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Detail Data SLC16A14


Basic description
Gene Name SLC16A14
Protein Name Monocarboxylate transporter 14 (MCT 14) (Solute carrier family 16 member 14)
Family SLC16
Category -
Reaction name -
Reaction -

Network
Structure


[Overview]
Position 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 9 0 1 0 0 1 1 0 1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0 1 8 0 1 9 0 2 0 0 2 1 0 2 2 0 2 3 0 2 4 0 2 5 0 2 6 0 2 7 0 2 8 0 2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 AA Pred 
        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470        480        490        500        510 
MYTSHEDIGY DFEDGPKDKK TLKPHPNIDG GWAWMMVLSS FFVHILIMGS QMALGVLNVE WLEEFHQSRG LTAWVSSLSM GITLIVGPFI GLFINTCGCR QTAIIGGLVN SLGWVLSAYA ANVHYLFITF GVAAGLGSGM AYLPAVVMVG RYFQKRRALA QGLSTTGTGF GTFLMTVLLK YLCAEYGWRN AMLIQGAVSL NLCVCGALMR PLSPGKNPND PGEKDVRGLP AHSTESVKST GQQGRTEEKD GGLGNEETLC DLQAQECPDQ AGHRKNMCAL RILKTVSWLT MRVRKGFEDW YSGYFGTASL FTNRMFVAFI FWALFAYSSF VIPFIHLPEI VNLYNLSEQN DVFPLTSIIA IVHIFGKVIL GVIADLPCIS VWNVFLLANF TLVLSIFILP LMHTYAGLAV ICALIGFSSG YFSLMPVVTE DLVGIEHLAN AYGIIICANG ISALLGPPFA GWIYDITQKY DFSFYICGLL YMIGILFLLI QPCIRIIEQS RRKYMDGAHV  
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCHH HHHHHHHHHH HHHHHHHHHC CCHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCHHHCHH HHHCCCCCHH HHHHHHHHHH HHHHHHCCCC HHHHHHHHHH HHHHHHHHCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCHHHH HHHHHCCHHC CCCCCCCHHH HHHCHHCHHH HHCHHHHHHH HHHHHHHHHH HHHHHCHHHH HHHCCCCCHH CHHHHHHHHH HHHHHHHHHH HHHCCCCCCC HHHHHHHHHH HHHHHHHHHH HCCCHHHHHH HHHHHCHHCC HHHCHHHHHH HCCCHHHHHH HHHHHHHHHH HHHHHCHHHH HHHHHHCCCC HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHHHHCCCCC
[Overview] SLC16A1 SLC16A10 SLC16A11 SLC16A12 SLC16A13 SLC16A14 SLC16A2 SLC16A3 SLC16A4 SLC16A5 SLC16A6 SLC16A7 SLC16A8 SLC16A9 
SLC16A1   ----------------------------------------------------------MPPAVGGPVGY-------------------------------TPP--DGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATT------SEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPI--------------------GPKPTKAGK---------DKSKAS--LEKAGKSGVKKDL-----------HDANTD------------------------LIGR-HPK--QEKR-------SVFQTINQFL------------------------DLTLFTHR-GFLL-YLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF-LLSILAFVDMVARPSMGLVAN-----TKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLM--DLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFI-------GMGINYRLLAKEQKANEQKKES--------KEEETSIDVAGKPNEVTKAAES--------------------PDQKDTDGGP---------KEE-------ESPV------
SLC16A10  MVLSQEEPDSARG------TSEAQPLG-------------PAPTGAAPP--------PGPGPSDSPEAAVEKVEVELAGPATAEPHEPP-----------EPP--EGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMV-FKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATS-----------------------------------TKDKES------GGSGSSLFSR--------------------------------------------------------------------KKF-------SPPKKIF----------NFAIFKVT-AYAV-WAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEV-VLMCIGVTSGVGRLLFGRIADYVPG-VKKV-----YLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAF--ELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIH-----------SKKQREISKTTGK--------EKME------------------------------------KML----ENQNSLLSSSSGMFKKE-------SDSII-----
SLC16A11  MPA---------------------------------------PQRKHRRGGFSHRCFPTPQTAMTPQPA-------------------------------GPP--DGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSA------QDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPP------------APPRSPLAA------------------------------------------------------------------------------------------------------L------------------------GLSLFTRR-AFSI-FALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLP--GLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYI----------------------------------------------GLPRALPSCGPASPP--------------------ATPPPETGELLPAPQAVLLSPGGPGSTLDTTC------
SLC16A12  MPSGSH--------WT---ANSSKIIT---------WLLE-QPGKEEKRK--------TMAKVNRARST-------------------------------SPP--DGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDY------AQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHT-------------TPEQNHVCRT--------QKED-----------------------------------------------------------IKRVSPYSSLTKEWAQTCLCCCLQQEYSFL------------------------LMS------DFVV-LAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAF-LMSILGVIDIIGNITFGWLTDRR---CLKNYQYVCYLFAVGM--DGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTT--EIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLG-------------FARLIKRMRKTQLQFIA--------KESD--------------------------------------PKLQLWTNGSVAYSVARELDQK--HGEPVATAVPGYSLT
SLC16A13  ---------------------------------------------MARR-------------------T-------------------------------EPP--DGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQA------ARVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAV-----------GGPRAQLT----------------------------------------------------------------------------------------------------------------------------------SLLHHG-PFLR-YTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAF-LLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSL---ALFPVAQAPTA----LVALAVAYGFTSGALAPLAFSVLP--ELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL----------------------------------------------TLPHFFCFSTTTSGPQD-----------------LVTEALDTK--VPLPKEGLEED-----------------
SLC16A14  MYT------------------SHEDIG---------YDFEDGPK-------------------DKKTLK-------------------------------PHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSR------GLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLS------PGK----------NPNDPGEK----DVRGLPAHSTES--VKSTGQQGRTEEK------------DGGLGNEET--------------------LCDLQAQEC-PDQAGHRKNMCAL-----RILKTVSWLTMRVRKGFEDWYSGYFG-TASLFTNR-MFVA-FIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCI-------SVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFS--LMPVVTE-DLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIG--ILFL-------LIQPCIRIIEQSRRK----------------YMD-------------------------------------------------------------------GAHV------
SLC16A2   MALQSQASEEAKGPWQEADQEQQEPVGSPEPESEPEPEPEPEPVPVPPPE-------PQPEPQPLPDPA-PLPELEFESERVHEPEPTPTVETRGTARGFQPP--EGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEE--EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPS-----------------------------------SQDTPS-------KRGVRTLHQ--------------------------------------------------------------------RFL-------AQLRKYF----------NMRVFRQR-TYRI-WAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWV-LLVCIGATSGLGRLVSGHISDSIPG-LKKI-----YLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAF--ELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQ-------RMFKKEQRDSSK---------------D------------------------------------KMLAPDPDPNGELLPGSP----NP-------EEPI------
SLC16A3   --------------------------------------------------------MGGAVVDEGPTGV-------------------------------KAP--DGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGY------SDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPG------------SGPP----------------------------------------------------------------------------------RPSR-------------------RLL------------------------DLSVFRDR-GFVL-YAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFARPAAGFVAG-----LGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLM--AIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL-------GNFFCIR---KKPKEPQPEVAA--------AEEE----KLHKP-P----ADSGVDLREVEHF----------LKAEPEKNGE-------VVHTP-------ETSV------
SLC16A4   ---------------------------------------------MLKREG------------KVQPYT-------------------------------KTL--DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTS------EQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETH--------CHETEESTIKDSTTQKAGLPS-----------KNLTVSQNQSE---------EFYNGPNRNRLLLKSDEESDKVISWSCK----------QLF------------------------DISLFRNP-FFYI-FTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASY-LVSVAGILETVSQIISGWVADQNW--IKKYHYHKSYLI-----LCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLV--DLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFV-----------------------------------------------------------------------------------------------PLAERW------KNSLT-----
SLC16A5   ----------------------------------------------------------------MPQAL-------------------------------ERA--DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASN------SETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETK--------ECPPPPPETP----------------A--LGCLAACGRTIQ----------------------------------------------------------------------RHL------------------------AFDILRHNTGYCV-YILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LISIIGFSNIFLRPLAGLMAG-----RPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLM--DIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM----------GGSFYALQKKEQGKQAVAADALER--DLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWG--------CPASSRTSHEWLLWPKAVLQAK-------QTALGWNSPT
SLC16A6   ---------------------------------------------MTQNK--------LKLCSKANVYT-------------------------------EVP--DGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESN------SRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFI-----------------RGPASPKIVIQ--------ENRKEAQYMLENEKTRTSIDS-----------IDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKA--------------PLL------------------------DFSILKEK-SFIC-YALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAF-LLSTMAIAEVFGRIGAGFVLN-----REPIRKIYIELICVILLTVSL--FAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVR---PCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMD---------------------LAKNEHRVH--------VQMEPV---------------------------------
SLC16A7   ----------------------------------------------------------MPPMPSAPPVH-------------------------------PPP--DGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTY------SEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPL--------------------GPNQTTS------------KSK--------NKTGKTED-------------DSS--------------------------------PKKIKTKK-------STWEKVNKYL------------------------DFSLFKHR-GFLI-YLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVGLIAN-----SKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLM--DLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI-------GNAINYRLLAKERKEENARQKT--------RESE--------PLSKSKHSED--------------------VNVKVSNAQS-------VTSER-------ETNI------
SLC16A8   ------------------------------------------------------MGAGGPRRGEGP------------------------------------P--DGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGY------SDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRP-----PPG------------PGPRPRRDSAG--------DRAGDA--PGEAEADGAGLQL-----------REAS----------------------------PRVRPRR-------------------RLL------------------------DLAVCTDR-AFAV-YAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF-LLSIVGFVDIVARPACGALAG-----LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLM--AAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAV-------ATNCCLRCAKAAPSGPGTEGGASDT--E-DAEAE----GDSEPLPV--VAEEPGNLEALEVLSARGEPTEPEIEARPRLAAE-------SV--------------------
SLC16A9   -----------------------------------------------------------------MELK-------------------------------KSP--DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGK------GKTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQSSDCPLPKK---------IAPEDLPDKYSIYNEKG--KNLEEN--INILDKSYSSEEKCRITLANGDWKQDSLLHKNPT--------------------VTHTKEPETYKKKVAEQTYFC-------KQLAKRKW----------QLYKNYCGETVALFKNK-VFSALFIAILLFDIGGF-PPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWI-------NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWS--IFPYVTT-KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL-------AALPSWDTCNKQLPKPA---------PTTFLYKV-------------------------------------------------------------------ASNV------

Variant
check gene name residue number Reference Amino Acid / Variant Amino Acid minor allele frequency rs number
-- SLC16A14 184 A/T 0.00134531 rs62191755
-- SLC16A14 184 A/S 0.0155307 rs62191755
-- SLC16A14 217 N/D 0.000111615 rs147395915
-- SLC16A14 293 V/I 0.0106215 rs75457118
-- SLC16A14 369 I/L 0.000131229 rs754230670
-- SLC16A14 410 V/L 0.000235035 rs141760905
-- SLC16A14 454 L/F 0.000159071 rs368293302
-- SLC16A14 460 A/G 0.000238686 rs138572804
-- SLC16A14 477 A/V 0.000135006 rs542763388
-- SLC16A14 480 L/F 0.000256842 rs376716027
-- SLC16A14 482 M/I 0.000136186 rs769361932
-- SLC16A14 497 I/V 0.000400122 rs150489031
-- SLC16A14 506 D/G 0.00028503 rs201538649

Phylogenetic tree

Pathway
Priority Gene Name Reactome (Gene) Reactome (Pathway)
No data

Disease
Gene Name Reactome (Gene) Reactome (Pathway)
No data