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Basic
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Seq./Align.
Variant
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Disease

Detail Data SLC25A25


Basic description
Gene Name SLC25A25
Protein Name Calcium-binding mitochondrial carrier protein SCaMC-2 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)
Family SLC25
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460 
MLCLCLYVPV IGEAQTEFQY FESKGLPAEL KSIFKLSVFI PSQEFSTYRQ WKQKIVQAGD KDLDGQLDFE EFVHYLQDHE KKLRLVFKSL DKKNDGRIDA QEIMQSLRDL GVKISEQQAE KILKSMDKNG TMTIDWNEWR DYHLLHPVEN IPEIILYWKH STIFDVGENL TVPDEFTVEE RQTGMWWRHL VAGGGAGAVS RTCTAPLDRL KVLMQVHASR SNNMGIVGGF TQMIREGGAR SLWRGNGINV LKIAPESAIK FMAYEQIKRL VGSDQETLRI HERLVAGSLA GAIAQSSIYP MEVLKTRMAL RKTGQYSGML DCARRILARE GVAAFYKGYV PNMLGIIPYA GIDLAVYETL KNAWLQHYAV NSADPGVFVL LACGTMSSTC GQLASYPLAL VRTRMQAQAS IEGAPEVTMS SLFKHILRTE GAFGLYRGLA PNFMKVIPAV SISYVVYENL KITLGVQSR 
CCEEEEEEEC CCHHHHHHHH HHHCCCCCCC CCHHHHHHHH HHCCCCHHHH HHHHHHHHHC CCCCCCCCHH HHHHHHHHHH HHHHHHHHHH CCCCCCCCCH HHHHHHHHHC CCCCCHHHHH HHHHHCCCCC CCCCCHHHHH HHHHCCCCCC CCHHHHHCCC CCEEEECCCE ECCCCCCCCC CCCCCHHHHH HHHHHHHHHH HHHHCCHHHH HHHHHHCCCC CCCCCHHHHH HHHHHHCCHH HHHCCHHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCCCH HHHHHHHHHH HHHHHHHHCC HHHHHHHHHC CCCCCCCCHH HHHHHHHHHH CHHHHCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCCCCCHH HHHHHHHHHH CHHHHHCCHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCC
[Overview] SLC25A1 SLC25A10 SLC25A11 SLC25A12 SLC25A13 SLC25A14 SLC25A15 SLC25A16 SLC25A17 SLC25A18 SLC25A19 SLC25A2 SLC25A20 SLC25A21 SLC25A22 SLC25A23 SLC25A24 SLC25A25 SLC25A26 SLC25A27 SLC25A28 SLC25A29 SLC25A3 SLC25A30 SLC25A31 SLC25A32 SLC25A33 SLC25A34 SLC25A35 SLC25A36 SLC25A37 SLC25A38 SLC25A39 SLC25A4 SLC25A40 SLC25A41 SLC25A42 SLC25A43 SLC25A44 SLC25A45 SLC25A46 SLC25A47 SLC25A48 SLC25A49 SLC25A5 SLC25A50 SLC25A51 SLC25A52 SLC25A53 SLC25A6 SLC25A7 SLC25A8 SLC25A9 
SLC25A1   ----------------------------------------------------------------------------------MPAP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RAPRALAAAAPASG-----------------------------------------KAKLTHPGKAILA-------------------------------------------------------G----------GLAGGIEI-CITFPTEYVKTQLQLDERS-------------------------------------------------------HPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQG------------RLDSTRGLLCGLGAGVAEAVV---VVCPMETIKVKFI--------HD------------------------------QTSPNPKY-RGFF------HGVREI-VREQ--GL----------KGTYQGLTATVLKQGSNQ-AIRFFVMTSLRNWYRGD------NPNK--------PMNPLIT-----GVFGAIA-------------GAASVFGNTPLDVIKTRMQGLEAHK-----------YR---------NTWDCGLQ-ILKKE----GLK-AFYKGTVPRLGRVCLDVAIVFVI---YD-----------------------------------EVVKLLNKVWKTD------------------------------------------------------------------
SLC25A10  ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAEA-----------------------------------------------------RVSRWYF-------------------------------------------------------G----------GLASCGAA-CCTHPLDLLKVHLQTQQE------------------------------------------------VKLR-----------MTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVA-KGSQG----------PLPFHEKVLLGSVSGLA-GGF---VGTPADLVNVRMQ-------------NDVKLP----------------------QGQRRNY-AHAL------DGLYRV-AREE--GL----------RRLFSGATMASSRGALVT-VGQLSCYDQAKQLV----LSTGYL-----------SDNIFTH-----FVASFIAAAGD----EPPPQGGCATFLCQPLDVLKTRLMNSK---------GE---YQ---------GVFHCAVE-TAKL-----GPL-AFYKGLVPAGIRLIPHTVLTFVF---LE-----------------------------------QLRKNFGIKVPS-------------------------------------------------------------------
SLC25A11  ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATASAGAGGIDG--------------------------------------KPRTSPKSVKFLF-------------------------------------------------------G----------GLAGMGAT-VFVQPLDLVKNRMQLSGEGA------------------------------------------------------KTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLT-GADGT----------PPGFLLKAVIGMTAGAT-GAF---VGTPAEVALIRMT-------------ADGRLP----------------------ADQRRGY-KNVF------NALIRI-TREE--GV----------LTLWRGCIPTMARAVVVN-AAQLASYSQSKQFL----LDSGYF-----------SDNILCH-----FCASMIS-------------GLVTTAASMPVDIAKTRIQNMRMID------GKPE-YK---------NGLDVLFK-VVRYE----GFF-SLWKGFTPYYARLGPHTVLTFIF---LE-----------------------------------QMNKAYKRLFLSG------------------------------------------------------------------
SLC25A12  ------------------MAVKVQTTKRGDPHELRNIFLQ---Y--ASTEVDGERYMTP--EDFVQ-----RYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAI----------RYGQVTP-------------------LEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQ--SPGLGRPIWLQIAESAYRFTLG----------SVAGAVGA-TAVYPIDLVKTRMQNQRGSGS---------------------------------------------------VVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDG------------SVPLPAEVLAGGCAGGS-QVI---FTNPLEIVKIRLQVAGEI-----------------------------------TTGP-----RVSA-----LNVLRDL-------GI----------FGLYKGAKACFLRDIPFS-AIYFPVYAHCKLLL---------ADENGH------VGGLNL------LAAGAMA-------------GVPAASLVTPADVIKTRLQVAARA-------GQTT-YS---------GVIDCFRK-ILREE----GPS-AFWKGTAARVFRSSPQFGVTLVT---YE-----------------------------------LLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ
SLC25A13  -----------------MAAAKVALTKRADPAELRTIFLK---Y--ASIEKNGEFFMSP--NDFVT-----RYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQ----------KFGQVTP-------------------MEVDILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLG----------SVAGAVGA-TAVYPIDLVKTRMQNQRSTGS---------------------------------------------------FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG------------SVPLAAEILAGGCAGGS-QVI---FTNPLEIVKIRLQVAGEI-----------------------------------TTGP-----RVSA-----LSVVRDL-------GF----------FGIYKGAKACFLRDIPFS-AIYFPCYAHVKASF---------ANEDGQ------VSPGSL------LLAGAIA-------------GMPAASLVTPADVIKTRLQVAARA-------GQTT-YS---------GVIDCFRK-ILREE----GPK-ALWKGAGARVFRSSPQFGVTLLT---YE-----------------------------------LLQRWFYIDFGGVKPMGSEPVPKSRI-NLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFK-PSVSTSK---AIGGGP
SLC25A14  -------------------------------------------------------------------------------MGIFPGIILI------------------------------------------------------------------------FLRVKF-----------------------------------------------------------------ATAA------------------------------VIVSGHQKSTTVSHEMSGL-------------------------------------------NW---KPFVY-------------------------------------------------------G----------GLASIVAE-FGTFPVDLTKTRLQVQGQSID---------------------------------------------ARF-----KEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDE----------TLLI--NMICGVVSGVI-SST---IANPTDVLKIRMQ-------------AQGS-LF---------------------QG-------SMI------GSFIDI-YQQE--GT----------RGLWRGVVPTAQRAAIVV-GVELPVYDITKKHL----ILSGMM-----------GDTILTH-----FVSSFTC-------------GLAGALASNPVDVVRTRMMNQRAIV------GHVDLYK---------GTVDGILK-MWKHE----GFF-ALYKGFWPNWLRLGPWNIIFFIT---YE-----------------------------------QLKRLQI------------------------------------------------------------------------
SLC25A15  -------------------------------------------------------------------------------MKSNPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQAAIDLTA-------------------------------------------------------G----------AAGGTACV-LTGQPFDTMKVKMQT-----------------------------------------------------------FPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAK------L-SDLQNAAAGSFASAF-AAL---VLCPTELVKCRLQTMYEM---------E-------------------------TSGKIAKS-QNTV-----WSVIKSI-LRKD--GP----------LGFYHGLSSTLLREVPGY-FFFFGGYELSRSFF---------A-SGRSK---DELGPVPL------MLSGGVG-------------GICLWLAVYPVDCIKSRIQVLSMS-------GKQ---A---------GFIRTFIN-VVKNE----GIT-ALYSGLKPTMIRAFPANGALFLA---YE-----------------------------------YSRKLM---------------------------------------------------MNQLEAY---------------
SLC25A16  ------------------MAAATAAAALA-------------------------------------------------AADPPPAMPQAAGAGGPTTR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDFYW------------------------------------------------------LRSFLA-------------------------------------------------------G----------GIAGCCAK-TTVAPLDRVKVLLQAH---------------------------------------------------------NHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHV------------HRLMAGSMAGMT-AVI---CTYPLDMVRVRLA-------------F--------------------------QVKGEHSY-TGII------HAFKTIYAKEG--GF----------FGFYRGLMPTILGMAPYA-GVSFFTFGTLKSVGLSH-A-----PTLLGRPSSDNPNVLVLKTH-VNLLCGGVA-------------GAIAQTISYPFDVTRRRMQL-GTV-------LPEFEKC---------LTMRDTMKYVYGHH----GIRKGLYRGLSLNYIRCIPSQAVAFTT---YE-----------------------------------LMKQFF-HLN---------------------------------------------------------------------
SLC25A17  -------------------------------------------------------------------------------MAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLSYESLVHAVA-------------------------------------------------------G----------AVGSVTAM-TVFFPLDTARLRLQVDEKRK------------------------------------------------------SKTTHMVLLE----IIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQ-------------HSTTGKDLVVGFVAGVV-NVL---LTTPLWVVNTRLK-------------LQGAKFRN-------------------EDIVPTNY-KGII------DAFHQI-IRDE--GI----------SALWNGTFPSLLL--VFNPAIQFMFYEGLKRQL----LKKRMKLSSLDV-----------------FIIGAVA-------------KAIATTVTYPLQTVQSILRFGRHRL-----NPENR-TL---------GSLRNILY-LLHQRVRRFGIM-GLYKGLEAKLLQTVLTAALMFLV---YE-----------------------------------KLTA--------------------------------------ATFTVMGLKRAHQH-----------------------
SLC25A18  ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHQDLSIT------------------------------------------------------AKLIN-------------------------------------------------------G----------GVAGLVGV-TCVFPIDLAKTRLQN-QH--------------------------------------------------------GKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGM------------QRNLKMEMLAGCGAGMC-QVV---VTCPMEMLKIQLQDAGRLAVHH-----QGSASAP----STSRSY---------TTGSASTHRRPSA-----TLIAWEL-LRTQ--GL----------AGLYRGLGATLLRDIPFS-IIYFPLFANLNNLG---------FNELAG------KASFAHS-----FVSGCVA-------------GSIAAVAVTPLDVLKTRIQTLKKGL------GEDM-YS---------GITDCARK-LWIQE----GPS-AFMKGAGCRALVIAPLFGIAQGV---Y----------------------------------------------------------------------------------FIGIGERI---LKCFD-----------------
SLC25A19  -------------------------------------------------------MV---------------------GYDPKP-----------------------------------------------------------------------------------------------------------------------DG--------------------------------------------------------------------RNNTK------------------------------------------------------FQVAVA-------------------------------------------------------G----------SVSGLVTR-ALISPFDVIKIRFQLQHERLSRS--------------------------------------------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVH-----RGSVY-----DAREFSVHFVCGGLAACM-ATL---TVHPVDVLRTRFA-------------A---------------------------QGEPKVY-NTLR------HAVGTM-YRSE--GP----------QVFYKGLAPTLIAIFPYA-GLQFSCYSSLKHLYKWA-IPA----------EGKKNENL------QNLLCGSGA-------------GVISKTLTYPLDLFKKRLQVGGFEHARAAFGQ-VRRYK---------GLMDCAKQ-VLQKE----GAL-GFFKGLSPSLLKAALSTGFMFFS---YEF---FC-----------------------------NVFHCMNRTASQR------------------------------------------------------------------
SLC25A2   -------------------------------------------------------------------------------MKSGPG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQAAIDLTA-------------------------------------------------------G----------AAGGTACV-LTGQPFDTIKVKMQT-----------------------------------------------------------FPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAK------L-SDLQTAAAGSFASAF-AAL---ALCPTELVKCRLQTMYEM---------E-------------------------MSGKIAKS-HNTI-----WSVVKGI-LKKD--GP----------LGFYHGLSSTLLQEVPGY-FFFFGGYELSRSFF---------A-SGRSK---DELGPVHL------MLSGGVA-------------GICLWLVVFPVDCIKSRIQVLSMY-------GKQ---A---------GFIGTLLS-VVRNE----GIV-ALYSGLKATMIRAIPANGALFVA---YE-----------------------------------YSRKMM---------------------------------------------------MKQLEAY---------------
SLC25A20  -------------------------------------------------------------------------------MADQPK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PISPLKNLLA-------------------------------------------------------G----------GFGGVCLV-FVGHPLDTVKVRLQTQPPSLP----------------------------------------------------GQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK----HPEDV------L-SYPQLFAAGMLSGVF-TTG---IMTPGERIKCLLQ----I---------Q-------------------------ASSGESKY-TGTL------DCAKKL-YQEF--GI----------RGIYKGTVLTLMRDVPAS-GMYFMTYEWLKNIF---------TPEGKRV---SELSAPRI------LVAGGIA-------------GIFNWAVAIPPDVLKSRFQTAPPG-------KYP---N---------GFRDVLRE-LIRDE----GVT-SLYKGFNAVMIRAFPANAACFLG---FE-----------------------------------VAMKFLN-----------------WA-------------------------------TPNL------------------
SLC25A21  -------------------------------------------------------------------------------MSAKPE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSLVREASRQIVA-------------------------------------------------------G----------GSAGLVEI-CLMHPLDVVKTRFQIQRCAT------------------------------------------------------DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVS-------------LSPALTFAIAGLGSGLT-EAI---VVNPFEVVKVGLQ-------------ANRNTFAE-------------------Q---PST-----V------GYARQI-IKKEGWGL----------QGLNKGLTATLGRHGVFN-MVYFGFYYNVKNMIP---VNKDPILEFWRK-----------------FGIGLLS-------------GTIASVINIPFDVAKSRIQ-GPQPV-----PGEIK-YR---------TCFKTMAT-VYQEE----GIL-ALYKGLLPKIMRLGPGGAVMLLV---YE-------------------------------------------------------------------------------YTYSWLQENW-------------------------
SLC25A22  ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADKQISLP------------------------------------------------------AKLIN-------------------------------------------------------G----------GIAGLIGV-TCVFPIDLAKTRLQNQQN--------------------------------------------------------GQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQ------------KLTLLKEMLAGCGAGTC-QVI---VTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQ----GGAQPS---------VEAPAAP--RPTA-----TQLTRDL-LRSR--GI----------AGLYKGLGATLLRDVPFS-VVYFPLFANLNQLG---------RPASEE------KSPFYVS-----FLAGCVA-------------GSAAAVAVNPCDVVKTRLQSLQRGV------NEDT-YS---------GILDCARK-ILRHE----GPS-AFLKGAYCRALVIAPLFGIAQVV---Y----------------------------------------------------------------------------------FLGIAESL---LGLLQDPQA-------------
SLC25A23  ------------------MRGSPGDAERR--QRWGRLFE--------ELDSNKDGRV-----DVHELRQGLARLG---GGNPDPGAQQGISSEGDADPDGGLDLEE---FSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQ-----------------------------------SFRALGISISLEQAEK--ILHSMDRDGTMT-----------------------------------------------------------IDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTV-----PDE-------FSKQEKLTGMWWKQLVA-------------------------------------------------------G----------AVAGAVSR-TGTAPLDRLKVFMQVH---------------------------------------------------------ASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILG----QQETL--------HVQERFVAGSLAGAT-AQT---IIYPMEVLKTRLT-----------------------------------------LRRTGQY-KGLL------DCARRI-LERE--GP----------RAFYRGYLPNVLGIIPYA-GIDLAVYETLKNWWLQQ-YSH----------DSADPGILVL------LACGTIS-------------STCGQIASYPLALVRTRMQAQASIE-----GGPQLSML---------GLLRHILS----QE----GMR-GLYRGIAPNFMKVIPAVSISYVV---YE-----------------------------------NMKQAL-GVTSR-------------------------------------------------------------------
SLC25A24  --------MLRWLRDFVLPTAACQDAEQP--TRYETLFQ--------ALDRNGDGVV-----DIGELQEGLRNLGIPLGQD----AEEKIFTTGDVNKDGKLDFEE---FMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQ-----------------------------------SLQTLGLTISEQQAEL--ILQSIDVDGTMT-----------------------------------------------------------VDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI-----PDE-------FTEDEKKSGQWWRQLLA-------------------------------------------------------G----------GIAGAVSR-TSTAPLDRLKIMMQVH---------------------------------------------------------GSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE----EGQKI--------GTFERFISGSMAGAT-AQT---FIYPMEVMKTRLA-----------------------------------------VGKTGQY-SGIY------DCAKKI-LKHE--GL----------GAFYKGYVPNLLGIIPYA-GIDLAVYELLKSYWLDN-FAK----------DSVNPGVMVL------LGCGALS-------------STCGQLASYPLALVRTRMQAQAMLE-----GSPQLNMV---------GLFRRIIS----KE----GIP-GLYRGITPNFMKVLPAVGISYVV---YE-----------------------------------NMKQTL-GVTQK-------------------------------------------------------------------
SLC25A25  ------------MLCLCLYVPVIGEAQTE--FQY---FESKGLP--AELKSIFKLSVFIPSQEFSTYRQ----------------WKQKIVQAGDKDLDGQLDFEE---FVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQ-----------------------------------SLRDLGVKISEQQAEK--ILKSMDKNGTMT-----------------------------------------------------------IDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV-----PDE-------FTVEERQTGMWWRHLVA-------------------------------------------------------G----------GGAGAVSR-TCTAPLDRLKVLMQVH---------------------------------------------------------ASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS----DQETL--------RIHERLVAGSLAGAI-AQS---SIYPMEVLKTRMA-----------------------------------------LRKTGQY-SGML------DCARRI-LARE--GV----------AAFYKGYVPNMLGIIPYA-GIDLAVYETLKNAWLQH-YAV----------NSADPGVFVL------LACGTMS-------------STCGQLASYPLALVRTRMQAQASIE-----GAPEVTMS---------SLFKHILR----TE----GAF-GLYRGLAPNFMKVIPAVSISYVV---YE-----------------------------------NLKITL-GVQSR-------------------------------------------------------------------
SLC25A26  -----------------------MDR---------------------------PGFVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALVA-------------------------------------------------------G----------GVAGVSVD-LILFPLDTIKTRLQSPQG-------------------------------------------------------FSKA---------------GGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFL----HADSSSY-------LTPMKHMLAASAGEVV-ACL---IRVPSEVVKQRAQ-------------V-------------------------------SAS-TRTF------QIFSNI-LYEE--GI----------QGLYRGYKSTVLREIPFS-LVQFPLWESLKALWSWR-------------------QDHVVDSW-QSAVCGAFA-------------GGFAAAVTTPLDVAKT------RITLA--KAGSSTADG---------NVLSVLHG-VWRSQ----GLA-GLFAGVFPRM------AAISLGG---FI-----------------------------------FLGAYDRTHSLLLEVGRKSP-----------------------------------------------------------
SLC25A27  -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSVPEEEERLLP--------------------------------------LTQRWPRASKFLL-------------------------------------------------------S----------GCAATVAE-LATFPLDLTKTRLQMQGEAAL---------------------------------------------ARLGDGARESAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDE----------HYPLWKSVIGGMMAGVI-GQF---LANPTDLVKVQMQ-------------MEGKRKL---------------------EGKPLRF-RGVH------HAFAKI-LAEG--GI----------RGLWAGWVPNIQRAALVN-MGDLTTYDTVKHYL----VLNTPL-----------EDNIMTH-----GLSSLCS-------------GLVASILGTPADVIKSRIMNQPRDK-----QGRGLLYK---------SSTDCLIQ-AVQGE----GFM-SLYKGFLPSWLRMTPWSMVFWLT---YE-----------------------------------KIREMSGVS-------------------------------------------------PF-------------------
SLC25A28  -----------------------MELEGR-----------------------GAGGVA----------------------------------GGPAAGPGRSPGESA-LLDGWLQ-----------------------------------------------------------------------------------RGVGRGAGGGE--------------------------AGAC-----------------------RPPVRQDPDSGPDYEALPAGATV-----------------------------------------------TTHMVA-------------------------------------------------------G----------AVAGILEH-CVMYPIDCVKTRMQSLQP-------------------------------------------------------DPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNS-------------HIANGAAGCVA-TLLHDAAMNPAEVVKQRMQ-------------MY-----------------------------NSPY-HRVT------DCVRAV-WQNE--GA----------GAFYRSYTTQLTMNVPFQ-AIHFMTYEFLQEHFNPQ-RRY-------------NPSSHVLS--------GACA-------------GAVAAAATTPLDVCKTLLNTQESLALN---SHITGHIT---------GMASAFRT-VYQVG----GVT-AYFRGVQARVIYQIPSTAIAWSV---YE-----------------------------------FFKYLITKRQEEWRAGK--------------------------------------------------------------
SLC25A29  -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALDFLA-------------------------------------------------------G----------CAGGVAGV-LVGHPFDTVKVRLQVQSV--------------------------------------------------------EKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDS-------------P---LNQFLAGAAAGAI-QCV---ICCPMELAKTRLQ----L---------Q-------------------------DAGPARTY-KGSL------DCLAQI-YGHE--GL----------RGVNRGMVSTLLRETPSF-GVYFLTYDALTRALG-------CEPGDRL-------LVPKL------LLAGGTS-------------GIVSWLSTYPVDVVKSRLQADGLR-------GAPR-YR---------GILDCVHQ-SYRAE----GWR-VFTRGLASTLLRAFPVNAATFAT---VT-----------------------------------VVLTYARGEEAG--PEG-EAVPAAPA-------------------------------GPALAQPSSL------------
SLC25A3   ------------------MFSSVAHLARA--------------------------------NPFNTPHLQLVHDGLGDLRSSSPGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGQPRRPRNLAAAAVEEQYSC-----------DYG-------------------------------SGRFFI----------------------------------LCGLG----------------G----------IISCGTTH-TALVPLDLVKCRMQV-----------------------------------------------------------DPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTY-------LWRTSLYLAASASAEFF-ADI---ALAPMEAAKVRIQ--------------------------------T-----------QPGY-ANTL-----RDAAPKM-YKEE--GL----------KAFYKGVAPLWMRQIPYT-MMKFACFERTVEALYKF-----VVPKPRS--ECSKPEQLVVT-----FVAGYIA-------------GVFCAIVSHPADSVVSVLNKEKGSSASL----------------------------VLKRL----GFK-GVWKGLFARIIMIGTLTALQWFI---YD-----------------SVKVYFRLPRPPPPEMPESLKKKLGLTQ---------------------------------------------------------------------
SLC25A30  -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAL-------------------------------------------NW---KPFVY-------------------------------------------------------G----------GLASITAE-CGTFPIDLTKTRLQIQGQTND---------------------------------------------AKF-----KEIRYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDE----------TLPI--NVICGILSGVI-SST---IANPTDVLKIRMQ-------------AQSN-TI---------------------QG-------GMI------GNFMNI-YQQE--GT----------RGLWKGVSLTAQRAAIVV-GVELPVYDITKKHL----ILSGLM-----------GDTVYTH-----FLSSFTC-------------GLAGALASNPVDVVRTRMMNQRVLR-----DGRCSGYT---------GTLDCLLQ-TWKNE----GFF-ALYKGFWPNWLRLGPWNIIFFVT---YE-----------------------------------QLKKLDL------------------------------------------------------------------------
SLC25A31  ------------------MHREPAKKKAE-----KRLFD----------------------------------------------------------------------------------ASSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKDLLA-------------------------------------------------------G----------GVAAAVSK-TAVAPIERVKLLLQVQAS---------------------------------------------------SKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMS--GVNKEKQ-----FWRWFLANLASGGAAGAT-SLC---VVYPLDFARTRLG-------------V-----------------------DIGKGPEERQF-KGLG------DCIMKI-AKSD--GI----------AGLYQGFGVSVQGIIVYR-ASYFGAYDTVKGL----------LP------KPKKTPFLVS------FFIAQVV-------------TTCSGILSYPFDTVRRRMMMQSGE-------A-KRQYK---------GTLDCFVK-IYQHE----GIS-SFFRGAFSNVLRGT-GGALVLVL---YD-----------------------------------KIKEFF-HIDIGGR-----------------------------------------------------------------
SLC25A32  ------------------MTGQGQSASGS--SAWSTVFR----------------HV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R----------------------------------------------------------YENLIA-------------------------------------------------------G----------VSGGVLSN-LALHPLDLVKIRFAVSDGL------------------------------------------------------ELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEG---RAERL--------EATEYLVSAAEAGAM-TLC---ITNPLWVTKTRLM-------------LQY---------------------DAVVNSPHRQY-KGMF------DTLVKI-YKYE--GV----------RGLYKGFVPGLFGT-SHG-ALQFMAYELLKLKYNQH-INR--LP------EAQLSTV-------EYISVAALS-------------KIFAVAATYPYQVVRARLQDQ------------HMFYS---------GVIDVITK-TWRKE----GVG-GFYKGIAPNLIRVTPACCITFVV---YE-----------------------------------NVSHFLLDLREKRK-----------------------------------------------------------------
SLC25A33  ------------------MATGGQQKENT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLHLFA-------------------------------------------------------G----------GCGGTVGA-IFTCPLEVIKTRLQSSRLAL-RTVYYPQVHL---------------------------------GTISGAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIV------------HIFSAGSAAFI-TNS---LMNPIWMVKTRMQ-------------L-----------------------EQ-KVRGSKQM--NTL------QCARYV-YQTE--GI----------RGFYRGLTASYAGI-SET-IICFAIYESLKKYLKEA-PLA-SSANGTE----KNSTSFFGL-----MAAAALS-------------KGCASCIAYPHEVIRTRLREEGTK---------YKSFV---------QTARLVFR----EE----GYL-AFYRGLFAQLIRQIPNTAIVLST---YE-----------------------------------LIVYLLEDRTQ--------------------------------------------------------------------
SLC25A34  --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METVPPAVDLVL-------------------------------------------------------G----------ASACCLAC-VFTNPLEVVKTRLQLQGELQ----------------------------------------------ARGT----YPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGL----------------TQQPGGTVVAGAVAGAL-GAF---VGSPAYLIKTQLQ-------------AQTVAAV--------------------AVGHQHNH-QTVL------GALETI-WRQQ--GL----------LGLWQGVGGAVPRVMVGS-AAQLATFASAKAWV----QKQQWLP----------EDSWLVA-----LAGGMIS-------------SIAVVVVMTPFDVVSTRLYNQPVDT-----AGRGQLYG---------GLTDCMVK-IWRQE----GPL-ALYKGLGPAYLRLGPHTILSMLF---WD-----------------------------------ELRKLAGRAQHK--------------------------------------------------GT---------------
SLC25A35  ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFLM-------------------------------------------------------S----------GLAACGAC-VFTNPLEVVKTRMQLQGELQ----------------------------------------------APGT----YQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEG----------THSPARSAAAGAMAGVM-GAY---LGSPIYMVKTHLQ-------------AQAASEI--------------------AVGHQYKH-QGMF------QALTEI-GQKH--GL----------VGLWRGALGGLPRVIVGS-STQLCTFSSTKDLL----SQWEIFP----------PQSWKLA-----LVAAMMS-------------GIAVVLAMAPFDVACTRLYNQPTDA-----QGKNRVPKF--------SATSC------SAS----APL-LGTK-----------------------------------------------------------DVRIVKGQTGHQLFKVTQAP-----------------------------------GCSPILLGTQS-------------
SLC25A36  -----------------------MSQRDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVHLFA-------------------------------------------------------G----------GCGGTVGA-ILTCPLEVVKTRLQSSSV----TLYISEVQL---------------------------------NTMAGASVNR--VVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV------------HMISAAMAGFT-AIT---ATNPIWLIKTRLQ-------------L-----------------------DA-RNRGERRM--GAF------ECVRKV-YQTD--GL----------KGFYRGMSASYAGI-SET-VIHFVIYESIKQKLLEY-KTA-STMENDEE-SVKEASDFVGM-----MLAAATS-------------KTCATTIAYPHEVVRTRLREEGTK---------YRSFF---------QTLSLLVQ----EE----GYG-SLYRGLTTHLVRQIPNTAIMMAT---YE-----------------------------------LVVYLLNG-----------------------------------------------------------------------
SLC25A37  -----------------------MELR--------------------------SGSV------------------------------------GSQAVARRMDGDS------------------------------------------------------------------------------------------------RDGGGG-----------------------------------------------------------KDATGSEDYENLPTSASV-----------------------------------------------STHMTA-------------------------------------------------------G----------AMAGILEH-SVMYPVDSVKTRMQSLSP-------------------------------------------------------DPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNS-------------HLANGIAGSMA-TLLHDAVMNPAEVVKQRLQ-------------MY-----------------------------NSQH-RSAI------SCIRTV-WRTE--GL----------GAFYRSYTTQLTMNIPFQ-SIHFITYEFLQEQVNPH-RTY-------------NPQSHIIS--------GGLA-------------GALAAAATTPLDVCKTLLNTQENVALS--LANISGRLS---------GMANAFRT-VYQLN----GLA-GYFKGIQARVIYQMPSTAISWSV---YE-----------------------------------FFKYFLTKRQLENRAPY--------------------------------------------------------------
SLC25A38  --------------------------------------------------------MI---------------------QNSRPSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQPQ----------DVGDTV---------------------ETLMLHPVIKAFL------------------------------------------------------CG----------SISGTCST-LLFQPLDLLKTRLQTLQPSD------------------------------------------------------HGSRRVGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGH-------------PPTALESVMLGVGSRSV-AGV---CMSPITVIKTRYE-------------------------SG-------------KYGYESIY-----------AALRSI-YHSE--GH----------RGLFSGLTATLLRDAPFS-GIYLMFYNQTKNIVPHDQVDATLIP--------------ITN-----FSCGIFA-------------GILASLVTQPADVIKTHMQLYPLK------------FQ---------WIGQAVTL-IFKDY----GLR-GFFQGGIPRALRRTLMAAMAWTV---YE-----------------------------------EMMAKMGLKS---------------------------------------------------------------------
SLC25A39  --------------------------------------------------------M----------------------ADQDPA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GISPLQQMVA-------------------------------------------------------S----------GTGAVVTS-LFMTPLDVVKVRLQSQRPSMASEL-MPSSRLWSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL------------TSDLYAPMVAGALARLG-TVT---VISPLELMRTKLQ-------------AQHVSYRELG------------------------------------ACVRTA-VAQG--GW----------RSLWLGWGPTALRDVPFS-ALYWFNYELVKSWL-----NG-FRPKD--------QTSVGMS-----FVAGGIS-------------GTVAAVLTLPFDVVKTQRQVALGAM------EAVR-VN--P--LHVDSTWLLLRR-IRAES----GTK-GLFAGFLPRIIKAAPSCAIMIST---YE-----------------------------------FGKSFFQRLNQDRLLGG--------------------------------------------------------------
SLC25A4   ------------------------------------MGD---------------------------------------------------------------------------------HAWSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKDFLA-------------------------------------------------------G----------GVAAAVSK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLG--GVDRHKQ-----FWRYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKGAAQREF-HGLG------DCIIKI-FKSD--GL----------RGLYQGFNVSVQGIIIYR-AAYFGVYDTAKGM----------LP------DPKNVHIFVS------WMIAQSV-------------TAVAGLVSYPFDTVRRRMMMQSGRK-----GA-DIMYT---------GTVDCWRK-IAKDE----GAK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------EIKKYV-------------------------------------------------------------------------
SLC25A40  ---------------------------------------------------------------------------------MDPET---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGQ-----------------------EIIKVTPLQQMLA-------------------------------------------------------S----------CTGAILTS-VIVTPLDVVKIRLQAQN-------------------NPLPK-----GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLG------------ENETCIPIVAGIVARFG-AVT---VISPLELIRTKMQ-------------SKKFSYVELH------------------------------------RFVSKK-VSED--GW----------ISLWRGWAPTVLRDVPFS-AMYWYNYEILKKWLC--EKSGLYEP------------TFMIN-----FTSGALS-------------GSFAAVATLPFDVVKTQKQTQLWTY------ESHK-ISM-P--LHM-STWIIMKN-IVAKN----GFS-GLFSGLIPRLIKIAPACAIMIST---YE-----------------------------------FGKAFFQKQNVRRQQY---------------------------------------------------------------
SLC25A41  ------------------MGAQPGEPQNTC-SRIQTLFR----------------RV--------------KTLLIKAPPPPQPPPPPPSWNPGCTHVYG----------------------YAFGHMHDNNLEHLPSQQV------------------------------------------------------------------------------------------------------------------------------------------------------------LDTGEQLMV-----PVE-------VLEVDNKEAL-WKFLLS-------------------------------------------------------G----------AMAGAVSR-TGTAPLDRAKVYMQVY---------------------------------------------------------SSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCG----IQGSP--------PFQERLLAGSLAVAI-SQT---LINPMEVLKTRLT-----------------------------------------LRRTGQY-KGLL------DCARQI-LQRE--GT----------RALYRGYLPNMLGIIPYA-CTDLAVYEMLQCFWVKS--GR----------DMGDPSGLVS------LSSVTLS-------------TTCGQMASYPLTLVRTRMQAQDTVE-----GS-NPTMR---------GVLQRILA----QQ----GWL-GLYRGMTPTLLKVLPAGGISYVV---YE-----------------------------------AMKKTL-GI----------------------------------------------------------------------
SLC25A42  ------------------MGNGVKEGPVR-------------------------------------------------LHED----AEAVLSSSVSSK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDHRQV-----------------------------------------------------LSSLLS-------------------------------------------------------G----------ALAGALAK-TAVAPLDRTKIIFQVS---------------------------------------------------------SKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEAL--------PPWPRLFAGALAGTT-AAS---LTYPLDLVRARMA-----------------------------------------VTPKEMY-SNIF------HVFIRI-SREE--GL----------KTLYHGFMPTVLGVIPYA-GLSFFTYETLKSLHREY-SGR-RQPYPFER-----------------MIFGACA-------------GLIGQSASYPLDVVRRRMQT-AGVT-----GYPRASIA---------RTLRTIVR----EE----GAVRGLYKGLSMNWVKGPIAVGISFTT---FD-----------------------------------LMQILLRHLQS--------------------------------------------------------------------
SLC25A43  ------------------MATWRRDGRLT------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQRLLC-------------------------------------------------------A----------GLAGTLSL-SLTAPLELATVLAQVG---------------------------------------------------------VVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLG------------HISQWSSIMAGSLAGMV-STI---VTYPTDLIKTRLI-------------M--------------------------QNILEPSY-RGLL------HAFSTI-YQQE--GF----------LALYRGVSLTVVGALPFS-AGSLLVYMNLEKIWNGP-RDQFSLP--------------------QNFANVCLA-------------AAVTQTLSFPFETVKRKMQAQSPYLPH--SGGVDVHFS---------GAVDCFRQ-IVKAQ----GVL-GLWNGLTANLLKIVPYFGIMFST---FEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL-------------------------------------------------------------
SLC25A44  -----------------------MEDKRNI-------------------------------------------------------------------------------------------------------------QIIE----------------------------------------------------------------------------------------------------------------------------------------------------WEH---LD---------------------------------KKKFYV----------------------------------------------------F--G----------VAMTMMIR-VSVYPFTLIRTRLQVQ---------------------------------------------------------KGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLI-SGQCYVTTYELTRKFVADYS-------------QSNTVKSLVAGGSASLV-AQS---ITVPIDVVSQHLM-------------MQRKGEKMGRF----------------QVRGNPEG-QGVVAFGQTKDIIRQI-LQAD--GL----------RGFYRGYVASLLTYIPNS-AVWWPFYHFYAEQLSYL--------------CPKECPHIVFQ-----AVSGPLA-------------AATASILTNPMDVIRTRVQVEGKN-----------------------SIILTFRQ-LMAEE----GPW-GLMKGLSARIISATPSTIVIVVG---YE-----------------------------------SLKKLSLRPELVDSRHW--------------------------------------------------------------
SLC25A45  ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVEEFVA-------------------------------------------------------G----------WISGALGL-VLGHPFDTVKVRLQTQ------------------------------------------------------------TTYRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQ-----PP-SYMHIFLAGCTGGFL-QAY---CLAPFDLIKVRLQ----N---------QTEPRAQ-------------------PGSPPPRY-QGPV------HCAASI-FREE--GP----------RGLFRGAWALTLRDTPTV-GIYFITYEGLCRQY---------TPEGQN------PSSATV------LVAGGFA-------------GIASWVAATPLDMIKSRMQMDGL--------RRRV-YQ---------GMLDCMVS-SIRQE----GLG-VFFRGVTINSARAFPVNAVTFLS---YE-----------------------------------YLLRWWG------------------------------------------------------------------------
SLC25A46  -----------------------MHPRRPD------GFDGLG-YRGGARDEQGFGGAFPA-RSFSTGSD------LGHWVTTPPDIP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSRNLH--------------WGEKS-PPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAG----------------------------------------------------F--G---------IGLASLFTENVLAHPCIVLRRQCQVNYHAQHYHL------------TPF-----------------------------------------TVINIMYSFNKTQGPRALWKGMGSTFI----VQGVTLGAEGIISEFTPLPREVLHKWS------PKQIGEHLLLKSLTYVV-AMP-FYSASLIETVQSEII--------RDN--------------------------------------TGIL--ECVKEGIGRV------IGM-GVPHSKRL-LPLLSLIFPTVLHG-----VLHYIISSVIQKFVLLI-LKRKTYNSHLA--ESTSPVQSMLDAYFPELIANFAA-------------SLCSDVILYPLETVLHRLHIQGTRT---IIDNTDLGYEVLPINTQYEGMRDCINT-IRQEE----GVF-GFYKGFGAVIIQYTLHAAVLQITKIIYS--------------T--------------------LLQNNI-------------------------------------------------------------------------
SLC25A47  ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDFVA-------------------------------------------------------G----------AIGGVCGV-AVGYPLDTVKVRIQTE------------------------------------------------------------PKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK------P-TKADITLSGCASGLV-RVF---LTSPTEVAKVRLQ----T---------QTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKY-RGPL------HCLATV-AREE--GL----------CGLYKGSSALVLRDGHSF-ATYFLSYAVLCEWL---------SPAGHSR-----PDVPGV------LVAGGCA-------------GVLAWAVATPMDVIKSRLQADGQ--------GQRR-YR---------GLLHCMVT-SVREE----GPR-VLFKGLVLNCCRAFPVNMVVFVA---YE-----------------------------------AVLRLARGLLT--------------------------------------------------------------------
SLC25A48  -------------------------------------------------------------------------------MG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SFQLEDFAA-------------------------------------------------------G----------WIGGAASV-IVGHPLDTVKTRLQAG------------------------------------------------------------VGYGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEAS-----PPRTLSDLLLASMVAGVV-SVG---LGGPVDLIKIRLQ----M---------QTQPFRD-----------------------------GGE------HRMTTV-F------------------------------------------------------------PGPHL-----------------------------------------------------------------------------------------CM--------------------------------------------------------------------------------------------------------------------------------------------------------------
SLC25A49  MGASDPEVAPWARGGAAGMAGAGAGAGARG-----------G----------AAAGVEAR------------------ARDPPPA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRA-----------------------------HPRHPRPAAQPSA----------------------------RRMDGGSGGLGS---------------GDNAPTTEALFVALGAGVT-ALSHPLLYVKLLIQVGHEPMPPTL----------------------GTNVLG---------------------RKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLM----SNALSTVTRGSMKKVF-PPDEIEQVSN---KDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCM-------------VQ-------------------------FVGREAKY-SGVL------SSIGKI-FKEE--GL----------LGFFVGLIPHLLGD-----VVFLWGCNLLAHFINAY------------------------------LVDDSFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGL-----QAGLPPYS--P---VFKSWIHCWK--YLSVQ----G---QLFRGSSLLFRRVSSGSCFAL------------------------------------------E------------------------------------------------------------------------------
SLC25A5   ------------------------------------MTD---------------------------------------------------------------------------------AAVSF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKDFLA-------------------------------------------------------G----------GVAAAISK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQ-----FWLYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKAGAEREF-RGLG------DCLVKI-YKSD--GI----------KGLYQGFNVSVQGIIIYR-AAYFGIYDTAKGM----------LP------DPKNTHIVIS------WMIAQTV-------------TAVAGLTSYPFDTVRRRMMMQSGRK-----GT-DIMYT---------GTLDCWRK-IARDE----GGK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------EIKKYT-------------------------------------------------------------------------
SLC25A50  ------------------MADA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASQ---------------------------------------------------------------------VLLGSGLT-ILSQPLMYVKVLIQVGYEPLPPTI----------------------GRNIFG---------------------RQVCQLPGLFSYAQHIASIDGRRGLFTGLTPRLC----SGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIKETTREMIARSAATLITHPFHVITLRSM-------------VQ-------------------------FIGRESKY-CGLC------DSIITI-YREE--GI----------LGFFAGLVPRLLGD-----ILSLWLCNSLAYLVNTY------------------------------ALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGL-----AGGCPPYS--P---IYTSWIDCWC--MLQKE----G---NMSRGNSLFFRKVPFGKTYCC------------------------------------------DLKMLI-------------------------------------------------------------------------
SLC25A51  ------------------MMDSEAHEKRPP-------------------------------------------ILTSSKQDISPHI----------------------------------------------------TNVGE----------------------------------------------------------------------------------------------------------------------------------------------------MKH-----------------------------------------YLC-------------------------------------------------------G----------CCAAFNNV-AITFPIQKVLFRQQLYGIKTRDAI------------------LQ---------------------------------------------LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLH------KHVS------APEFATSGVAAVLAGTT-EAI----FTPLERVQTLLQ----------------------------------------DHKHHDKF-TNTY------QAFKAL--KCH--GI-G-----E----YYRGLVPILFRNGLSN-VLFFGLRGPIKEHLP----------------TATTHSAHLVND----FICGGLL-------------GAMLGFLFFPINVVKTRIQSQIGGE-----------FQ------SFPKVF---QK-IWLERDR--KLI-NLFRGAHLNYHRSLISWGIINAT---YEFL----------------------------------LKVI--------------------------------------------------------------------------
SLC25A52  --------MPFMRKILSNMIDSEAHEKRPP-------------------------------------------ILTSSKQDISPHI----------------------------------------------------TNVGE----------------------------------------------------------------------------------------------------------------------------------------------------MKH-----------------------------------------YLC-------------------------------------------------------G----------CCAAFNNV-AITYPIQKVLFRQQLYGIKTRDAV------------------LQ---------------------------------------------LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLR------KHVR------APEFATHGVAAVLAGTA-EAI----FTPLERVQTLLQ----------------------------------------NHKHHDKF-TNTY------QAFKAL--KCH--GI-G-----E----YYRGLVPILFRNGLSN-VLFFGLRGPIKEHLP----------------TATTHSAHLVND----FIGGGLL-------------GAMLGFLCFPINVVKTRLQSQIGGE-----------FQ------SFPKVF---QK-IWLERDR--KLI-NLFRGAHLNYHRSLISWGIINAT---YEFL----------------------------------LKFI--------------------------------------------------------------------------
SLC25A53  ----------------------------------------------------------------------------MGEQNHSPG--------------------------------------------------------KE----------------------------------------------------------------------------------------------------------------------------------------------------LQHRT-------------------------RAEAPGKKSWHSQAYAL-------------------------------------------------------G----------AVSNFMST-FLTFPIYKVVFRQQIHAMAVSEAV------------------RQ---------------------------------------------LWHEGPQYFYRGIYPPLLSKTLQGTLLFGTYDSLLCFLSPV---GPHTL------GHRWA----AGLMSGVV-EAV---ALSPFERVQNVLQ----------------------------------------DGRKQARF-PSTF------SILKEF--NSY--GLWG-----RLSLGYYRGFWPVLARNSLGS-ALYFSFKDPIQDGL------------------AEQGLPHWVPA----LVSGSVN-------------GTITCLVLYPLIVLVANMQSHIG-------------WQ------NMPSLWASAQD-VWNTRGR--KLL-LIYRGGSLVILRSSVTWGLTTAI---HDFLQRKSH----------SRK---------------ELKTD--------------------------------------------------------------------------
SLC25A6   ------------------------------------MTE---------------------------------------------------------------------------------QAISF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKDFLA-------------------------------------------------------G----------GIAAAISK-TAVAPIERVKLLLQVQHA---------------------------------------------------SKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKHTQ-----FWRYFAGNLASGGAAGAT-SLC---FVYPLDFARTRLA-------------A-----------------------DVGKSGTEREF-RGLG------DCLVKI-TKSD--GI----------RGLYQGFSVSVQGIIIYR-AAYFGVYDTAKGM----------LP------DPKNTHIVVS------WMIAQTV-------------TAVAGVVSYPFDTVRRRMMMQSGRK-----GA-DIMYT---------GTVDCWRK-IFRDE----GGK-AFFKGAWSNVLRGM-GGAFVLVL---YD-----------------------------------ELKKVI-------------------------------------------------------------------------
SLC25A7   -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGLTA--------------------------------------SDVHPTLGVQLFS-------------------------------------------------------A----------GIAACLAD-VITFPLDTAKVRLQVQGE------------------------------------------------CPTS----SVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLT-AGKET----------APSLGSKILAGLTTGGV-AVF---IGQPTEVVKVRLQ-------------AQSHLH-----------------------GIKPRY-TGTY------NAYRII-ATTE--GL----------TGLWKGTTPNLMRSVIIN-CTELVTYDLMKEAF----VKNNIL-----------ADDVPCH-----LVSALIA-------------GFCATAMSSPVDVVKTRFINSPPGQ-----------YK---------SVPNCAMK-VFTNE----GPT-AFFKGLVPSFLRLGSWNVIMFVC---FE-----------------------------------QLKRELSKSRQTMD-------------------------------------------CAT-------------------
SLC25A8   -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGFKA--------------------------------------TDVPPTATVKFLG-------------------------------------------------------A----------GTAACIAD-LITFPLDTAKVRLQIQGESQG--------------------------------------------PVRAT----ASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEH----------A-SIGSRLLAGSTTGAL-AVA---VAQPTDVVKVRFQ-------------AQARAG------------------------GGRRY-QSTV------NAYKTI-AREE--GF----------RGLWKGTSPNVARNAIVN-CAELVTYDLIKDAL----LKANLM-----------TDDLPCH-----FTSAFGA-------------GFCTTVIASPVDVVKTRYMNSALGQ-----------YS---------SAGHCALT-MLQKE----GPR-AFYKGFMPSFLRLGSWNVVMFVT---YE-----------------------------------QLKRALMAACTSRE-------------------------------------------APF-------------------
SLC25A9   -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGLKP--------------------------------------SDVPPTMAVKFLG-------------------------------------------------------A----------GTAACFAD-LVTFPLDTAKVRLQIQGENQA---------------------------------------------VQTA----RLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADN----------S-SLTTRILAGCTTGAM-AVT---CAQPTDVVKVRFQ-------------ASIHLGP---------------------SRSDRKY-SGTM------DAYRTI-AREE--GV----------RGLWKGTLPNIMRNAIVN-CAEVVTYDILKEKL----LDYHLL-----------TDNFPCH-----FVSAFGA-------------GFCATVVASPVDVVKTRYMNSPPGQ-----------YF---------SPLDCMIK-MVAQE----GPT-AFYKGFTPSFLRLGSWNVVMFVT---YE-----------------------------------QLKRALMKVQMLRE-------------------------------------------SPF-------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC25A25 27 S/L 0.000152372 rs778512097
-- SLC25A25 28 E/K 0.00145715 rs115942384
-- SLC25A25 32 T/P 0.0011395 rs769205196
-- SLC25A25 109 D/V 0.000167074 rs144383132
-- SLC25A25 131 T/M 0.000417851 rs748220703
-- SLC25A25 148 V/M 0.000521356 rs151146132
-- SLC25A25 149 A/T 0.000319068 rs752328329
-- SLC25A25 160 G/A 0.00331359 rs115948293
-- SLC25A25 315 Q/H 0.00225662 rs140777921
-- SLC25A25 432 A/V 0.00107556 rs142830945

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data