Detail Data [SLC14A1] | CASLcDB

Gene Name	SLC14A1
Protein Name	Urea transporter 1 (Solute carrier family 14 member 1) (Urea transporter, erythrocyte)
Family	SLC14
Category	Transport of bile salts and organic acids, metal ions and amine compounds
Reaction name	-
Reaction	-

[Overview]

        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440 
MNGRSLIGGA GDARHGPVWK DPFGTKAGDA ARRGIARLSL ALADGSQEQE PEEEIAMEDS PTMVRVDSPT MVRGENQVSP CQGRRCFPKA LGYVTGDMKE LANQLKDKPV VLQFIDWILR GISQVVFVNN PVSGILILVG LLVQNPWWAL TGWLGTVVST LMALLLSQDR SLIASGLYGY NATLVGVLMA VFSDKGDYFW WLLLPVCAMS MTCPIFSSAL NSMLSKWDLP VFTLPFNMAL SMYLSATGHY NPFFPAKLVI PITTAPNISW SDLSALELLK SIPVGVGQIY GCDNPWTGGI FLGAILLSSP LMCLHAAIGS LLGIAAGLSL SAPFEDIYFG LWGFNSSLAC IAMGGMFMAL TWQTHLLALG CALFTAYLGV GMANFMAEVG LPACTWPFCL ATLLFLIMTT KNSNIYKMPL SKVTYPEENR IFYLQAKKRM VESPL 
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCH HHCCCCCHHH HCCCCCCCCC HHHCCCCCCC CCCEECCCCC CCCCCCCCCC CCCCCCCCHH HHHHHCCHHH HHHHHCCCHH HHHHHHHHHH HHHHHHCCCC HHHHHHHHHH HHHCCHHHHH HHHHHHHHHH HHHHHHCCCH HHHHCCHHHH HHHHHHHHHH HHCCCCCHHH HHHHHHHHHH HHHHHHHHHH HHHHCCCCCC HHHHHHHHHH HHHHHHHCCC CCCCCHHHCC CCCCCCCCCC CCCCHHHHHH HCCCCCHHHH CCCCHHHHHH HHHHHHHHCH HHHHHHHHHH HHHHHHHHHC CCCHHHHHHH HHHHHHHHHH HHHHHHHHHC CCHHHHHHHH HHHHHHHHHH HHHHHHHHCC CHHHHHHHHH HHHHHHHHHC CCCCCCCCCC HHCCCCHHHH HHHHHHHHHH HCCCC

Family alignment

[Overview]

SLC14A1   ------------------------------------------------------------------MNGRS----------------------------------------------------------------------------------LIGGAG-------------------DARHG--------------------------------------------------PVWKDPF----------------------------------------------------------------------------------GTKAGDAARRGIA-------------------------------------------------------------------------------------RLSLA--------------LADGSQEQEP------------------------------------------------EEEIAMED-------SPTMVRVDSPTM-----VRGENQVS---------PCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL---------
SLC14A2   MSDPHSSPLLPEPLSSRYKLYEAEFTSPSWPSTSPDTHPALPLLEMPEEKDLRSSNEDSHIVKIEKLNERSKRKDDGVAHRDSAGQRCICLSKAVGYLTGDMKEYRIWLKDKHLALQFIDWVLRGTAQVMFINNPLSGLIIFIGLLIQNPWWTITGGLGTVVSTLTALALGQDRSAIASGLHGYNGMLVGLLMAVFSEKLDYYWWLLFPVTFTAMSCPVLSSALNSIFSKWDLPVFTLPFNIAVTLYLAATGHYNLFFPTTLVEPVSSVPNITWTEMEMPLLLQAIPVGVGQVYGCDNPWTGGVFLVALFISSPLICLHAAIGSIVGLLAALSVATPFETIYTGLWSYNCVLSCIAIGGMFYALTWQTHLLALICALFCAYMEAAISNIMSVVGVPPGTWAFCLATIIFLLLTTNNPAIFRLPLSKVTYPEANRIYYLTVKSGEEEKAPSGGGGEHPPTAGPKVEEGSEAVLSKHRSVFHIEWSSIRRRSKVFGKGEHQERQNKDPFPYRYRKPTVELLDLDTMEESSEIKVETNISKTSWIRSSMAASGKR-VSKALSYITGEMKECGEGLKDKSPVFQFFDWVLRGTSQVMFVNNPLSGILIILGLFIQNPWWAISGCLGTIMSTLTALILSQDKSAIAAGFHGYNGVLVGLLMAVFSDKGDYYWWLLLPVIIMSMSCPILSSALGTIFSKWDLPVFTLPFNITVTLYLAATGHYNLFFPTTLLQPASAMPNITWSEVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLIALFISSPLICLHAAIGSTMGMLAALTIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSVFGLPPCTWPFCLSALTFLLLTTNNPAIYKLPLSKVTYPEANRIYYLSQERNRRASIITKYQAYDVS

check	gene name	residue number	Reference Amino Acid / Variant Amino Acid	minor allele frequency	rs number
--	SLC14A1	4	R/W	0.474158	rs11877062
--	SLC14A1	48	E/K	0.000772828	rs201620887
--	SLC14A1	66	V/M	0.00569068	rs113578396
--	SLC14A1	77	Q/R	0.000362103	rs146079238
	SLC14A1	100	E/K	0.151956	rs2298720
	SLC14A1	120	R/Q	0.000103413	rs114362217
	SLC14A1	121	G/S	0.000135232	rs139053682
	SLC14A1	132	V/I	0.00692047	rs113029149
	SLC14A1	204	L/F	0.000632287	rs563016158
	SLC14A1	223	M/V	0.0174489	rs2298719
	SLC14A1	227	W/R	0.00115341	rs9948825
	SLC14A1	231	V/I	0.00024665	rs138222201
	SLC14A1	250	E/K	0.000175034	rs538368217
	SLC14A1	270	R/W	0.000660271	rs565898944
	SLC14A1	313	C/F	0.000151175	rs201451018
	SLC14A1	336	D/N	0.471467	rs1058396
	SLC14A1	347	S/P	0.00183762	rs78242949
	SLC14A1	355	G/E	0.000175034	rs538368217
	SLC14A1	375	T/M	0.000660271	rs565898944

Detail Data SLC14A1