNQRGSGS---------------------------------------------------VVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDG------------SVPLPAEVLAGGCAGGS-QVI---FTNPLEIVKIRLQVAGEI-----------------------------------TTGP-----RVSA-----LNVLRDL-------GI----------FGLYKGAKACFLRDIPFS-AIYFPVYAHCKLLL---------ADENGH------VGGLNL------LAAGAMA-------------GVPAASLVTPADVIKTRLQVAARA-------GQTT-YS---------GVIDCFRK-ILREE----GPS-AFWKGTAARVFRSSPQFGVTLVT---YE-----------------------------------LLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ SLC25A13 -----------------MAAAKVALTKRADPAELRTIFLK---Y--ASIEKNGEFFMSP--NDFVT-----RYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQ----------KFGQVTP-------------------MEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLG----------SVAGAVGA-TAVYPIDLVKTRMQNQRSTGS---------------------------------------------------FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG------------SVPLAAEILAGGCAGGS-QVI---FTNPLEIVKIRLQVAGEI-----------------------------------TTGP-----RVSA-----LSVVRDL-------GF----------FGIYKGAKACFLRDIPFS-AIYFPCYAHVKASF---------ANEDGQ------VSPGSL------LLAGAIA-------------GMPAASLVTPADVIKTRLQVAARA-------GQTT-YS---------GVIDCFRK-ILREE----GPK-ALWKGAGARVFRSSPQFGVTLLT---YE-----------------------------------LLQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFK-PSVSTSK---AIGGGP SLC25A14 -------------------------------------------------------------------------------MGIFPGIILI------------------------------------------------------------------------FLRVKF-----------------------------------------------------------------ATAA------------------------------VIVSGHQKSTTVSHEMSGL-------------------------------------------NW---KPFVY-------------------------------------------------------G----------GLASIVAE-FGTFPVDLTKTRLQVQGQSID---------------------------------------------ARF-----KEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDE----------TLLI--NMICGVVSGVI-SST---IANPTDVLKIRMQ-------------AQGS-LF---------------------QG-------SMI------GSFIDI-YQQE--GT----------RGLWRGVVPTAQRAAIVV-GVELPVYDITKKHL----ILSGMM-----------GDTILTH-----FVSSFTC-------------GLAGALASNPVDVVRTRMMNQRAIV------GHVDLYK---------GTVDGILK-MWKHE----GFF-ALYKGFWPNWLRLGPWNIIFFIT---YE-----------------------------------QLKRLQI------------------------------------------------------------------------ SLC25A15 -------------------------------------------------------------------------------MKSNPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQAAIDLTA-------------------------------------------------------G----------AAGGTACV-LTGQPFDTMKVKMQT-----------------------------------------------------------FPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAK------L-SDLQNAAAGSFASAF-AAL---VLCPTELVKCRLQTMYEM---------E-------------------------TSGKIAKS-QNTV-----WSVIKSI-LRKD--GP----------LGFYHGLSSTLLREVPGY-FFFFGGYELSRSFF---------A-SGRSK---DELGPVPL------MLSGGVG-------------GICLWLAVYPVDCIKSRIQVLSMS-------GKQ---A---------GFIRTFIN-VVKNE----GIT-ALYSGLKPTMIRAFPANGALFLA---YE-----------------------------------YSRKLM---------------------------------------------------MNQLEAY--------------- SLC25A16 ------------------MAAATAAAALA-------------------------------------------------AADPPPAMPQAAGAGGPTTR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDFYW------------------------------------------------------LRSFLA-------------------------------------------------------G----------GIAGCCAK-TTVAPLDRVKVLLQAH---------------------------------------------------------NHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHV------------HRLMAGSMAGMT-AVI---CTYPLDMVRVRLA-------------F--------------------------QVKGEHSY-TGII------HAFKTIYAKEG--GF----------FGFYRGLMPTILGMAPYA-GVSFFTFGTLKSVGLSH-A-----PTLLGRPSSDNPNVLVLKTH-VNLLCGGVA-------------GAIAQTISYPFDVTRRRMQL-GTV-------LPEFEKC---------LTMRDTMKYVYGHH----GIRKGLYRGLSLNYIRCIPSQAVAFTT---YE-----------------------------------LMKQFF-HLN--------------------------------------------------------------------- SLC25A17 -------------------------------------------------------------------------------MAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLSYESLVHAVA-------------------------------------------------------G----------AVGSVTAM-TVFFPLDTARLRLQVDEKRK------------------------------------------------------SKTTHMVLLE----IIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQ-------------HSTTGKDLVVGFVAGVV-NVL---LTTPLWVVNTRLK-------------LQGAKFRN-------------------EDIVPTNY-KGII------DAFHQI-IRDE--GI----------SALWNGTFPSLLL--VFNPAIQFMFYEGLKRQL----LKKRMKLSSLDV-----------------FIIGAVA-------------KAIATTVTYPLQTVQSILRFGRHRL-----NPENR-TL---------GSLRNILY-LLHQRVRRFGIM-GLYKGLEAKLLQTVLTAALMFLV---YE-----------------------------------KLTA--------------------------------------ATFTVMGLKRAHQH----------------------- SLC25A18 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHQDLSIT------------------------------------------------------AKLIN-------------------------------------------------------G----------GVAGLVGV-TCVFPIDLAKTRLQN-QH--------------------------------------------------------GKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGM------------QRNLKMEMLAGCGAGMC-QVV---VTCPMEMLKIQLQDAGRLAVHH-----QGSASAP----STSRSY---------TTGSASTHRRPSA-----TLIAWEL-LRTQ--GL----------AGLYRGLGATLLRDIPFS-IIYFPLFANLNNLG---------FNELAG------KASFAHS-----FVSGCVA-------------GSIAAVAVTPLDVLKTRIQTLKKGL------GEDM-YS---------GITDCARK-LWIQE----GPS-AFMKGAGCRALVIAPLFGIAQGV---Y----------------------------------------------------------------------------------FIGIGERI---LKCFD----------------- SLC25A19 -------------------------------------------------------MV---------------------GYDPKP-----------------------------------------------------------------------------------------------------------------------DG--------------------------------------------------------------------RNNTK------------------------------------------------------FQVAVA-------------------------------------------------------G----------SVSGLVTR-ALISPFDVIKIRFQLQHERLSRS--------------------------------------------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVH-----RGSVY-----DAREFSVHFVCGGLAACM-ATL---TVHPVDVLRTRFA-------------A---------------------------QGEPKVY-NTLR------HAVGTM-YRSE--GP----------QVFYKGLAPTLIAIFPYA-GLQFSCYSSLKHLYKWA-IPA----------EGKKNENL------QNLLCGSGA-------------GVISKTLTYPLDLFKKRLQVGGFEHARAAFGQ-VRRYK---------GLMDCAKQ-VLQKE----GAL-GFFKGLSPSLLKAALSTGFMFFS---YEF---FC-----------------------------NVFHCMNRTASQR------------------------------------------------------------------ SLC25A2 -------------------------------------------------------------------------------MKSGPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQAAIDLTA-------------------------------------------------------G----------AAGGTACV-LTGQPFDTIKVKMQT-----------------------------------------------------------FPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAK------L-SDLQTAAAGSFASAF-AAL---ALCPTELVKCRLQTMYEM---------E-------------------------MSGKIAKS-HNTI-----WSVVKGI-LKKD--GP----------LGFYHGLSSTLLQEVPGY-FFFFGGYELSRSFF---------A-SGRSK---DELGPVHL------MLSGGVA-------------GICLWLVVFPVDCIKSRIQVLSMY-------GKQ---A---------GFIGTLLS-VVRNE----GIV-ALYSGLKATMIRAIPANGALFVA---YE-----------------------------------YSRKMM---------------------------------------------------MKQLEAY--------------- SLC25A20 -------------------------------------------------------------------------------MADQPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PISPLKNLLA-------------------------------------------------------G----------GFGGVCLV-FVGHPLDTVKVRLQTQPPSLP----------------------------------------------------GQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK----HPEDV------L-SYPQLFAAGMLSGVF-TTG---IMTPGERIKCLLQ----I---------Q-------------------------ASSGESKY-TGTL------DCAKKL-YQEF--GI----------RGIYKGTVLTLMRDVPAS-GMYFMTYEWLKNIF---------TPEGKRV---SELSAPRI------LVAGGIA-------------GIFNWAVAIPPDVLKSRFQTAPPG-------KYP---N---------GFRDVLRE-LIRDE----GVT-SLYKGFNAVMIRAFPANAACFLG---FE-----------------------------------VAMKFLN-----------------WA-------------------------------TPNL------------------ SLC25A21 -------------------------------------------------------------------------------MSAKPE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSLVREASRQIVA-------------------------------------------------------G----------GSAGLVEI-CLMHPLDVVKTRFQIQRCAT------------------------------------------------------DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVS-------------LSPALTFAIAGLGSGLT-EAI---VVNPFEVVKVGLQ-------------ANRNTFAE-------------------Q---PST-----V------GYARQI-IKKEGWGL----------QGLNKGLTATLGRHGVFN-MVYFGFYYNVKNMIP---VNKDPILEFWRK-----------------FGIGLLS-------------GTIASVINIPFDVAKSRIQ-GPQPV-----PGEIK-YR---------TCFKTMAT-VYQEE----GIL-ALYKGLLPKIMRLGPGGAVMLLV---YE-------------------------------------------------------------------------------YTYSWLQENW------------------------- SLC25A22 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADKQISLP------------------------------------------------------AKLIN-------------------------------------------------------G----------GIAGLIGV-TCVFPIDLAKTRLQNQQN--------------------------------------------------------GQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQ------------KLTLLKEMLAGCGAGTC-QVI---VTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQ----GGAQPS---------VEAPAAP--RPTA-----TQLTRDL-LRSR--GI----------AGLYKGLGATLLRDVPFS-VVYFPLFANLNQLG---------RPASEE------KSPFYVS-----FLAGCVA-------------GSAAAVAVNPCDVVKTRLQSLQRGV------NEDT-YS---------GILDCARK-ILRHE----GPS-AFLKGAYCRALVIAPLFGIAQVV---Y----------------------------------------------------------------------------------FLGIAESL---LGLLQDPQA------------- SLC25A23 ------------------MRGSPGDAERR--QRWGRLFE--------ELDSNKDGRV-----DVHELRQGLARLG---GGNPDPGAQQGISSEGDADPDGGLDLEE---FSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQ-----------------------------------SFRALGISISLEQAEK--ILHSMDRDGTMT-----------------------------------------------------------IDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTV-----PDE-------FSKQEKLTGMWWKQLVA-------------------------------------------------------G----------AVAGAVSR-TGTAPLDRLKVFMQVH---------------------------------------------------------ASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILG----QQETL--------HVQERFVAGSLAGAT-AQT---IIYPMEVLKTRLT-----------------------------------------LRRTGQY-KGLL------DCARRI-LERE--GP----------RAFYRGYLPNVLGIIPYA-GIDLAVYETLKNWWLQQ-YSH----------DSADPGILVL------LACGTIS-------------STCGQIASYPLALVRTRMQAQASIE-----GGPQLSML---------GLLRHILS----QE----GMR-GLYRGIAPNFMKVIPAVSISYVV---YE-----------------------------------NMKQAL-GVTSR------------------------------------------------------------------- SLC25A24 --------MLRWLRDFVLPTAACQDAEQP--TRYETLFQ--------ALDRNGDGVV-----DIGELQEGLRNLGIPLGQD----AEEKIFTTGDVNKDGKLDFEE---FMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQ-----------------------------------SLQTLGLTISEQQAEL--ILQSIDVDGTMT-----------------------------------------------------------VDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI-----PDE-------FTEDEKKSGQWWRQLLA-------------------------------------------------------G----------GIAGAVSR-TSTAPLDRLKIMMQVH---------------------------------------------------------GSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE----EGQKI--------GTFERFISGSMAGAT-AQT---FIYPMEVMKTRLA-----------------------------------------VGKTGQY-SGIY------DCAKKI-LKHE--GL----------GAFYKGYVPNLLGIIPYA-GIDLAVYELLKSYWLDN-FAK----------DSVNPGVMVL------LGCGALS-------------STCGQLASYPLALVRTRMQAQAMLE-----GSPQLNMV---------GLFRRIIS----KE----GIP-GLYRGITPNFMKVLPAVGISYVV---YE-----------------------------------NMKQTL-GVTQK------------------------------------------------------------------- SLC25A25 ------------MLCLCLYVPVIGEAQTE--FQY---FESKGLP--AELKSIFKLSVFIPSQEFSTYRQ----------------WKQKIVQAGDKDLDGQLDFEE---FVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQ-----------------------------------SLRDLGVKISEQQAEK--ILKSMDKNGTMT-----------------------------------------------------------IDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV-----PDE-------FTVEERQTGMWWRHLVA-------------------------------------------------------G----------GGAGAVSR-TCTAPLDRLKVLMQVH---------------------------------------------------------ASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS----DQETL--------RIHERLVAGSLAGAI-AQS---SIYPMEVLKTRMA-----------------------------------------LRKTGQY-SGML------DCARRI-LARE--GV----------AAFYKGYVPNMLGIIPYA-GIDLAVYETLKNAWLQH-YAV----------NSADPGVFVL------LACGTMS-------------STCGQLASYPLALVRTRMQAQASIE-----GAPEVTMS---------SLFKHILR----TE----GAF-GLYRGLAPNFMKVIPAVSISYVV---YE-----------------------------------NLKITL-GVQSR------------------------------------------------------------------- SLC25A26 -----------------------MDR---------------------------PGFVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALVA-------------------------------------------------------G----------GVAGVSVD-LILFPLDTIKTRLQSPQG-------------------------------------------------------FSKA---------------GGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFL----HADSSSY-------LTPMKHMLAASAGEVV-ACL---IRVPSEVVKQRAQ-------------V-------------------------------SAS-TRTF------QIFSNI-LYEE--GI----------QGLYRGYKSTVLREIPFS-LVQFPLWESLKALWSWR-------------------QDHVVDSW-QSAVCGAFA-------------GGFAAAVTTPLDVAKT------RITLA--KAGSSTADG---------NVLSVLHG-VWRSQ----GLA-GLFAGVFPRM------AAISLGG---FI-----------------------------------FLGAYDRTHSLLLEVGRKSP----------------------------------------------------------- SLC25A27 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPEEEERLLP--------------------------------------LTQRWPRASKFLL-------------------------------------------------------S----------GCAATVAE-LATFPLDLTKTRLQMQGEAAL---------------------------------------------ARLGDGARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDE----------HYPLWKSVIGGMMAGVI-GQF---LANPTDLVKVQMQ-------------MEGKRKL---------------------EGKPLRF-RGVH------HAFAKI-LAEG--GI----------RGLWAGWVPNIQRAALVN-MGDLTTYDTVKHYL----VLNTPL-----------EDNIMTH-----GLSSLCS-------------GLVASILGTPADVIKSRIMNQPRDK-----QGRGLLYK---------SSTDCLIQ-AVQGE----GFM-SLYKGFLPSWLRMTPWSMVFWLT---YE-----------------------------------KIREMSGVS-------------------------------------------------PF------------------- SLC25A28 -----------------------MELEGR-----------------------GAGGVA----------------------------------GGPAAGPGRSPGESA-LLDGWLQ-----------------------------------------------------------------------------------RGVGRGAGGGE--------------------------AGAC-----------------------RPPVRQDPDSGPDYEALPAGATV-----------------------------------------------TTHMVA-------------------------------------------------------G----------AVAGILEH-CVMYPIDCVKTRMQSLQP-------------------------------------------------------DPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNS-------------HIANGAAGCVA-TLLHDAAMNPAEVVKQRMQ-------------MY-----------------------------NSPY-HRVT------DCVRAV-WQNE--GA----------GAFYRSYTTQLTMNVPFQ-AIHFMTYEFLQEHFNPQ-RRY-------------NPSSHVLS--------GACA-------------GAVAAAATTPLDVCKTLLNTQESLALN---SHITGHIT---------GMASAFRT-VYQVG----GVT-AYFRGVQARVIYQIPSTAIAWSV---YE-----------------------------------FFKYLITKRQEEWRAGK-------------------------------------------------------------- SLC25A29 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALDFLA-------------------------------------------------------G----------CAGGVAGV-LVGHPFDTVKVRLQVQSV--------------------------------------------------------EKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS-------------P---LNQFLAGAAAGAI-QCV---ICCPMELAKTRLQ----L---------Q-------------------------DAGPARTY-KGSL------DCLAQI-YGHE--GL----------RGVNRGMVSTLLRETPSF-GVYFLTYDALTRALG-------CEPGDRL-------LVPKL------LLAGGTS-------------GIVSWLSTYPVDVVKSRLQADGLR-------GAPR-YR---------GILDCVHQ-SYRAE----GWR-VFTRGLASTLLRAFPVNAATFAT---VT-----------------------------------VVLTYARGEEAG--PEG-EAVPAAPA-------------------------------GPALAQPSSL------------ SLC25A3 ------------------MFSSVAHLARA--------------------------------NPFNTPHLQLVHDGLGDLRSSSPGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGQPRRPRNLAAAAVEEQYSC-----------DYG-------------------------------SGRFFI----------------------------------LCGLG----------------G----------IISCGTTH-TALVPLDLVKCRMQV-----------------------------------------------------------DPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTY-------LWRTSLYLAASASAEFF-ADI---ALAPMEAAKVRIQ--------------------------------T-----------QPGY-ANTL-----RDAAPKM-YKEE--GL----------KAFYKGVAPLWMRQIPYT-MMKFACFERTVEALYKF-----VVPKPRS--ECSKPEQLVVT-----FVAGYIA-------------GVFCAIVSHPADSVVSVLNKEKGSSASL----------------------------VLKRL----GFK-GVWKGLFARIIMIGTLTALQWFI---YD-----------------SVKVYFRLPRPPPPEMPESLKKKLGLTQ--------------------------------------------------------------------- SLC25A30 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAL-------------------------------------------NW---KPFVY-------------------------------------------------------G----------GLASITAE-CGTFPIDLTKTRLQIQGQTND---------------------------------------------AKF-----KEIRYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDE----------TLPI--NVICGILSGVI-SST---IANPTDVLKIRMQ-------------AQSN-TI---------------------QG-------GMI------GNFMNI-YQQE--GT----------RGLWKGVSLTAQRAAIVV-GVELPVYDITKKHL----ILSGLM-----------GDTVYTH-----FLSSFTC-------------GLAGALASNPVDVVRTRMMNQRVLR-----DGRCSGYT---------GTLDCLLQ-TWKNE----GFF-ALYKGFWPNWLRLGPWNIIFFVT---YE-----------------------------------QLKKLDL------------------------------------------------------------------------ SLC25A31 ------------------MHREPAKKKAE-----KRLFD----------------------------------------------------------------------------------ASSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKDLLA-------------------------------------------------------G----------GVAAAVSK-TAVAPIERVKLLLQVQAS---------------------------------------------------SKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMS--GVNKEKQ-----FWRWFLANLASGGAAGAT-SLC---VVYPLDFARTRLG-------------V-----------------------DIGKGPEERQF-KGLG------DCIMKI-AKSD--GI----------AGLYQGFGVSVQGIIVYR-ASYFGAYDTVKGL----------LP------KPKKTPFLVS------FFIAQVV-------------TTCSGILSYPFDTVRRRMMMQSGE-------A-KRQYK---------GTLDCFVK-IYQHE----GIS-SFFRGAFSNVLRGT-GGALVLVL---YD-----------------------------------KIKEFF-HIDIGGR----------------------------------------------------------------- SLC25A32 ------------------MTGQGQSASGS--SAWSTVFR----------------HV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R----------------------------------------------------------YENLIA-------------------------------------------------------G----------VSGGVLSN-LALHPLDLVKIRFAVSDGL------------------------------------------------------ELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEG---RAERL--------EATEYLVSAAEAGAM-TLC---ITNPLWVTKTRLM-------------LQY---------------------DAVVNSPHRQY-KGMF------DTLVKI-YKYE--GV----------RGLYKGFVPGLFGT-SHG-ALQFMAYELLKLKYNQH-INR--LP------EAQLSTV-------EYISVAALS-------------KIFAVAATYPYQVVRARLQDQ------------HMFYS---------GVIDVITK-TWRKE----GVG-GFYKGIAPNLIRVTPACCITFVV---YE-----------------------------------NVSHFLLDLREKRK----------------------------------------------------------------- SLC25A33 ------------------MATGGQQKENT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLHLFA-------------------------------------------------------G----------GCGGTVGA-IFTCPLEVIKTRLQSSRLAL-RTVYYPQVHL---------------------------------GTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIV------------HIFSAGSAAFI-TNS---LMNPIWMVKTRMQ-------------L-----------------------EQ-KVRGSKQM--NTL------QCARYV-YQTE--GI----------RGFYRGLTASYAGI-SET-IICFAIYESLKKYLKEA-PLA-SSANGTE----KNSTSFFGL-----MAAAALS-------------KGCASCIAYPHEVIRTRLREEGTK---------YKSFV---------QTARLVFR----EE----GYL-AFYRGLFAQLIRQIPNTAIVLST---YE-----------------------------------LIVYLLEDRTQ-------------------------------------------------------------------- SLC25A34 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METVPPAVDLVL-------------------------------------------------------G----------ASACCLAC-VFTNPLEVVKTRLQLQGELQ----------------------------------------------ARGT----YPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGL----------------TQQPGGTVVAGAVAGAL-GAF---VGSPAYLIKTQLQ-------------AQTVAAV--------------------AVGHQHNH-QTVL------GALETI-WRQQ--GL----------LGLWQGVGGAVPRVMVGS-AAQLATFASAKAWV----QKQQWLP----------EDSWLVA-----LAGGMIS-------------SIAVVVVMTPFDVVSTRLYNQPVDT-----AGRGQLYG---------GLTDCMVK-IWRQE----GPL-ALYKGLGPAYLRLGPHTILSMLF---WD-----------------------------------ELRKLAGRAQHK--------------------------------------------------GT--------------- SLC25A35 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFLM-------------------------------------------------------S----------GLAACGAC-VFTNPLEVVKTRMQLQGELQ----------------------------------------------APGT----YQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEG----------THSPARSAAAGAMAGVM-GAY---LGSPIYMVKTHLQ-------------AQAASEI--------------------AVGHQYKH-QGMF------QALTEI-GQKH--GL----------VGLWRGALGGLPRVIVGS-STQLCTFSSTKDLL----SQWEIFP----------PQSWKLA-----LVAAMMS-------------GIAVVLAMAPFDVACTRLYNQPTDA-----QGKNRVPKF--------SATSC------SAS----APL-LGTK-----------------------------------------------------------DVRIVKGQTGHQLFKVTQAP-----------------------------------GCSPILLGTQS------------- SLC25A36 -----------------------MSQRDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVHLFA-------------------------------------------------------G----------GCGGTVGA-ILTCPLEVVKTRLQSSSV----TLYISEVQL---------------------------------NTMAGASVNR--VVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV------------HMISAAMAGFT-AIT---ATNPIWLIKTRLQ-------------L-----------------------DA-RNRGERRM--GAF------ECVRKV-YQTD--GL----------KGFYRGMSASYAGI-SET-VIHFVIYESIKQKLLEY-KTA-STMENDEE-SVKEASDFVGM-----MLAAATS-------------KTCATTIAYPHEVVRTRLREEGTK---------YRSFF---------QTLSLLVQ----EE----GYG-SLYRGLTTHLVRQIPNTAIMMAT---YE-----------------------------------LVVYLLNG----------------------------------------------------------------------- SLC25A37 -----------------------MELR--------------------------SGSV------------------------------------GSQAVARRMDGDS------------------------------------------------------------------------------------------------RDGGGG-----------------------------------------------------------KDATGSEDYENLPTSASV-----------------------------------------------STHMTA-------------------------------------------------------G----------AMAGILEH-SVMYPVDSVKTRMQSLSP-------------------------------------------------------DPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNS-------------HLANGIAGSMA-TLLHDAVMNPAEVVKQRLQ-------------MY-----------------------------NSQH-RSAI------SCIRTV-WRTE--GL----------GAFYRSYTTQLTMNIPFQ-SIHFITYEFLQEQVNPH-RTY-------------NPQSHIIS--------GGLA-------------GALAAAATTPLDVCKTLLNTQENVALS--LANISGRLS---------GMANAFRT-VYQLN----GLA-GYFKGIQARVIYQMPSTAISWSV---YE-----------------------------------FFKYFLTKRQLENRAPY-------------------------------------------------------------- SLC25A38 --------------------------------------------------------MI---------------------QNSRPSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQPQ----------DVGDTV---------------------ETLMLHPVIKAFL------------------------------------------------------CG----------SISGTCST-LLFQPLDLLKTRLQTLQPSD------------------------------------------------------HGSRRVGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGH-------------PPTALESVMLGVGSRSV-AGV---CMSPITVIKTRYE-------------------------SG-------------KYGYESIY-----------AALRSI-YHSE--GH----------RGLFSGLTATLLRDAPFS-GIYLMFYNQTKNIVPHDQVDATLIP--------------ITN-----FSCGIFA-------------GILASLVTQPADVIKTHMQLYPLK------------FQ---------WIGQAVTL-IFKDY----GLR-GFFQGGIPRALRRTLMAAMAWTV---YE-----------------------------------EMMAKMGLKS--------------------------------------------------------------------- SLC25A39 --------------------------------------------------------M----------------------ADQDPA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GISPLQQMVA-------------------------------------------------------S----------GTGAVVTS-LFMTPLDVVKVRLQSQRPSMASEL-MPSSRLWSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL------------TSDLYAPMVAGALARLG-TVT---VISPLELMRTKLQ-------------AQHVSYRELG------------------------------------ACVRTA-VAQG--GW----------RSLWLGWGPTALRDVPFS-ALYWFNYELVKSWL-----NG-FRPKD--------QTSVGMS-----FVAGGIS-------------GTVAAVLTLPFDVVKTQRQVALGAM------EAVR-VN--P--LHVDSTWLLLRR-IRAES----GTK-GLFAGFLPRIIKAAPSCAIMIST---YE-----------------------------------FGKSFFQRLNQDRLLGG-------------------------------------------------------------- SLC25A4 ------------------------------------MGD---------------------------------------------------------------------------------HAWSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKDFLA-------------------------------------------------------G----------GVAAAVSK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLG--GVDRHKQ-----FWRYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKGAAQREF-HGLG------DCIIKI-FKSD--GL----------RGLYQGFNVSVQGIIIYR-AAYFGVYDTAKGM----------LP------DPKNVHIFVS------WMIAQSV-------------TAVAGLVSYPFDTVRRRMMMQSGRK-----GA-DIMYT---------GTVDCWRK-IAKDE----GAK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------EIKKYV------------------------------------------------------------------------- SLC25A40 ---------------------------------------------------------------------------------MDPET---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGQ-----------------------EIIKVTPLQQMLA-------------------------------------------------------S----------CTGAILTS-VIVTPLDVVKIRLQAQN-------------------NPLPK-----GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLG------------ENETCIPIVAGIVARFG-AVT---VISPLELIRTKMQ-------------SKKFSYVELH------------------------------------RFVSKK-VSED--GW----------ISLWRGWAPTVLRDVPFS-AMYWYNYEILKKWLC--EKSGLYEP------------TFMIN-----FTSGALS-------------GSFAAVATLPFDVVKTQKQTQLWTY------ESHK-ISM-P--LHM-STWIIMKN-IVAKN----GFS-GLFSGLIPRLIKIAPACAIMIST---YE-----------------------------------FGKAFFQKQNVRRQQY--------------------------------------------------------------- SLC25A41 ------------------MGAQPGEPQNTC-SRIQTLFR----------------RV--------------KTLLIKAPPPPQPPPPPPSWNPGCTHVYG----------------------YAFGHMHDNNLEHLPSQQV------------------------------------------------------------------------------------------------------------------------------------------------------------LDTGEQLMV-----PVE-------VLEVDNKEAL-WKFLLS-------------------------------------------------------G----------AMAGAVSR-TGTAPLDRAKVYMQVY---------------------------------------------------------SSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG----IQGSP--------PFQERLLAGSLAVAI-SQT---LINPMEVLKTRLT-----------------------------------------LRRTGQY-KGLL------DCARQI-LQRE--GT----------RALYRGYLPNMLGIIPYA-CTDLAVYEMLQCFWVKS--GR----------DMGDPSGLVS------LSSVTLS-------------TTCGQMASYPLTLVRTRMQAQDTVE-----GS-NPTMR---------GVLQRILA----QQ----GWL-GLYRGMTPTLLKVLPAGGISYVV---YE-----------------------------------AMKKTL-GI---------------------------------------------------------------------- SLC25A42 ------------------MGNGVKEGPVR-------------------------------------------------LHED----AEAVLSSSVSSK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDHRQV-----------------------------------------------------LSSLLS-------------------------------------------------------G----------ALAGALAK-TAVAPLDRTKIIFQVS---------------------------------------------------------SKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEAL--------PPWPRLFAGALAGTT-AAS---LTYPLDLVRARMA-----------------------------------------VTPKEMY-SNIF------HVFIRI-SREE--GL----------KTLYHGFMPTVLGVIPYA-GLSFFTYETLKSLHREY-SGR-RQPYPFER-----------------MIFGACA-------------GLIGQSASYPLDVVRRRMQT-AGVT-----GYPRASIA---------RTLRTIVR----EE----GAVRGLYKGLSMNWVKGPIAVGISFTT---FD-----------------------------------LMQILLRHLQS-------------------------------------------------------------------- SLC25A43 ------------------MATWRRDGRLT------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRLLC-------------------------------------------------------A----------GLAGTLSL-SLTAPLELATVLAQVG---------------------------------------------------------VVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLG------------HISQWSSIMAGSLAGMV-STI---VTYPTDLIKTRLI-------------M--------------------------QNILEPSY-RGLL------HAFSTI-YQQE--GF----------LALYRGVSLTVVGALPFS-AGSLLVYMNLEKIWNGP-RDQFSLP--------------------QNFANVCLA-------------AAVTQTLSFPFETVKRKMQAQSPYLPH--SGGVDVHFS---------GAVDCFRQ-IVKAQ----GVL-GLWNGLTANLLKIVPYFGIMFST---FEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL------------------------------------------------------------- SLC25A44 -----------------------MEDKRNI-------------------------------------------------------------------------------------------------------------QIIE----------------------------------------------------------------------------------------------------------------------------------------------------WEH---LD---------------------------------KKKFYV----------------------------------------------------F--G----------VAMTMMIR-VSVYPFTLIRTRLQVQ---------------------------------------------------------KGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLI-SGQCYVTTYELTRKFVADYS-------------QSNTVKSLVAGGSASLV-AQS---ITVPIDVVSQHLM-------------MQRKGEKMGRF----------------QVRGNPEG-QGVVAFGQTKDIIRQI-LQAD--GL----------RGFYRGYVASLLTYIPNS-AVWWPFYHFYAEQLSYL--------------CPKECPHIVFQ-----AVSGPLA-------------AATASILTNPMDVIRTRVQVEGKN-----------------------SIILTFRQ-LMAEE----GPW-GLMKGLSARIISATPSTIVIVVG---YE-----------------------------------SLKKLSLRPELVDSRHW-------------------------------------------------------------- SLC25A45 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVEEFVA-------------------------------------------------------G----------WISGALGL-VLGHPFDTVKVRLQTQ------------------------------------------------------------TTYRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQ-----PP-SYMHIFLAGCTGGFL-QAY---CLAPFDLIKVRLQ----N---------QTEPRAQ-------------------PGSPPPRY-QGPV------HCAASI-FREE--GP----------RGLFRGAWALTLRDTPTV-GIYFITYEGLCRQY---------TPEGQN------PSSATV------LVAGGFA-------------GIASWVAATPLDMIKSRMQMDGL--------RRRV-YQ---------GMLDCMVS-SIRQE----GLG-VFFRGVTINSARAFPVNAVTFLS---YE-----------------------------------YLLRWWG------------------------------------------------------------------------ SLC25A46 -----------------------MHPRRPD------GFDGLG-YRGGARDEQGFGGAFPA-RSFSTGSD------LGHWVTTPPDIP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSRNLH--------------WGEKS-PPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAG----------------------------------------------------F--G---------IGLASLFTENVLAHPCIVLRRQCQVNYHAQHYHL------------TPF-----------------------------------------TVINIMYSFNKTQGPRALWKGMGSTFI----VQGVTLGAEGIISEFTPLPREVLHKWS------PKQIGEHLLLKSLTYVV-AMP-FYSASLIETVQSEII--------RDN--------------------------------------TGIL--ECVKEGIGRV------IGM-GVPHSKRL-LPLLSLIFPTVLHG-----VLHYIISSVIQKFVLLI-LKRKTYNSHLA--ESTSPVQSMLDAYFPELIANFAA-------------SLCSDVILYPLETVLHRLHIQGTRT---IIDNTDLGYEVLPINTQYEGMRDCINT-IRQEE----GVF-GFYKGFGAVIIQYTLHAAVLQITKIIYS--------------T--------------------LLQNNI------------------------------------------------------------------------- SLC25A47 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFVA-------------------------------------------------------G----------AIGGVCGV-AVGYPLDTVKVRIQTE------------------------------------------------------------PKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK------P-TKADITLSGCASGLV-RVF---LTSPTEVAKVRLQ----T---------QTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKY-RGPL------HCLATV-AREE--GL----------CGLYKGSSALVLRDGHSF-ATYFLSYAVLCEWL---------SPAGHSR-----PDVPGV------LVAGGCA-------------GVLAWAVATPMDVIKSRLQADGQ--------GQRR-YR---------GLLHCMVT-SVREE----GPR-VLFKGLVLNCCRAFPVNMVVFVA---YE-----------------------------------AVLRLARGLLT-------------------------------------------------------------------- SLC25A48 -------------------------------------------------------------------------------MG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SFQLEDFAA-------------------------------------------------------G----------WIGGAASV-IVGHPLDTVKTRLQAG------------------------------------------------------------VGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEAS-----PPRTLSDLLLASMVAGVV-SVG---LGGPVDLIKIRLQ----M---------QTQPFRD-----------------------------GGE------HRMTTV-F------------------------------------------------------------PGPHL-----------------------------------------------------------------------------------------CM-------------------------------------------------------------------------------------------------------------------------------------------------------------- SLC25A49 MGASDPEVAPWARGGAAGMAGAGAGAGARG-----------G----------AAAGVEAR------------------ARDPPPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRA-----------------------------HPRHPRPAAQPSA----------------------------RRMDGGSGGLGS---------------GDNAPTTEALFVALGAGVT-ALSHPLLYVKLLIQVGHEPMPPTL----------------------GTNVLG---------------------RKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLM----SNALSTVTRGSMKKVF-PPDEIEQVSN---KDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCM-------------VQ-------------------------FVGREAKY-SGVL------SSIGKI-FKEE--GL----------LGFFVGLIPHLLGD-----VVFLWGCNLLAHFINAY------------------------------LVDDSFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGL-----QAGLPPYS--P---VFKSWIHCWK--YLSVQ----G---QLFRGSSLLFRRVSSGSCFAL------------------------------------------E------------------------------------------------------------------------------ SLC25A5 ------------------------------------MTD---------------------------------------------------------------------------------AAVSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKDFLA-------------------------------------------------------G----------GVAAAISK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQ-----FWLYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKAGAEREF-RGLG------DCLVKI-YKSD--GI----------KGLYQGFNVSVQGIIIYR-AAYFGIYDTAKGM----------LP------DPKNTHIVIS------WMIAQTV-------------TAVAGLTSYPFDTVRRRMMMQSGRK-----GT-DIMYT---------GTLDCWRK-IARDE----GGK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------EIKKYT------------------------------------------------------------------------- SLC25A50 ------------------MADA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASQ---------------------------------------------------------------------VLLGSGLT-ILSQPLMYVKVLIQVGYEPLPPTI----------------------GRNIFG---------------------RQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLC----SGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSM-------------VQ-------------------------FIGRESKY-CGLC------DSIITI-YREE--GI----------LGFFAGLVPRLLGD-----ILSLWLCNSLAYLVNTY------------------------------ALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGL-----AGGCPPYS--P---IYTSWIDCWC--MLQKE----G---NMSRGNSLFFRKVPFGKTYCC------------------------------------------DLKMLI------------------------------------------------------------------------- SLC25A51 ------------------MMDSEAHEKRPP-------------------------------------------ILTSSKQDISPHI----------------------------------------------------TNVGE----------------------------------------------------------------------------------------------------------------------------------------------------MKH-----------------------------------------YLC-------------------------------------------------------G----------CCAAFNNV-AITFPIQKVLFRQQLYGIKTRDAI------------------LQ---------------------------------------------LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLH------KHVS------APEFATSGVAAVLAGTT-EAI----FTPLERVQTLLQ----------------------------------------DHKHHDKF-TNTY------QAFKAL--KCH--GI-G-----E----YYRGLVPILFRNGLSN-VLFFGLRGPIKEHLP----------------TATTHSAHLVND----FICGGLL-------------GAMLGFLFFPINVVKTRIQSQIGGE-----------FQ------SFPKVF---QK-IWLERDR--KLI-NLFRGAHLNYHRSLISWGIINAT---YEFL----------------------------------LKVI-------------------------------------------------------------------------- SLC25A52 --------MPFMRKILSNMIDSEAHEKRPP-------------------------------------------ILTSSKQDISPHI----------------------------------------------------TNVGE----------------------------------------------------------------------------------------------------------------------------------------------------MKH-----------------------------------------YLC-------------------------------------------------------G----------CCAAFNNV-AITYPIQKVLFRQQLYGIKTRDAV------------------LQ---------------------------------------------LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLR------KHVR------APEFATHGVAAVLAGTA-EAI----FTPLERVQTLLQ----------------------------------------NHKHHDKF-TNTY------QAFKAL--KCH--GI-G-----E----YYRGLVPILFRNGLSN-VLFFGLRGPIKEHLP----------------TATTHSAHLVND----FIGGGLL-------------GAMLGFLCFPINVVKTRLQSQIGGE-----------FQ------SFPKVF---QK-IWLERDR--KLI-NLFRGAHLNYHRSLISWGIINAT---YEFL----------------------------------LKFI-------------------------------------------------------------------------- SLC25A53 ----------------------------------------------------------------------------MGEQNHSPG--------------------------------------------------------KE----------------------------------------------------------------------------------------------------------------------------------------------------LQHRT-------------------------RAEAPGKKSWHSQAYAL-------------------------------------------------------G----------AVSNFMST-FLTFPIYKVVFRQQIHAMAVSEAV------------------RQ---------------------------------------------LWHEGPQYFYRGIYPPLLSKTLQGTLLFGTYDSLLCFLSPV---GPHTL------GHRWA----AGLMSGVV-EAV---ALSPFERVQNVLQ----------------------------------------DGRKQARF-PSTF------SILKEF--NSY--GLWG-----RLSLGYYRGFWPVLARNSLGS-ALYFSFKDPIQDGL------------------AEQGLPHWVPA----LVSGSVN-------------GTITCLVLYPLIVLVANMQSHIG-------------WQ------NMPSLWASAQD-VWNTRGR--KLL-LIYRGGSLVILRSSVTWGLTTAI---HDFLQRKSH----------SRK---------------ELKTD-------------------------------------------------------------------------- SLC25A6 ------------------------------------MTE---------------------------------------------------------------------------------QAISF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKDFLA-------------------------------------------------------G----------GIAAAISK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKHTQ-----FWRYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKSGTEREF-RGLG------DCLVKI-TKSD--GI----------RGLYQGFSVSVQGIIIYR-AAYFGVYDTAKGM----------LP------DPKNTHIVVS------WMIAQTV-------------TAVAGVVSYPFDTVRRRMMMQSGRK-----GA-DIMYT---------GTVDCWRK-IFRDE----GGK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------ELKKVI------------------------------------------------------------------------- SLC25A7 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGLTA--------------------------------------SDVHPTLGVQLFS-------------------------------------------------------A----------GIAACLAD-VITFPLDTAKVRLQVQGE------------------------------------------------CPTS----SVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLT-AGKET----------APSLGSKILAGLTTGGV-AVF---IGQPTEVVKVRLQ-------------AQSHLH-----------------------GIKPRY-TGTY------NAYRII-ATTE--GL----------TGLWKGTTPNLMRSVIIN-CTELVTYDLMKEAF----VKNNIL-----------ADDVPCH-----LVSALIA-------------GFCATAMSSPVDVVKTRFINSPPGQ-----------YK---------SVPNCAMK-VFTNE----GPT-AFFKGLVPSFLRLGSWNVIMFVC---FE-----------------------------------QLKRELSKSRQTMD-------------------------------------------CAT------------------- SLC25A8 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGFKA--------------------------------------TDVPPTATVKFLG-------------------------------------------------------A----------GTAACIAD-LITFPLDTAKVRLQIQGESQG--------------------------------------------PVRAT----ASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEH----------A-SIGSRLLAGSTTGAL-AVA---VAQPTDVVKVRFQ-------------AQARAG------------------------GGRRY-QSTV------NAYKTI-AREE--GF----------RGLWKGTSPNVARNAIVN-CAELVTYDLIKDAL----LKANLM-----------TDDLPCH-----FTSAFGA-------------GFCTTVIASPVDVVKTRYMNSALGQ-----------YS---------SAGHCALT-MLQKE----GPR-AFYKGFMPSFLRLGSWNVVMFVT---YE-----------------------------------QLKRALMAACTSRE-------------------------------------------APF------------------- SLC25A9 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGLKP--------------------------------------SDVPPTMAVKFLG-------------------------------------------------------A----------GTAACFAD-LVTFPLDTAKVRLQIQGENQA---------------------------------------------VQTA----RLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADN----------S-SLTTRILAGCTTGAM-AVT---CAQPTDVVKVRFQ-------------ASIHLGP---------------------SRSDRKY-SGTM------DAYRTI-AREE--GV----------RGLWKGTLPNIMRNAIVN-CAEVVTYDILKEKL----LDYHLL-----------TDNFPCH-----FVSAFGA-------------GFCATVVASPVDVVKTRYMNSPPGQ-----------YF---------SPLDCMIK-MVAQE----GPT-AFYKGFTPSFLRLGSWNVVMFVT---YE-----------------------------------QLKRALMKVQMLRE-------------------------------------------SPF-------------------
Variant
check | gene name | residue number | Reference Amino Acid / Variant Amino Acid | minor allele frequency | rs number |
---|---|---|---|---|---|
-- | SLC25A45 | 3 | V/A | 0.000272466 | rs776192965 |
-- | SLC25A45 | 19 | L/P | 0.000136318 | rs778534097 |
-- | SLC25A45 | 37 | R/Q | 0.000196456 | rs202169779 |
-- | SLC25A45 | 37 | R/W | 0.00011226 | rs377005228 |
-- | SLC25A45 | 40 | V/I | 0.000629415 | rs74531249 |
-- | SLC25A45 | 58 | G/E | 0.00335384 | rs78829599 |
-- | SLC25A45 | 74 | F/S | 0.00039306 | rs553288642 |
-- | SLC25A45 | 89 | H/Y | 0.000136395 | rs745954311 |
-- | SLC25A45 | 100 | M/T | 0.00824699 | rs79141870 |
-- | SLC25A45 | 103 | F/L | 0.000706654 | rs537612152 |
-- | SLC25A45 | 135 | A/T | 0.000145068 | rs375786817 |
-- | SLC25A45 | 141 | P/Q | 0.000209962 | rs200825852 |
-- | SLC25A45 | 149 | H/R | 0.000198156 | rs199936582 |
-- | SLC25A45 | 160 | P/L | 0.000169635 | rs200903144 |
-- | SLC25A45 | 161 | R/W | 0.000957529 | rs34377244 |
-- | SLC25A45 | 171 | T/M | 0.000116535 | rs368023459 |
-- | SLC25A45 | 174 | D/V | 0.000128526 | rs182802664 |
-- | SLC25A45 | 190 | R/H | 0.00128783 | rs200629305 |
-- | SLC25A45 | 224 | M/V | 0.993836 | rs624307 |
-- | SLC25A45 | 233 | G/R | 0.0010552 | rs145807288 |
-- | SLC25A45 | 236 | R/H | 0.000116391 | rs143413687 |
-- | SLC25A45 | 251 | R/Q | 0.00354207 | rs7108281 |
-- | SLC25A45 | 285 | R/H | 0.00212135 | rs147014725 |
-- | SLC25A45 | 285 | R/C | 0.0260189 | rs34400381 |
Phylogenetic tree
Pathway
Priority | Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|---|
No data |
Disease
Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|
No data |