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Structure
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Variant
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Pathway
Disease

Detail Data SLC19A2


Basic description
Gene Name SLC19A2
Protein Name Thiamine transporter 1 (ThTr-1) (ThTr1) (Solute carrier family 19 member 2) (Thiamine carrier 1) (TC1)
Family SLC19
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490 
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE PFLTPYLLGP DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV VLLQGLSLIV TWFMLLYAQG LLAIQFLEFF YGIATATEIA YYSYIYSVVD LGMYQKVTSY CRSATLVGFT VGSVLGQILV SVAGWSLFSL NVISLTCVSV AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD TPASNHLPGW EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA VGYIKISWST WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY MLLITIATFQ IAANLSMERY ALVFGVNTFI ALALQTLLTL IVVDASGLGL EITTQFLIYA SYFALIAVVF LASGAVSVMK KCRKLEDPQS SSQVTTS 
CCCCCCCCHH HHHHHHHHHH HHHHCCCCCC HHHHHHHHHH HHHHHCCCCC CCCHHHHCCC CCCCCCHHHC CCCCCHHHHH HHHHHHHHHH HHHHHCCHHH HHHHHHHHHH HHHHHHCHHH HHHHHHHHHH HHHHHHHHHH HHHHHHEEEC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCCCCHHHH HHHHHHHHHH HHHHHHHCCC CCHHHHHCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCHHHHHHHH HHHHHHHHHC CCHHHHHHHH HHHHHHCCCH HHHCCHHHHH CCCCCCCCCH HHHCHHHHHH HHHHHHHHHH HHHHHCCCCC CHHHHHHHHH HHHHHHHHHH HHHCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCHHH HHHHHHHHHH HHHHHHHHHH HHCCCCCCCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC CCCCCCC
[Overview] SLC19A1 SLC19A2 SLC19A3 
SLC19A1   MVPSSPAVEKQVPVEPGPDPELRS-------WRHLVCYLCFYGFMAQIRPGESFITPYLLGPDKNFTREQVTNEITPVLSYSYLAVLVPVFLLTDYLRYTPVLLLQGLSFVSVWLLLLLGHSVAHMQLMELFYSVTMAARIAYSSYIFSLVRPARYQRVAGYSRAAVLLGVFTSSVLGQLLVTVGRVSFSTLNYISLAFLTFSVVLALFLKRPKRSLFFNRDDRG--RC--------------------------------ETSASELERMNP-----GPGGKLGHA-LRVACGDSVLARML----RELGDSLRRPQLRLWSLWWVFNSAGYYLVVYYVHILWNEVDPTTNSARVYNGAADAASTLLGAITSFAAGFVKIRWARWSKLLIAGVTATQAGLVFLLAHTRHPSSIWLCYAAFVLFRGSYQFLVPIATFQIASSLSKELCALVFGVNTFFATIVKTIITFIVSDVRGLGLPVRKQFQLYSVYFLILSIIYFL-GAMLDGLRHCQRGHHPRQPPAQGLRSAAEEKAAQALSVQDKGLGGLQPAQSPPLS-PEDSLGAVGPASLEQRQSDPYLAQAPAPQAAEFLSPVTTPSPCTLCSAQASGPEAADETCPQLAVHPPGVSKLGLQCLPSDGVQNVNQ
SLC19A2   MDVPGPVSRRAAAAAAT--VLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPEP-------------------KPDRLLV-LKVLW-NDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAA-IYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTV---GNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLA-SGAVSVMKKCRK-----------------------------------------LEDPQSS------------------------------SQVTTS------------------------------------------------
SLC19A3   MD-----CYRTSLSSS---------------WIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSR-------EIKKSSSVNPVLEETH-------------EGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSS-IYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYT---ANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKD---VQSPA--------------------------PSENPDVSHPEEE------------------------------SNIIMST------------------------------KL---------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC19A2 35 A/V 0.000113744 rs756487822
-- SLC19A2 107 S/G 0.000107862 rs113927216
-- SLC19A2 186 S/L 0.000115416 rs767845548
-- SLC19A2 230 I/F 0.000107375 rs770374931
-- SLC19A2 266 V/M 0.00190069 rs75099879
-- SLC19A2 275 R/L 0.000266665 rs61734338
-- SLC19A2 365 T/S 0.00209272 rs150049339
-- SLC19A2 405 T/A 0.000111498 rs576208768
-- SLC19A2 441 I/T 0.00511572 rs17847484
-- SLC19A2 443 V/I 0.00011935 rs754002628
-- SLC19A2 467 A/T 0.000119503 rs147884156
-- SLC19A2 496 T/A 0.000198948 rs769397647

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
SLC19A2 SLC19A2 [plasma membrane] Vitamin B1 (thiamin) metabolism

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data