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Variant
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Pathway
Disease

Detail Data SLC2A12


Basic description
Gene Name SLC2A12
Protein Name Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)
Family SLC2
Category Cellular hexose transport
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 5 8 0 5 9 0 6 0 0 6 1 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510        520        530        540        550        560        570        580        590        600        610 
MVPVENTEGP SLLNQKGTAV ETEGSGSRHP PWARGCGMFT FLSSVTAAVS GLLVGYELGI ISGALLQIKT LLALSCHEQE MVVSSLVIGA LLASLTGGVL IDRYGRRTAI ILSSCLLGLG SLVLILSLSY TVLIVGRIAI GVSISLSSIA TCVYIAEIAP QHRRGLLVSL NELMIVIGIL SAYISNYAFA NVFHGWKYMF GLVIPLGVLQ AIAMYFLPPS PRFLVMKGQE GAASKVLGRL RALSDTTEEL TVIKSSLKDE YQYSFWDLFR SKDNMRTRIM IGLTLVFFVQ ITGQPNILFY ASTVLKSVGF QSNEAASLAS TGVGVVKVIS TIPATLLVDH VGSKTFLCIG SSVMAASLVT MGIVNLNIHM NFTHICRSHN SINQSLDESV IYGPGNLSTN NNTLRDHFKG ISSHSRSSLM PLRNDVDKRG ETTSASLLNA GLSHTEYQIV TDPGDVPAFL KWLSLASLLV YVAAFSIGLG PMPWLVLSEI FPGGIRGRAM ALTSSMNWGI NLLISLTFLT VTDLIGLPWV CFIYTIMSLA SLLFVVMFIP ETKGCSLEQI SMELAKVNYV KNNICFMSHH QEELVPKQPQ KRKPQEQLLE CNKLCGRGQS RQLSPET 
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHHHCHHHHH HHHHHHHHHH HHCCCHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCHHHHH HHHHHHHHHH HHHHHHCCCH HHHHHHHHHH HHHHHHHHHH HHHHHHHHCC CHHCCCHHHH HHHHHHHHHH HHHHHHHHHH CCCCCHHHHH HHHHHHHHHH HHHHHHCCCC HHHHHHCCCH HHHHHHHHHH HCCCHHHHHH HHHHHHHHHH CCCCHHHHHC CCCCHHHHHH HHHHHHHHHH HHCCCHHHHH HHHHHHHCCC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCHHHHHHHH HHHHHHHHHH HHHHHHHCCC CCCCCCCCCH HHHHHHCCHH HCCCCCHHHH HHHHHHHHHH CCCCCCCCCC CCCCCCCCCC CCCHHHHHHH CCCCCCCCCC CCCCCHHHHH HHHHHHHHHH HHHHHHHCCC CCHHHHHHHH HCCCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCHHHH HHHHHHHHHH HHHHHHHHCH HCCCCCHHHH HHHHHCCCCC CCCCCCCCCC HHHCCCCCCC CCCCHHHHHH HHHHHCCCCC CCCCCCC
[Overview] SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A13 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A5 SLC2A6 SLC2A7 SLC2A8 SLC2A9 
SLC2A1    -------------------------------------------------------------------------------MEPSSKKLTGRLMLAVGG-AVLGS-LQFGYNTGVINAPQKVI--------------EEFYNQTWVHRYG----ESILPTT----------------------LTTLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPES-------PRFLLINRNEENRAKSV-LKKLRGTA-DVTHDLQEMK-----EESRQMMREKKVTILELFRSP-AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV-----QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMT-IALALLEQLP--------------------------------------------------------------------------------------------------------------------------WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPY----VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF---RQGGAS-------------------QSDKTPEELF-----HPLGADSQV---------
SLC2A10   ----------------------------------MGHSPPVLPL-----CASVS-------------------------------------LL--------GG-LTFGYELAVISGALLPLQLDF-------------------------------------------------------GLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYAL-AGTPWGWRHMFGWATAPAVLQSLSLLFLPAGTDETATHKDLI-PLQG--GEAPKLGPGRPR------------------------------YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGF--HGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMD---------------------SGPSCLAVPNATGQTGL---------PGDSGLLQDSSLPPIPRTNEDQR-----EPILSTAKKTKPHPRSGDPSAP-------PRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSW---TFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ-KRRFTLS----FGHRQNS-------------------------TGIPYSRIEISAAS--
SLC2A11   --MEDELEPS---------------------------------------------------------------------LRPRTQIQGRILLLTICA-AGIGGTFQFGYNLSIINAPTLHI--------------QEFTNETWQARTG--------------------------EPLPDHLVLLMW-SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPES-------PRYLLIDCGDTEACLAA-LRRLRGSG-DLAGELEELE-----EERAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV--P-EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFT-VALCLQSSFP--------------------------------------------------------------------------------------------------------------------------WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF----LYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELH-RLN-----------------------------------FPRRAQGPTWRSLEVIQSTEL
SLC2A12   --MVPVENTEGP-------SLLNQKGTAVETEGSGSRHPPWARG-----CGMFT-------------------------------------FLSSVT-AAVSG-LLVGYELGIISGALLQIKTLL-------------------------------------------------------ALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI---LSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKYMFGLVIPLGVLQAIAMYFLPPS-------PRFL-VMKGQEGAASKV-LGRLRALS-DTTEELTVIK--------SSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF--QSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFT-HICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHF---------KGISS-HSRSSLMPL-RNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDV-------P------------------AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPW---VCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELA-KVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLEC----NKLCGRGQSR-QLSPET--
SLC2A13   --MSRKASENVEYTLRSLSSLMG------ER---RRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGG-FLFGYDTGVVSGAMLLL-------------KRQL------------------------------------------SLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLA---AANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPES-------PRWL-IQKGQTQKARRI-LSQMRGNQ-TIDEEYDSIKNN--IEEEEKEVGSAGPVICRMLSYP-PTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV--EDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA-LGFVLSAQVSPRI---------TFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPV-----------NKASTNEAAWGRCENETKFKTEDIFWAYNFCP------------------TPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYG---AFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFD-NRLCTCG-------------------TSDSDEGRYIEYI--RVKGSNYHLSDNDASDVE
SLC2A14   --MEFHNGGHVSGIGGFLVSLTS------R-------------------------------------------------MKPHTLAVTPALIFAITV-ATIGS-FQFGYNTGVINAPETII--------------KEFINKTLTDK------ANAPPSEV--------------------LLTNLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPES-------PRFLLINRKKEENATRI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKNHYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMGM-----NSIEPAKETTTNV-----
SLC2A2    ---------------------------------------------------------------------------------MTEDKVTGTLVFTVIT-AVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINS------TDELPTISYSMNPKPTPWAEEETVAAAQLITMLW-SLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPES-------PRYLYIKLDEEVKAKQS-LKRLRGYD-DVTKDINEMR-----KEREEASSEQKVSIIQLFTNS-SYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI-----SKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMS-VGLVLLNKFS--------------------------------------------------------------------------------------------------------------------------WMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPY----VFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQ-KKSGSAH-------------------RP--KAAVEM-----KFLGATETV---------
SLC2A3    -------------MG--------------------------------------------------------------------TQKVTPALIFAITV-ATIGS-FQFGYNTGVINAPEKII--------------KEFINKTLTDK------GNAPPSEV--------------------LLTSLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPES-------PRFLLINRKEEENAKQI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKDNYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMEM-----NSIEPAKETTTNV-----
SLC2A4    MPSGFQQ------IG------SE------D-------------------------------------------------GEPPQQRVTGTLVLAVFS-AVLGS-LQFGYNIGVINAPQKVI--------------EQSYNETWLGRQGPEGPSSIPPGT----------------------LTTLW-ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPES-------PRYLYIIQNLEGPARKS-LKRLTGWA-DVSGVLAELK-----DEKRKLERERPLSLLQLLGSR-THRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV-----GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMT-VALLLLERVP--------------------------------------------------------------------------------------------------------------------------AMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPY----VFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFH--RTPSLL-------------------EQEVKPSTEL-----EYLGPDEND---------
SLC2A5    --MEQQDQSM------------------------------------------------------------------------KEGRLTLVLALATLI-AAFGSSFQYGYNVAAVNSPALLM--------------QQFYNETYYGRTG--------------------------EFMEDFPLTLLW-SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPES-------PRYLLIQKKDEAAAKKA-LQTLRGWD-SVDREVAEIR-----QEDEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV--P-EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT-AALALQDTVS--------------------------------------------------------------------------------------------------------------------------WMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY----SFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFT-KMNKVSE-------------------VYPEKEELKE--------LPPVTSEQ-------
SLC2A6    ---------MQE-------PLLGAEGPDYDT---FPEKPPPSPG----------------------------------DRARVGTLQNKRVFLATFA-AVLGN-FSFGYALVYTSPVIPAL-------------ERSLDPDLHLTKSQA--------------------------------------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL------PWRWLAVAGEAPVLIMILLLSFMPNS-------PRFL-LSRGRDEEALRA-LAWLRGTDVDVHWEFEQIQDNVRRQSSRVS--------WAEARAP-HVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP-PKDD---AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG-LYIHF---GP-----------------RPLSPNSTAGLESE--------SWG-----------------------------DLAQPLAAPAG----------------------------------------YLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR----------------------------------------------------
SLC2A7    --MENKEAGTP---------------------------P-PIP--------------------------------------SREGRLQPTLLLATLS-AAFGSAFQYGYNLSVVNTPHKVF--------------KSFYNETYFERHA--------------------------TFMDGKLMLLLW-SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPES-------PRYSLIQKGDEATARQA-LRRLRGHT-DMEAELEDMR-----AEARAERAEGHLSVLHLCALR-SLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGV--E-AAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLT-VVLLFQNRVP--------------------------------------------------------------------------------------------------------------------------ELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAY----SFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFA-KRNRVKL-------------------PEEKEETIDA--------GPPTASPAKETSF--
SLC2A8    --MTPEDPEETQ-------PLLG---------------PPGGSA----------------------------------PRGR-------RVFLAAFA-AALGP-LSFGFALGYSSPAIPSL-------------QRAAPPAPRLDDAAA--------------------------------------SWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVIT---AAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL------EWRWLAVLGCVPPSLMLLLMCFMPET-------PRFL-LTQHRRQEAMAA-LRFLWGSEQG--WE-----DPPIGAEQSFH--------LALLRQP-GIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKF-----KDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG-AYFKLTQGGP-----------------GNSSHVAISAPVS-------------------------------------------AQPVDASVG-----------------------------------------LAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG---AFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE-GR---------------------------------------------------------
SLC2A9    --MARKQNRNSKELG--LVPLTD------DT---SHAGP-PGPGRALLECDHLRS---------------GV------PGGRRRKDWSCSLLVASLA-GAFGSSFLYGYNLSVVNAPTPYI--------------KAFYNESWERRHG--------------------------RPIDPDTLTLLW-SVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDS-------PRYLLLEKHNEARAVKA-FQTFLGKA-DVSQEVEEVL-----AESRVQRSIRLVSVLELLRAP-YVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P-PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT-ITLTLQDHAP--------------------------------------------------------------------------------------------------------------------------WVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS-KRNKA----------------------YPPEEKIDSAVTDGKINGRP------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC2A12 87 V/L 0.00102677 rs147475994
-- SLC2A12 103 R/G 0.00275659 rs61741411
-- SLC2A12 106 R/G 0.000159108 rs61741413
-- SLC2A12 225 V/L 0.000108162 rs202023228
-- SLC2A12 259 D/E 0.000127342 rs543603312
-- SLC2A12 270 R/H 0.000115373 rs144078437
-- SLC2A12 586 P/S 0.000326298 rs200847615

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
main SLC2A12 SLC2A12 [plasma membrane] Cellular hexose transport

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data