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Detail Data SLC2A7
Basic description
Gene Name | SLC2A7 |
---|---|
Protein Name | Solute carrier family 2, facilitated glucose transporter member 7 (Glucose transporter type 7) (GLUT-7) |
Family | SLC2 |
Category | Cellular hexose transport |
Reaction name | - |
Reaction | - |
[Overview]
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 MENKEAGTPP PIPSREGRLQ PTLLLATLSA AFGSAFQYGY NLSVVNTPHK VFKSFYNETY FERHATFMDG KLMLLLWSCT VSMFPLGGLL GSLLVGLLVD SCGRKGTLLI NNIFAIIPAI LMGVSKVAKA FELIVFSRVV LGVCAGISYS ALPMYLGELA PKNLRGMVGT MTEVFVIVGV FLAQIFSLQA ILGNPAGWPV LLALTGVPAL LQLLTLPFFP ESPRYSLIQK GDEATARQAL RRLRGHTDME AELEDMRAEA RAERAEGHLS VLHLCALRSL RWQLLSIIVL MAGQQLSGIN AINYYADTIY TSAGVEAAHS QYVTVGSGVV NIVMTITSAV LVERLGRRHL LLAGYGICGS ACLVLTVVLL FQNRVPELSY LGIICVFAYI AGHSIGPSPV PSVVRTEIFL QSSRRAAFMV DGAVHWLTNF IIGFLFPSIQ EAIGAYSFII FAGICLLTAI YIYVVIPETK GKTFVEINRI FAKRNRVKLP EEKEETIDAG PPTASPAKET SF CCCCCCCCCC CCCCCCCCCC HHHHHHHHHH HHCHHHHCCC CCCCCCCHHH HHHHHHHHHH HHHCCCCCCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCHHHHHHH HHHHHHHHHH HHHHCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CHHHHHCHHH HHHHHHHHHH HHHHHHHHHH HHCCCCCHHH HHHHHHHHHH HHHHHHHHCC CCHHHHHHHC CCHHHHHHHH HHHHCCCCHH HHHHHHHHHH HHHHHCCCCC HHHHHCCCHH HHHHHHHHHH HHHHHHHCCC HHHHCCHHHH HHCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCCHHH HHHHHHHHHH HHHHCCCCCC HHHHHHHCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCCHHHHH HHHHHHHHHH HHHHHCHHCC CCCHHHHHHH HHHCCCCCCC HHHCCCCCCC CCCCCCCCCC CC
[Overview]
SLC2A1 -------------------------------------------------------------------------------MEPSSKKLTGRLMLAVGG-AVLGS-LQFGYNTGVINAPQKVI--------------EEFYNQTWVHRYG----ESILPTT----------------------LTTLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPES-------PRFLLINRNEENRAKSV-LKKLRGTA-DVTHDLQEMK-----EESRQMMREKKVTILELFRSP-AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV-----QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMT-IALALLEQLP--------------------------------------------------------------------------------------------------------------------------WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPY----VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF---RQGGAS-------------------QSDKTPEELF-----HPLGADSQV--------- SLC2A10 ----------------------------------MGHSPPVLPL-----CASVS-------------------------------------LL--------GG-LTFGYELAVISGALLPLQLDF-------------------------------------------------------GLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYAL-AGTPWGWRHMFGWATAPAVLQSLSLLFLPAGTDETATHKDLI-PLQG--GEAPKLGPGRPR------------------------------YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGF--HGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMD---------------------SGPSCLAVPNATGQTGL---------PGDSGLLQDSSLPPIPRTNEDQR-----EPILSTAKKTKPHPRSGDPSAP-------PRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSW---TFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ-KRRFTLS----FGHRQNS-------------------------TGIPYSRIEISAAS-- SLC2A11 --MEDELEPS---------------------------------------------------------------------LRPRTQIQGRILLLTICA-AGIGGTFQFGYNLSIINAPTLHI--------------QEFTNETWQARTG--------------------------EPLPDHLVLLMW-SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPES-------PRYLLIDCGDTEACLAA-LRRLRGSG-DLAGELEELE-----EERAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV--P-EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFT-VALCLQSSFP--------------------------------------------------------------------------------------------------------------------------WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF----LYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELH-RLN-----------------------------------FPRRAQGPTWRSLEVIQSTEL SLC2A12 --MVPVENTEGP-------SLLNQKGTAVETEGSGSRHPPWARG-----CGMFT-------------------------------------FLSSVT-AAVSG-LLVGYELGIISGALLQIKTLL-------------------------------------------------------ALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI---LSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKYMFGLVIPLGVLQAIAMYFLPPS-------PRFL-VMKGQEGAASKV-LGRLRALS-DTTEELTVIK--------SSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF--QSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFT-HICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHF---------KGISS-HSRSSLMPL-RNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDV-------P------------------AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPW---VCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELA-KVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLEC----NKLCGRGQSR-QLSPET-- SLC2A13 --MSRKASENVEYTLRSLSSLMG------ER---RRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGG-FLFGYDTGVVSGAMLLL-------------KRQL------------------------------------------SLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLA---AANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPES-------PRWL-IQKGQTQKARRI-LSQMRGNQ-TIDEEYDSIKNN--IEEEEKEVGSAGPVICRMLSYP-PTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV--EDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA-LGFVLSAQVSPRI---------TFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPV-----------NKASTNEAAWGRCENETKFKTEDIFWAYNFCP------------------TPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYG---AFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFD-NRLCTCG-------------------TSDSDEGRYIEYI--RVKGSNYHLSDNDASDVE SLC2A14 --MEFHNGGHVSGIGGFLVSLTS------R-------------------------------------------------MKPHTLAVTPALIFAITV-ATIGS-FQFGYNTGVINAPETII--------------KEFINKTLTDK------ANAPPSEV--------------------LLTNLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPES-------PRFLLINRKKEENATRI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKNHYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMGM-----NSIEPAKETTTNV----- SLC2A2 ---------------------------------------------------------------------------------MTEDKVTGTLVFTVIT-AVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINS------TDELPTISYSMNPKPTPWAEEETVAAAQLITMLW-SLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPES-------PRYLYIKLDEEVKAKQS-LKRLRGYD-DVTKDINEMR-----KEREEASSEQKVSIIQLFTNS-SYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI-----SKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMS-VGLVLLNKFS--------------------------------------------------------------------------------------------------------------------------WMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPY----VFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQ-KKSGSAH-------------------RP--KAAVEM-----KFLGATETV--------- SLC2A3 -------------MG--------------------------------------------------------------------TQKVTPALIFAITV-ATIGS-FQFGYNTGVINAPEKII--------------KEFINKTLTDK------GNAPPSEV--------------------LLTSLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPES-------PRFLLINRKEEENAKQI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKDNYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMEM-----NSIEPAKETTTNV----- SLC2A4 MPSGFQQ------IG------SE------D-------------------------------------------------GEPPQQRVTGTLVLAVFS-AVLGS-LQFGYNIGVINAPQKVI--------------EQSYNETWLGRQGPEGPSSIPPGT----------------------LTTLW-ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPES-------PRYLYIIQNLEGPARKS-LKRLTGWA-DVSGVLAELK-----DEKRKLERERPLSLLQLLGSR-THRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV-----GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMT-VALLLLERVP--------------------------------------------------------------------------------------------------------------------------AMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPY----VFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFH--RTPSLL-------------------EQEVKPSTEL-----EYLGPDEND--------- SLC2A5 --MEQQDQSM------------------------------------------------------------------------KEGRLTLVLALATLI-AAFGSSFQYGYNVAAVNSPALLM--------------QQFYNETYYGRTG--------------------------EFMEDFPLTLLW-SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPES-------PRYLLIQKKDEAAAKKA-LQTLRGWD-SVDREVAEIR-----QEDEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV--P-EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT-AALALQDTVS--------------------------------------------------------------------------------------------------------------------------WMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY----SFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFT-KMNKVSE-------------------VYPEKEELKE--------LPPVTSEQ------- SLC2A6 ---------MQE-------PLLGAEGPDYDT---FPEKPPPSPG----------------------------------DRARVGTLQNKRVFLATFA-AVLGN-FSFGYALVYTSPVIPAL-------------ERSLDPDLHLTKSQA--------------------------------------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL------PWRWLAVAGEAPVLIMILLLSFMPNS-------PRFL-LSRGRDEEALRA-LAWLRGTDVDVHWEFEQIQDNVRRQSSRVS--------WAEARAP-HVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP-PKDD---AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG-LYIHF---GP-----------------RPLSPNSTAGLESE--------SWG-----------------------------DLAQPLAAPAG----------------------------------------YLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR---------------------------------------------------- SLC2A7 --MENKEAGTP---------------------------P-PIP--------------------------------------SREGRLQPTLLLATLS-AAFGSAFQYGYNLSVVNTPHKVF--------------KSFYNETYFERHA--------------------------TFMDGKLMLLLW-SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPES-------PRYSLIQKGDEATARQA-LRRLRGHT-DMEAELEDMR-----AEARAERAEGHLSVLHLCALR-SLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGV--E-AAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLT-VVLLFQNRVP--------------------------------------------------------------------------------------------------------------------------ELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAY----SFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFA-KRNRVKL-------------------PEEKEETIDA--------GPPTASPAKETSF-- SLC2A8 --MTPEDPEETQ-------PLLG---------------PPGGSA----------------------------------PRGR-------RVFLAAFA-AALGP-LSFGFALGYSSPAIPSL-------------QRAAPPAPRLDDAAA--------------------------------------SWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVIT---AAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL------EWRWLAVLGCVPPSLMLLLMCFMPET-------PRFL-LTQHRRQEAMAA-LRFLWGSEQG--WE-----DPPIGAEQSFH--------LALLRQP-GIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKF-----KDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG-AYFKLTQGGP-----------------GNSSHVAISAPVS-------------------------------------------AQPVDASVG-----------------------------------------LAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG---AFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE-GR--------------------------------------------------------- SLC2A9 --MARKQNRNSKELG--LVPLTD------DT---SHAGP-PGPGRALLECDHLRS---------------GV------PGGRRRKDWSCSLLVASLA-GAFGSSFLYGYNLSVVNAPTPYI--------------KAFYNESWERRHG--------------------------RPIDPDTLTLLW-SVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDS-------PRYLLLEKHNEARAVKA-FQTFLGKA-DVSQEVEEVL-----AESRVQRSIRLVSVLELLRAP-YVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P-PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT-ITLTLQDHAP--------------------------------------------------------------------------------------------------------------------------WVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS-KRNKA----------------------YPPEEKIDSAVTDGKINGRP------------
Variant
check | gene name | residue number | Reference Amino Acid / Variant Amino Acid | minor allele frequency | rs number |
---|---|---|---|---|---|
-- | SLC2A7 | 6 | A/V | 0.000491208 | rs150973958 |
-- | SLC2A7 | 59 | T/N | 0.00237527 | rs143892095 |
-- | SLC2A7 | 63 | R/Q | 0.00028643 | rs148940357 |
-- | SLC2A7 | 65 | A/E | 0.00636385 | rs61744620 |
-- | SLC2A7 | 95 | V/M | 0.000270552 | rs563784708 |
-- | SLC2A7 | 135 | V/I | 0.0105068 | rs34545462 |
-- | SLC2A7 | 150 | S/R | 0.000538067 | rs372549045 |
-- | SLC2A7 | 199 | P/L | 0.00013278 | rs561149973 |
-- | SLC2A7 | 224 | R/H | 0.000105214 | rs199994353 |
-- | SLC2A7 | 224 | R/C | 0.00588859 | rs35776221 |
-- | SLC2A7 | 235 | T/A | 0.000720716 | rs113582754 |
-- | SLC2A7 | 257 | R/H | 0.000422953 | rs149017120 |
-- | SLC2A7 | 261 | R/W | 0.000786509 | rs115204359 |
-- | SLC2A7 | 261 | R/Q | 0.104139 | rs12402973 |
-- | SLC2A7 | 289 | V/M | 0.000604128 | rs144633163 |
-- | SLC2A7 | 336 | I/N | 0.00403155 | rs79764084 |
-- | SLC2A7 | 377 | E/K | 0.00119492 | rs144505778 |
-- | SLC2A7 | 382 | G/S | 0.00235607 | rs74767526 |
-- | SLC2A7 | 395 | I/T | 0.00151991 | rs199751862 |
-- | SLC2A7 | 414 | R/W | 0.000127361 | rs149870338 |
-- | SLC2A7 | 439 | I/M | 0.00172662 | rs116662431 |
-- | SLC2A7 | 453 | G/R | 0.00082316 | rs200269396 |
-- | SLC2A7 | 474 | F/I | 0.000254479 | rs146720870 |
Phylogenetic tree
Pathway
Priority | Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|---|
main | SLC2A7 | SLC2A7 [plasma membrane] | Cellular hexose transport |
Disease
Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|
No data |