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Basic
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Structure
Seq./Align.
Variant
Phylogenetic Tree
Pathway
Disease

Detail Data SLC23A1


Basic description
Gene Name SLC23A1
Protein Name Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3)
Family SLC23
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 5 8 0 5 9 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550        560        570        580        590 
MRAQEDLEGR TQHETTRDPS TPLPTEPKFD MLYKIEDVPP WYLCILLGFQ HYLTCFSGTI AVPFLLAEAL CVGHDQHMVS QLIGTIFTCV GITTLIQTTV GIRLPLFQAS AFAFLVPAKA ILALERWKCP PEEEIYGNWS LPLNTSHIWH PRIREVQGAI MVSSVVEVVI GLLGLPGALL NYIGPLTVTP TVSLIGLSVF QAAGDRAGSH WGISACSILL IILFSQYLRN LTFLLPVYRW GKGLTLLRIQ IFKMFPIMLA IMTVWLLCYV LTLTDVLPTD PKAYGFQART DARGDIMAIA PWIRIPYPCQ WGLPTVTAAA VLGMFSATLA GIIESIGDYY ACARLAGAPP PPVHAINRGI FTEGICCIIA GLLGTGNGST SSSPNIGVLG ITKVGSRRVV QYGAAIMLVL GTIGKFTALF ASLPDPILGG MFCTLFGMIT AVGLSNLQFV DMNSSRNLFV LGFSMFFGLT LPNYLESNPG AINTGILEVD QILIVLLTTE MFVGGCLAFI LDNTVPGSPE ERGLIQWKAG AHANSDMSSS LKSYDFPIGM GIVKRITFLK YIPICPVFKG FSSSSKDQIA IPEDTPENTE TASVCTKV 
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH CCCCCHHHHH HHHHHHHHHH HHHHHHHHHH CCCCCCCCCC HHHHHHHHHH HHHHCCCCCC CCCCCCCCCC CCCCCCCCCH HHHHHHHHHH HHHHHHHHHH HHHCCCCHHH HHCCCCCHHH HHHHHHHHHH HHHHHHCCCC CCCCHHHHHH HHHHHHHHHH HHHHHHHHHH CCCHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCCCC HHHCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC CCCCCCCHHH HHHHHHHHHH HHHCCCCCCC CCCCCCCEEE EEEECCHHHH HHHHHHHHHH CCCCHHHHHH HCCCCCHHHH HHHHHHHHHH HHHHHHHHCC CCCCCCCEEE HHHHHHCCCC HHHHHHHCCC CCHHCCHHHH HHHHHHHCCH HHHHHHHHHH HHHCCCCCHH HCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCC
[Overview] SLC23A1 SLC23A2 SLC23A3 
SLC23A1   ------------MRAQEDLEGRTQHETTRDPSTPLPT---------------------------------------------EP-KFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLP-LN---------TSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTVW----LLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQ-------WKAGAHANSDMSSSLKSYDFPIGMG-----IVKRITFLKYIPICPVFKGFSSSSKDQIA-----IPEDTPENTETASVCTKV
SLC23A2   MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLH---------TEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSW----LLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRK-------WKKGVGKGNKSLDGMESYNLPFGMN-----IIKKYRCFSYLPISPTFVGYTWKGLRK---------SDNSRSSDEDSQATG-
SLC23A3   ------------MSRSPLNPSQLRSVGSQDALAPLPP----------------------------------PAPQNPSTHSWDP--------LCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNSSLM-LHLCRGPSCHGLGH-WNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLT-----------------------------------------------WAPASFMC-------------------------------AP-----------------GGELQRHQLTLLSL--SSGSFRNCL------PPPRH--------HGFGC-----------------------LTQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQGLPSPFTAQEARMPQKPREKAAQVYRLPFPIQNLCPCIPQPLHCLCPLPEDPGDEEGGSSEPEEMADLLPGSGEPCPESSREGFRSQK-

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC23A1 8 E/K 0.00042063 rs138079930
-- SLC23A1 17 H/R 0.00150733 rs34521685
-- SLC23A1 22 P/L 0.000175614 rs199767403
-- SLC23A1 32 G/R 0.000326929 rs575278271
-- SLC23A1 56 F/L 0.00048184 rs372917905
-- SLC23A1 71 C/Y 0.000117907 rs749544722
-- SLC23A1 74 H/Y 0.00034192 rs569370877
-- SLC23A1 88 T/A 0.000314691 rs200631596
-- SLC23A1 100 V/M 0.000105127 rs777663460
-- SLC23A1 218 I/V 0.00150733 rs34521685
-- SLC23A1 258 M/V 0.00505726 rs35817838
-- SLC23A1 264 V/M 0.0273026 rs33972313
-- SLC23A1 421 S/A 0.999761 rs6596474
-- SLC23A1 470 T/M 0.000135598 rs116659253
-- SLC23A1 525 I/T 0.000270776 rs756378577
-- SLC23A1 526 Q/K 0.0127732 rs72552250

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
SLC23A1 SLC23A1 [plasma membrane] Vitamin C (ascorbate) metabolism

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data