Detail Data SLC10A3

Basic description

Gene Name	SLC10A3
Protein Name	P3 protein (Solute carrier family 10 member 3)
Family	SLC10
Category	-
Reaction name	-
Reaction	-

Network

Structure

Sequence

[Overview]

        10         20         30         40         50         60         70         80         90        100        110        120        130        140        150        160        170        180        190        200        210        220        230        240        250        260        270        280        290        300        310        320        330        340        350        360        370        380        390        400        410        420        430        440        450        460        470 
MVLMQDKGSS QQWPGLGGEG GGTGPLSMLR AALLLISLPW GAQGTASTSL STAGGHTVPP TGGRYLSIGD GSVMEFEFPE DSEGIIVISS QYPGQANRTA PGPMLRVTSL DTEVLTIKNV SAITWGGGGG FVVSIHSGLA GLAPLHIQLV DAHEAPPTLI EERRDFCIKV SPAEDTPATL SADLAHFSEN PILYLLLPLI FVNKCSFGCK VELEVLKGLM QSPQPMLLGL LGQFLVMPLY AFLMAKVFML PKALALGLII TCSSPGGGGS YLFSLLLGGD VTLAISMTFL STVAATGFLP LSSAIYSRLL SIHETLHVPI SKILGTLLFI AIPIAVGVLI KSKLPKFSQL LLQVVKPFSF VLLLGGLFLA YRMGVFILAG IRLPIVLVGI TVPLVGLLVG YCLATCLKLP VAQRRTVSIE VGVQNSLLAL AMLQLSLRRL QADYASQAPF IVALSGTSEM LALVIGHFIY SSLFPVP 
CCCCCCCCCC CCCCCCCCCC CCCCHHHHHH HHHHHHHHHH HHHHCCCCCC CCCCCCCCCC CCCCEEEECC CCEEEEECCC CCCCEEEEEE ECCCCCCCCC CCCEEEEEEC CCCEEEEEEE EEEECCCCCE EEEEEEECCC EEEEEEEEEE CCCCCCCCCE EEECCCCCCC CCCCCCHHHH HHHHHHCCCH HHHHHHHHHH HHHHHHHHHC CCHHHHHHHH CCCHHHHHHH HHHHHHHHHH HHHHHHHCCC CHHHHHHHHH HHCCCCCCHH HHHHHHHCCC HHHHHHHHHH HHHHHHCCCC HHHHHHHHHH HHHHHCCCCH HHHHCHHHEE ECCHHCCCCC CCCCCCCHHH HHHHCHHHHH HHHHHHHHHH HHHHHHHHCC CCCCHHCCCC HHHHHHHHHH HHHHHHCCCC HHHHEEEEEC CCCCCHHHHH HHHHHHCCHH HHHHHHHHHH HHHHHHHHHH HHHHHHHHHH HHCCCCC

Family alignment

[Overview]

SLC10A1   ----------------------------------------------------MEAHNASA--------------------------------------------------------------------------------PFNFTLPPN-------------------------------------------FGKRPTDLALSV-------ILVFMLFFIML---SLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEAL---AILVCGCSPGGNLSN-VFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIY----SRGIYDGDLKDK-VPYKGIVISL-VLVLIPCTIGIVLK--------SKRPQY----MRYVIK-------------------GGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLN-GRCRRTVSM--ETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEK---------FKTPKDKTKMIYTAATTEETIP------------GALGNGTYKGEDC----------SPCTA-
SLC10A2   --------------MNDPNSC------------------------------VDNATVCSGAS---------------------------------CVVPES---------------------------------------NFNNIL----------------------------------------------------SVVLST-------VLTILLALVMF---SMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAV---VVLIIGCCPGGTASN-ILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIY----TK-MWVDSGSIV-IPYDNIGTSL-VALVVPVSIGMFVN--------HKWPQK----AKIILKIG---------------SIAGAILIVLIAVVGGILY------QSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRC-RTVAF--ETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKK----------CHGKNKAEIPE----SKENGTEPESSFYKAN--GGFQPDEK---------------------
SLC10A3   -----------MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGFVVSI---------HSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATLSADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKVFMLPKALAL---GLIITCSSPGGGGSY-LFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIY----SR-LLSIHETLH-VPISKILGTL-LFIAIPIAVGVLIK--------SKLPKF----SQLLLQVV---------------KPFSFVLLL----GGLFLA-YRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQR-RTVSI--EVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSS----LFPVP---------------------------------------------------------------
SLC10A4   MDGNDNVTLLFAPLLRDNY---------------------------------TLAPNASSLGPG----------------------------TDLALAPASSA-------GPGP------------------GLSLGPGPSFGFSPGPTPTPEPTTSGLAGGAA-------SHGPSPF----PRPWAPHALPFWDTPLNHGLNV-------FVGAALCITML---GLGCTVDVNHFGAHVRRPVGALLAALCQFGLLPLLAFLLALAFKLDEVAAV---AVLLCGCCPGGNLSN-LMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIY----SW-AWINTPIVQLLPLGTVTLTL-CSTLIPIGLGVFIR--------YKYSRV----ADYIVK-------------------VSLWSLLVTLVVLFIMTGTMLGPELLASIPAAVYVIAIFMPLAGYASGYGLATLFHLP-PNCKRTVCL--ETGSQNVQLCTAILKLAFPPQFIGSMYMFPLLYALFQSAEAGIFVLIYKMYGS--------EMLHKRDPLDEDEDTDISYKKLKEEEM--------ADTSYGTVKAENI-IMME-----TAQTSL
SLC10A5   -----MIRKLFIVLL----------------------------LLLVTI----EEARMSSLS-------------FLNIEKTEIL---FFTKTEETILVSSSY---ENKRPNSSHLFVKIEDPKILQMVNVAKKISSDATNFTINL---------VTDEEGETNVTIQLWDSEGRQERLIEEIKNVKVKVLKQKD--SLLQAPM-HIDRN-ILMLILPLILLNKCAFGCKIELQLFQTVWKRPLPVILGAVTQFFLMPFCGFLLSQIVALPEAQAF---GVVMTCTCPGGGGGY-LFALLLDGDFTLAILMTCTSTLLALIMMPVNSYIY----SR-ILGLSGTFH-IPVSKIVSTL-LFILVPVSIGIVIK--------HRIPEK----ASFLERII---------------RPLSFILMF----VGIYLT-FTVGLVFLKTDNLEVILLGLLVPALGLLFGYSFAKVCTLPLPVC-KTVAI--ESGMLNSFLALAVIQLSFPQSKANLASVAPFTVAMCSGCEMLLIIL---VYKAKKRCIFFLQDKRKRN---------------------FLI---------------------------------
SLC10A6   ----------------------------------------------------MRANCSSSSA---------------------------------CPANSSEE-------------------------------ELPVGLEVHGNL----------------------------------------------------ELVFTV-------VSTVMMGLLMF---SLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAI---AVLIMGCCPGGTISN-IFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLY----TW-SWSLQQNLT-IPYQNIGITL-VCLTIPVAFGVYVN--------YRWPKQ----SKIILKIG---------------AVVGGVLLLVVAVAGVVLA------KGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRC-RTISL--ETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRR------LKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGPMDCHRALEPVGHITSCE--
SLC10A7   -----------MRLLE----------------------RMRKDWFMVGI---VLAIAGAKLEP-----------------------------------------------------------------------------SIGVNGGPL---KPEIT------------------------------------------------------VSYIAVATIFF---NSGLSLKTEELTSALVHLKLHLFIQIFTLAFFPATIWLFLQLLSITPINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVITPLLLLLFLGSSSS-----------VPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSSVLLMIIYTTFCDTFSNPNIDLDKFSLVLIL----------------FIIFSIQLSFMLLTFIFSTRNN-SGFTPA-----------DTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLL--IYHPAQILLGSVLVPTIKSWM----------------------VSRQKGVK---------------------------------LTRPTV-

Variant

check	gene name	residue number	Reference Amino Acid / Variant Amino Acid	minor allele frequency	rs number
--	SLC10A3	19	E/K	0.000111384	rs373151341
--	SLC10A3	22	G/S	0.000516408	rs781908353
--	SLC10A3	48	A/T	0.00393675	rs188873885
--	SLC10A3	182	A/T	0.000464118	rs138863812
--	SLC10A3	354	V/I	0.00241764	rs35381503

Phylogenetic tree

Pathway

Priority	Gene Name	Reactome (Gene)	Reactome (Pathway)
No data

Disease

Gene Name	Reactome (Gene)	Reactome (Pathway)
No data