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Detail Data SLC2A11
Basic description
Gene Name | SLC2A11 |
---|---|
Protein Name | Solute carrier family 2, facilitated glucose transporter member 11 (Glucose transporter type 10) (GLUT-10) (Glucose transporter type 11) (GLUT-11) |
Family | SLC2 |
Category | Cellular hexose transport |
Reaction name | - |
Reaction | - |
[Overview]
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 MEDELEPSLR PRTQIQGRIL LLTICAAGIG GTFQFGYNLS IINAPTLHIQ EFTNETWQAR TGEPLPDHLV LLMWSLIVSL YPLGGLFGAL LAGPLAITLG RKKSLLVNNI FVVSAAILFG FSRKAGSFEM IMLGRLLVGV NAGVSMNIQP MYLGESAPKE LRGAVAMSSA IFTALGIVMG QVVGLRELLG GPQAWPLLLA SCLVPGALQL ASLPLLPESP RYLLIDCGDT EACLAALRRL RGSGDLAGEL EELEEERAAC QGCRARRPWE LFQHRALRRQ VTSLVVLGSA MELCGNDSVY AYASSVFRKA GVPEAKIQYA IIGTGSCELL TAVVSCVVIE RVGRRVLLIG GYSLMTCWGS IFTVALCLQS SFPWTLYLAM ACIFAFILSF GIGPAGVTGI LATELFDQMA RPAACMVCGA LMWIMLILVG LGFPFIMEAL SHFLYVPFLG VCVCGAIYTG LFLPETKGKT FQEISKELHR LNFPRRAQGP TWRSLEVIQS TEL CCCCCCCCCC CCCCCCCHHH HHHHHHHHHH HHHHHCCCHH HCCCCHHHHH HHHHHHHHHH HCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHCCH HHHHHHHHHH HHHHHHHHHH HCCCCCCHHH HHHHHHHHHC CCCHHHHHHH HHHHHHCCHH HHHHHHHHHH HHHHHHHHHH HHHCHHHHCC CCCHHHHHHH HHHHHHHHHH HHHHHCCCCH HHHHHCCCCH HHHHHHHHHH CCCCCHHHHH HHHHHHHHHH CCCCCCCHHH HHCCCHHHHH HHHHHHHHHH HHHHCCCHHH HCCCHHHHHC CCCHHHHHHH HHHHHHHHHH HHHHHHHHHH CCCCHHHHHH HHHHHHHHHH HHHHHHHHHC CCCHHHHHHH HHHHHHHHHH CCCHHHHHHH HHHHCCCCCH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHC CCCCHHHHHH HHHHHHHHHH HHCHHCCCCC HHHHHHHHHH CCCCHHCCCC CCCCCCCCCC CCC
[Overview]
SLC2A1 -------------------------------------------------------------------------------MEPSSKKLTGRLMLAVGG-AVLGS-LQFGYNTGVINAPQKVI--------------EEFYNQTWVHRYG----ESILPTT----------------------LTTLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPES-------PRFLLINRNEENRAKSV-LKKLRGTA-DVTHDLQEMK-----EESRQMMREKKVTILELFRSP-AYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV-----QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMT-IALALLEQLP--------------------------------------------------------------------------------------------------------------------------WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPY----VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF---RQGGAS-------------------QSDKTPEELF-----HPLGADSQV--------- SLC2A10 ----------------------------------MGHSPPVLPL-----CASVS-------------------------------------LL--------GG-LTFGYELAVISGALLPLQLDF-------------------------------------------------------GLSCLEQEFLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLG---LAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYAL-AGTPWGWRHMFGWATAPAVLQSLSLLFLPAGTDETATHKDLI-PLQG--GEAPKLGPGRPR------------------------------YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGF--HGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALSVSGIGLVSFAVPMD---------------------SGPSCLAVPNATGQTGL---------PGDSGLLQDSSLPPIPRTNEDQR-----EPILSTAKKTKPHPRSGDPSAP-------PRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSW---TFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ-KRRFTLS----FGHRQNS-------------------------TGIPYSRIEISAAS-- SLC2A11 --MEDELEPS---------------------------------------------------------------------LRPRTQIQGRILLLTICA-AGIGGTFQFGYNLSIINAPTLHI--------------QEFTNETWQARTG--------------------------EPLPDHLVLLMW-SLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPES-------PRYLLIDCGDTEACLAA-LRRLRGSG-DLAGELEELE-----EERAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV--P-EAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFT-VALCLQSSFP--------------------------------------------------------------------------------------------------------------------------WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHF----LYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELH-RLN-----------------------------------FPRRAQGPTWRSLEVIQSTEL SLC2A12 --MVPVENTEGP-------SLLNQKGTAVETEGSGSRHPPWARG-----CGMFT-------------------------------------FLSSVT-AAVSG-LLVGYELGIISGALLQIKTLL-------------------------------------------------------ALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI---LSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKYMFGLVIPLGVLQAIAMYFLPPS-------PRFL-VMKGQEGAASKV-LGRLRALS-DTTEELTVIK--------SSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF--QSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFT-HICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHF---------KGISS-HSRSSLMPL-RNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDV-------P------------------AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPW---VCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELA-KVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLEC----NKLCGRGQSR-QLSPET-- SLC2A13 --MSRKASENVEYTLRSLSSLMG------ER---RRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGG-FLFGYDTGVVSGAMLLL-------------KRQL------------------------------------------SLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLA---AANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPES-------PRWL-IQKGQTQKARRI-LSQMRGNQ-TIDEEYDSIKNN--IEEEEKEVGSAGPVICRMLSYP-PTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGV--EDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA-LGFVLSAQVSPRI---------TFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPV-----------NKASTNEAAWGRCENETKFKTEDIFWAYNFCP------------------TPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYG---AFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFD-NRLCTCG-------------------TSDSDEGRYIEYI--RVKGSNYHLSDNDASDVE SLC2A14 --MEFHNGGHVSGIGGFLVSLTS------R-------------------------------------------------MKPHTLAVTPALIFAITV-ATIGS-FQFGYNTGVINAPETII--------------KEFINKTLTDK------ANAPPSEV--------------------LLTNLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPES-------PRFLLINRKKEENATRI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKNHYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMGM-----NSIEPAKETTTNV----- SLC2A2 ---------------------------------------------------------------------------------MTEDKVTGTLVFTVIT-AVLGS-FQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINS------TDELPTISYSMNPKPTPWAEEETVAAAQLITMLW-SLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPES-------PRYLYIKLDEEVKAKQS-LKRLRGYD-DVTKDINEMR-----KEREEASSEQKVSIIQLFTNS-SYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGI-----SKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMS-VGLVLLNKFS--------------------------------------------------------------------------------------------------------------------------WMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPY----VFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQ-KKSGSAH-------------------RP--KAAVEM-----KFLGATETV--------- SLC2A3 -------------MG--------------------------------------------------------------------TQKVTPALIFAITV-ATIGS-FQFGYNTGVINAPEKII--------------KEFINKTLTDK------GNAPPSEV--------------------LLTSLW-SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPES-------PRFLLINRKEEENAKQI-LQRLWGTQ-DVSQDIQEMK-----DESARMSQEKQVTVLELFRVS-SYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV-----QEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMT-VSLLLKDNYN--------------------------------------------------------------------------------------------------------------------------GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAY----VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE-GQAHGAD-------------------RSGKDGVMEM-----NSIEPAKETTTNV----- SLC2A4 MPSGFQQ------IG------SE------D-------------------------------------------------GEPPQQRVTGTLVLAVFS-AVLGS-LQFGYNIGVINAPQKVI--------------EQSYNETWLGRQGPEGPSSIPPGT----------------------LTTLW-ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPES-------PRYLYIIQNLEGPARKS-LKRLTGWA-DVSGVLAELK-----DEKRKLERERPLSLLQLLGSR-THRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV-----GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMT-VALLLLERVP--------------------------------------------------------------------------------------------------------------------------AMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPY----VFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFH--RTPSLL-------------------EQEVKPSTEL-----EYLGPDEND--------- SLC2A5 --MEQQDQSM------------------------------------------------------------------------KEGRLTLVLALATLI-AAFGSSFQYGYNVAAVNSPALLM--------------QQFYNETYYGRTG--------------------------EFMEDFPLTLLW-SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPES-------PRYLLIQKKDEAAAKKA-LQTLRGWD-SVDREVAEIR-----QEDEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV--P-EEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLT-AALALQDTVS--------------------------------------------------------------------------------------------------------------------------WMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPY----SFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFT-KMNKVSE-------------------VYPEKEELKE--------LPPVTSEQ------- SLC2A6 ---------MQE-------PLLGAEGPDYDT---FPEKPPPSPG----------------------------------DRARVGTLQNKRVFLATFA-AVLGN-FSFGYALVYTSPVIPAL-------------ERSLDPDLHLTKSQA--------------------------------------SWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLL------PWRWLAVAGEAPVLIMILLLSFMPNS-------PRFL-LSRGRDEEALRA-LAWLRGTDVDVHWEFEQIQDNVRRQSSRVS--------WAEARAP-HVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP-PKDD---AAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG-LYIHF---GP-----------------RPLSPNSTAGLESE--------SWG-----------------------------DLAQPLAAPAG----------------------------------------YLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR---------------------------------------------------- SLC2A7 --MENKEAGTP---------------------------P-PIP--------------------------------------SREGRLQPTLLLATLS-AAFGSAFQYGYNLSVVNTPHKVF--------------KSFYNETYFERHA--------------------------TFMDGKLMLLLW-SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPES-------PRYSLIQKGDEATARQA-LRRLRGHT-DMEAELEDMR-----AEARAERAEGHLSVLHLCALR-SLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGV--E-AAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLT-VVLLFQNRVP--------------------------------------------------------------------------------------------------------------------------ELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAY----SFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFA-KRNRVKL-------------------PEEKEETIDA--------GPPTASPAKETSF-- SLC2A8 --MTPEDPEETQ-------PLLG---------------PPGGSA----------------------------------PRGR-------RVFLAAFA-AALGP-LSFGFALGYSSPAIPSL-------------QRAAPPAPRLDDAAA--------------------------------------SWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVIT---AAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVL------EWRWLAVLGCVPPSLMLLLMCFMPET-------PRFL-LTQHRRQEAMAA-LRFLWGSEQG--WE-----DPPIGAEQSFH--------LALLRQP-GIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKF-----KDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG-AYFKLTQGGP-----------------GNSSHVAISAPVS-------------------------------------------AQPVDASVG-----------------------------------------LAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG---AFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE-GR--------------------------------------------------------- SLC2A9 --MARKQNRNSKELG--LVPLTD------DT---SHAGP-PGPGRALLECDHLRS---------------GV------PGGRRRKDWSCSLLVASLA-GAFGSSFLYGYNLSVVNAPTPYI--------------KAFYNESWERRHG--------------------------RPIDPDTLTLLW-SVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDS-------PRYLLLEKHNEARAVKA-FQTFLGKA-DVSQEVEEVL-----AESRVQRSIRLVSVLELLRAP-YVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P-PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT-ITLTLQDHAP--------------------------------------------------------------------------------------------------------------------------WVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS-KRNKA----------------------YPPEEKIDSAVTDGKINGRP------------
Variant
check | gene name | residue number | Reference Amino Acid / Variant Amino Acid | minor allele frequency | rs number |
---|---|---|---|---|---|
-- | SLC2A11 | 10 | R/W | 0.0414618 | rs16986337 |
-- | SLC2A11 | 60 | R/H | 0.000222691 | rs569477943 |
-- | SLC2A11 | 67 | D/N | 0.00113324 | rs7292659 |
-- | SLC2A11 | 73 | M/V | 0.000254481 | rs144757871 |
-- | SLC2A11 | 97 | I/T | 0.000258686 | rs148218407 |
-- | SLC2A11 | 98 | T/M | 0.00181125 | rs147655616 |
-- | SLC2A11 | 99 | L/R | 0.000254814 | rs140623928 |
-- | SLC2A11 | 104 | N/S | 0.0036323 | rs11912846 |
-- | SLC2A11 | 123 | R/C | 0.000812402 | rs138317708 |
-- | SLC2A11 | 184 | G/R | 0.000202539 | rs571862746 |
-- | SLC2A11 | 207 | A/V | 0.000543277 | rs149046335 |
-- | SLC2A11 | 221 | R/C | 0.000289027 | rs141517261 |
-- | SLC2A11 | 232 | A/T | 0.000101211 | rs148376745 |
-- | SLC2A11 | 235 | A/P | 0.00247864 | rs34605560 |
-- | SLC2A11 | 238 | R/W | 0.000278281 | rs565121351 |
-- | SLC2A11 | 239 | R/Q | 0.383817 | rs9608213 |
-- | SLC2A11 | 257 | R/H | 0.000279166 | rs200373859 |
-- | SLC2A11 | 266 | R/Q | 0.00111275 | rs192473607 |
-- | SLC2A11 | 308 | R/Q | 0.0029826 | rs36015336 |
-- | SLC2A11 | 340 | E/K | 0.00420521 | rs79905160 |
-- | SLC2A11 | 427 | I/F | 0.00482943 | rs34096096 |
-- | SLC2A11 | 456 | A/T | 0.0247432 | rs60699980 |
-- | SLC2A11 | 476 | K/E | 0.0116075 | rs60882514 |
Phylogenetic tree
Pathway
Priority | Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|---|
main | SLC2A11 | SLC2A11 [plasma membrane] | Cellular hexose transport |
Disease
Gene Name | Reactome (Gene) | Reactome (Pathway) |
---|---|---|
No data |