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Detail Data SLC18B1


Basic description
Gene Name SLC18B1
Protein Name MFS-type transporter SLC18B1 (Solute carrier family 18 member B1)
Family SLC18
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450 
MEALGDLEGP RAPGGDDPAG SAGETPGWLS REQVFVLISA ASVNLGSMMC YSILGPFFPK EAEKKGASNT IIGMIFGCFA LFELLASLVF GNYLVHIGAK FMFVAGMFVS GGVTILFGVL DRVPDGPVFI AMCFLVRVMD AVSFAAAMTA SSSILAKAFP NNVATVLGSL ETFSGLGLIL GPPVGGFLYQ SFGYEVPFIV LGCVVLLMVP LNMYILPNYE SDPGEHSFWK LIALPKVGLI AFVINSLSSC FGFLDPTLSL FVLEKFNLPA GYVGLVFLGM ALSYAISSPL FGLLSDKRPP LRKWLLVFGN LITAGCYMLL GPVPILHIKS QLWLLVLILV VSGLSAGMSI IPTFPEILSC AHENGFEEGL STLGLVSGLF SAMWSIGAFM GPTLGGFLYE KIGFEWAAAI QGLWALISGL AMGLFYLLEY SRRKRSKSQN ILSTEEERTT LLPNET 
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHCCHH HHHHHHHHHH HHHHHHHHHH CCCCCCHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHCC CCCHHHHHHH HHHHHHHHHH HHHHHHHHHH HCCCHHHHHH HHHHHHHHHH HHHHCCCCCC CCCCCCCHHH HHHCHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC CHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC CHHHHHHHHH HHHHHHHHHH CHHHHHHHHH HHCHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHCCCCCCC CCCCHHHHHH CCCCCC
[Overview] SLC18A1 SLC18A2 SLC18A3 SLC18B1 
SLC18A1   -----------------------MLRTIL-DAPQRLLKEGRASRQLVLVVVFVAL--LLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLG---HAGSSPHALASPAFSTIFSFFNNNTVAVEESV------PSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS---TVMFAFSGT-------YTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQP----SKVSPESAKGT-PLFMLLKDPYILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMG---RWLCSLIGMLVVGTSLLC--VPLAH---NIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRH-------TSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIV--YAPLCYYLRS----PPAK--------EEKLAIL-SQDCPMETRMYATQKPTKEFPL-GEDSDE----------EPDHEE-----
SLC18A2   -----------------------MALSEL--ALVRWLQESRRSRKLILFIVFLAL--LLDNMLLTVVVPIIPSYLYSIKHEKNATEIQTARPVHTAS-----ISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVP-----------SDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVS---TIMFAFSSS-------YAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQP----SRVQPESQKGT-PLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMG---RWLCALLGMIIVGVSILC--IPFAK---NIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRH-------VSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIL--FAPLCFFLRS----PPAK--------EEKMAILMDHNCPIKTKMY-TQNNIQSYPI-GEDEES----------ESD--------
SLC18A3   MESA------------EPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVAL--LLDNMLYMVIVPIVPDYIAHMR--------------GGGEGP----------------TRTPEVWEPTLPLPT-PANASAYTANTSASPTAAWPAGSALRPRYPTES-----EDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFAS---TVLFAFAED-------YATLFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGT-PIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPH-LQWLYGALGLAVIGASSCI--VPACR---SFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRH-------VSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLL--YAPVLLLLRNVGLLTRSR--------SERDVLL---DEPPQG-LY-DAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
SLC18B1   MEALGDLEGPRAPGGDDPAGSAGETPGWL-------------SREQVFVLISAASVNLGSMMCYSILGPFFP---------------------KEAEKKGA--------------------------------------------------------------------SNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAG---MFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNN--VATVLGSLETFSGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNY--------ESDPGEHSFWKLIALPKVGLIAFVINSLSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLFGLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGM---SIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGLWALISGLAMGLFYLLEYSRRKRSKSQNILSTEEERTTLL-----PNET------------------------------------------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC18B1 10 P/T 0.000445529 rs200091558
-- SLC18B1 11 R/L 0.0282596 rs59989552
-- SLC18B1 24 E/K 0.000135307 rs751585034
-- SLC18B1 30 S/P 0.0464596 rs41286192
-- SLC18B1 56 P/Q 0.000171473 rs138609136
-- SLC18B1 71 I/N 0.000207414 rs150134749
-- SLC18B1 73 G/S 0.000144786 rs141721114
-- SLC18B1 82 S/N 0.000175989 rs532206365
-- SLC18B1 204 V/I 0.0806921 rs6926101
-- SLC18B1 205 V/I 0.000109582 rs139842397
-- SLC18B1 215 I/V 0.000869925 rs201837919
-- SLC18B1 218 N/K 0.000151769 rs542007389
-- SLC18B1 240 I/T 0.000107382 rs147348455
-- SLC18B1 270 A/T 0.000175989 rs532206365
-- SLC18B1 274 G/V 0.0010411 rs144106822
-- SLC18B1 403 G/D 0.000254623 rs200678581
-- SLC18B1 410 I/M 0.00368841 rs147717829
-- SLC18B1 441 I/N 0.000330535 rs191172859

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data